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A matched control group of 4890 persons from the general population was selected by Statistics Sweden. Data from the Swedish Cause of Death Registry was obtained for patients and controls.<\/jats:p>\n              <\/jats:sec>\n              <jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>At a median 5.9 (IQR 4.2\u20138.1) year follow-up, 37% of the iNPH patients and 23% of the controls had died. Mortality was increased in iNPH patients by a hazard ratio of 1.81, 95% CI 1.61\u20132.04, <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001. More pronounced symptoms in the preoperative ordinal gait scale and the Mini-mental State Examination were the most important independent predictors of mortality along with the prevalence of heart disease. Patients who improved in both the gait scale and in the modified Rankin Scale postoperatively (<jats:italic>n<\/jats:italic>\u2009=\u2009144) had a similar survival as the general population (<jats:italic>p<\/jats:italic>\u2009=\u20090.391). Deaths due to cerebrovascular disease or dementia were more common in iNPH patients, while more controls died because of neoplasms or disorders of the circulatory system.<\/jats:p>\n              <\/jats:sec>\n              <jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Mortality in operated iNPH patients is 1.8 times increased compared to the general population, a lower figure than previously reported. The survival of iNPH patients who improve in gait and functional independence is similar to that of the general population, indicating that shunt surgery for iNPH, besides improving symptoms and signs, can normalize survival.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00415-019-09598-1","type":"journal-article","created":{"date-parts":[[2019,11,11]],"date-time":"2019-11-11T13:03:23Z","timestamp":1573477403000},"page":"640-648","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":41,"title":["Survival in treated idiopathic normal pressure hydrocephalus"],"prefix":"10.1007","volume":"267","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6797-6348","authenticated-orcid":false,"given":"Kerstin","family":"Andr\u00e9n","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1720-7633","authenticated-orcid":false,"given":"Carsten","family":"Wikkels\u00f8","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3486-5251","authenticated-orcid":false,"given":"Nina","family":"Sundstr\u00f6m","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0125-9589","authenticated-orcid":false,"given":"Hanna","family":"Israelsson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6695-7049","authenticated-orcid":false,"given":"Simon","family":"Agerskov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7504-8354","authenticated-orcid":false,"given":"Katarina","family":"Laurell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9803-7271","authenticated-orcid":false,"given":"Per","family":"Hellstr\u00f6m","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4997-5266","authenticated-orcid":false,"given":"Mats","family":"Tullberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2019,11,11]]},"reference":[{"key":"9598_CR1","doi-asserted-by":"publisher","first-page":"1449","DOI":"10.1212\/WNL.0000000000000342","volume":"82","author":"D Jaraj","year":"2014","unstructured":"Jaraj D, Rabiei K, Marlow T, Jensen C, Skoog I, Wikkelso C (2014) Prevalence of idiopathic normal-pressure hydrocephalus. 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Dr. Andr\u00e9n, Dr. Sundstr\u00f6m, Dr. Israelsson, Dr. Agerskov, Dr. Laurell, Dr. Hellstr\u00f6m, and Dr. Tullberg report no disclosures.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"The study was approved by the Regional Ethical Review Board in Gothenburg (Dnr 492-14, with addition T006-15).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical standard"}}]}}