{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T17:25:22Z","timestamp":1790616322186,"version":"4.1.0"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2020,1,29]],"date-time":"2020-01-29T00:00:00Z","timestamp":1580256000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,1,29]],"date-time":"2020-01-29T00:00:00Z","timestamp":1580256000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"name":"French Ministry of Health with the participation of the Groupement Interr\u00e9gional de Recherche Clinique et d\u2019Innovation Sud-Ouest Outre-Mer Hospitalier","award":["PHRC 2011-A01091-40"],"award-info":[{"award-number":["PHRC 2011-A01091-40"]}]},{"DOI":"10.13039\/100010663","name":"H2020 European Research Council","doi-asserted-by":"publisher","award":["615102"],"award-info":[{"award-number":["615102"]}],"id":[{"id":"10.13039\/100010663","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Occitanie Region","award":["14054344"],"award-info":[{"award-number":["14054344"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Neurol"],"published-print":{"date-parts":[[2020,5]]},"DOI":"10.1007\/s00415-019-09689-z","type":"journal-article","created":{"date-parts":[[2020,1,29]],"date-time":"2020-01-29T20:03:37Z","timestamp":1580328217000},"page":"1389-1400","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Biomechanical response of the CNS is associated with frailty in NPH-suspected patients"],"prefix":"10.1007","volume":"267","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4772-8512","authenticated-orcid":false,"given":"A.","family":"Vallet","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Del Campo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9660-5108","authenticated-orcid":false,"given":"E. O.","family":"Hoogendijk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Lokossou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.","family":"Bal\u00e9dent","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z.","family":"Czosnyka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Balardy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1374-1620","authenticated-orcid":false,"given":"P.","family":"Payoux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Swider","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0711-3695","authenticated-orcid":false,"given":"S.","family":"Lorthois","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Schmidt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,1,29]]},"reference":[{"key":"9689_CR1","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/S1474-4422(09)70299-6","volume":"9","author":"CR Jack","year":"2010","unstructured":"Jack CR, Knopman DS, Jagust WJ et al (2010) Hypothetical model of dynamic biomarkers of the Alzheimer\u2019s pathological cascade. Lancet Neurol 9:119\u2013128. https:\/\/doi.org\/10.1016\/S1474-4422(09)70299-6","journal-title":"Lancet Neurol"},{"key":"9689_CR2","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1038\/nrneurol.2012.241","volume":"9","author":"RA Sperling","year":"2013","unstructured":"Sperling RA, Karlawish J, Johnson KA (2013) Preclinical Alzheimer disease-the challenges ahead. Nat Rev Neurol 9:54\u201358. https:\/\/doi.org\/10.1038\/nrneurol.2012.241","journal-title":"Nat Rev Neurol"},{"key":"9689_CR3","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1016\/j.exger.2012.10.004","volume":"48","author":"M Cesari","year":"2013","unstructured":"Cesari M, Vellas B, Gambassi G (2013) The stress of aging. Exp Gerontol 48:451\u2013456. https:\/\/doi.org\/10.1016\/j.exger.2012.10.004","journal-title":"Exp Gerontol"},{"key":"9689_CR4","doi-asserted-by":"publisher","first-page":"881","DOI":"10.1016\/j.jamda.2016.05.013","volume":"17","author":"G Kojima","year":"2016","unstructured":"Kojima G, Taniguchi Y, Iliffe S, Walters K (2016) Frailty as a predictor of alzheimer disease, vascular dementia, and all dementia among community-dwelling older people: a systematic review and meta-analysis. J Am Med Dir Assoc 17:881\u2013888. https:\/\/doi.org\/10.1016\/j.jamda.2016.05.013","journal-title":"J Am Med Dir Assoc"},{"key":"9689_CR5","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1186\/s13195-014-0054-5","volume":"6","author":"X Song","year":"2014","unstructured":"Song X, Mitnitski A, Rockwood K (2014) Age-related deficit accumulation and the risk of late-life dementia. Alzheimers Res Ther 6:54. https:\/\/doi.org\/10.1186\/s13195-014-0054-5","journal-title":"Alzheimers Res Ther"},{"key":"9689_CR6","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1212\/WNL.0b013e318225c6bc","volume":"77","author":"X Song","year":"2011","unstructured":"Song X, Mitnitski A, Rockwood K (2011) Nontraditional risk factors combine to predict Alzheimer disease and dementia. Neurology 77:227\u2013234. https:\/\/doi.org\/10.1212\/WNL.0b013e318225c6bc","journal-title":"Neurology"},{"key":"9689_CR7","doi-asserted-by":"publisher","first-page":"e162","DOI":"10.1212\/WNL.0000000000005761","volume":"91","author":"H Oppenheim","year":"2018","unstructured":"Oppenheim H, Paolillo EW, Moore RC et al (2018) Neurocognitive functioning predicts frailty index in HIV. Neurology 91:e162\u2013e170. https:\/\/doi.org\/10.1212\/WNL.0000000000005761","journal-title":"Neurology"},{"key":"9689_CR8","doi-asserted-by":"publisher","first-page":"840","DOI":"10.1016\/j.arr.2013.06.004","volume":"12","author":"DA Robertson","year":"2013","unstructured":"Robertson DA, Savva GM, Kenny RA (2013) Frailty and cognitive impairment\u2013a review of the evidence and causal mechanisms. Ageing Res Rev 12:840\u2013851. https:\/\/doi.org\/10.1016\/j.arr.2013.06.004","journal-title":"Ageing Res Rev"},{"key":"9689_CR9","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1093\/ageing\/afs185","volume":"42","author":"DB Rolfson","year":"2013","unstructured":"Rolfson DB, Wilcock G, Mitnitski A et al (2013) An assessment of neurocognitive speed in relation to frailty. Age Ageing 42:191\u2013196. https:\/\/doi.org\/10.1093\/ageing\/afs185","journal-title":"Age Ageing"},{"key":"9689_CR10","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1016\/j.neurobiolaging.2018.06.032","volume":"70","author":"IMJ Kant","year":"2018","unstructured":"Kant IMJ, de Bresser J, van Montfort SJT et al (2018) The association between brain volume, cortical brain infarcts, and physical frailty. Neurobiol Aging 70:247\u2013253. https:\/\/doi.org\/10.1016\/j.neurobiolaging.2018.06.032","journal-title":"Neurobiol Aging"},{"key":"9689_CR11","doi-asserted-by":"publisher","first-page":"1623","DOI":"10.3233\/JAD-170938","volume":"62","author":"M Gallucci","year":"2018","unstructured":"Gallucci M, Piovesan C, Di Battista ME (2018) Associations between the Frailty Index and Brain Atrophy: the Treviso Dementia (TREDEM) Registry. J Alzheimers Dis 62:1623\u20131634. https:\/\/doi.org\/10.3233\/JAD-170938","journal-title":"J Alzheimers Dis"},{"key":"9689_CR12","doi-asserted-by":"publisher","first-page":"2055","DOI":"10.1212\/WNL.0b013e318294b462","volume":"80","author":"AS Buchman","year":"2013","unstructured":"Buchman AS, Yu L, Wilson RS et al (2013) Association of brain pathology with the progression of frailty in older adults. Neurology 80:2055\u20132061. https:\/\/doi.org\/10.1212\/WNL.0b013e318294b462","journal-title":"Neurology"},{"key":"9689_CR13","doi-asserted-by":"publisher","first-page":"931","DOI":"10.1007\/s10237-015-0662-4","volume":"14","author":"A Goriely","year":"2015","unstructured":"Goriely A, Geers MGD, Holzapfel GA et al (2015) Mechanics of the brain: perspectives, challenges, and opportunities. Biomech Model Mechanobiol 14:931\u2013965. https:\/\/doi.org\/10.1007\/s10237-015-0662-4","journal-title":"Biomech Model Mechanobiol"},{"key":"9689_CR14","doi-asserted-by":"publisher","first-page":"9894","DOI":"10.1073\/pnas.1706942114","volume":"114","author":"KE Holter","year":"2017","unstructured":"Holter KE, Kehlet B, Devor A et al (2017) Interstitial solute transport in 3D reconstructed neuropil occurs by diffusion rather than bulk flow. Proc Natl Acad Sci 114:9894\u20139899. https:\/\/doi.org\/10.1073\/pnas.1706942114","journal-title":"Proc Natl Acad Sci"},{"key":"9689_CR15","doi-asserted-by":"publisher","first-page":"413","DOI":"10.1038\/s41593-018-0329-4","volume":"22","author":"JCC Hern\u00e1ndez","year":"2019","unstructured":"Hern\u00e1ndez JCC, Bracko O, Kersbergen CJ et al (2019) Neutrophil adhesion in brain capillaries reduces cortical blood flow and impairs memory function in Alzheimer\u2019s disease mouse models. Nat Neurosci 22:413. https:\/\/doi.org\/10.1038\/s41593-018-0329-4","journal-title":"Nat Neurosci"},{"key":"9689_CR16","doi-asserted-by":"publisher","first-page":"1119","DOI":"10.1212\/WNL.0b013e31822f02f5","volume":"77","author":"BT Klassen","year":"2011","unstructured":"Klassen BT, Ahlskog JE (2011) Normal pressure hydrocephalus. Neurology 77:1119. https:\/\/doi.org\/10.1212\/WNL.0b013e31822f02f5","journal-title":"Neurology"},{"issue":"1","key":"9689_CR17","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1186\/2045-8118-10-22","volume":"10","author":"Jan Malm","year":"2013","unstructured":"Malm J, Graff-Radford NR, Ishikawa M, et al. (2013) Influence of comorbidities in idiopathic normal pressure hydrocephalus \u2014 research and clinical care. A report of the ISHCSF task force on comorbidities in INPH. Fluids Barriers CNS 10:22. https:\/\/doi.org\/10.1186\/2045-8118-10-22**","journal-title":"Fluids and Barriers of the CNS"},{"key":"9689_CR18","doi-asserted-by":"publisher","first-page":"987","DOI":"10.3171\/jns.2005.102.6.0987","volume":"102","author":"A Marmarou","year":"2005","unstructured":"Marmarou A, Young HF, Aygok GA et al (2005) Diagnosis and management of idiopathic normal-pressure hydrocephalus: a prospective study in 151 patients. J Neurosurg 102:987\u2013997. https:\/\/doi.org\/10.3171\/jns.2005.102.6.0987","journal-title":"J Neurosurg"},{"key":"9689_CR19","doi-asserted-by":"publisher","DOI":"10.1227\/01.neu.0000168185.29659.c5","author":"N Relkin","year":"2005","unstructured":"Relkin N, Marmarou A, Klinge P et al (2005) Diagnosing idiopathic normal-pressure hydrocephalus. Neurosurgery. https:\/\/doi.org\/10.1227\/01.neu.0000168185.29659.c5","journal-title":"Neurosurgery"},{"key":"9689_CR20","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1016\/S0899-9007(98)00171-3","volume":"15","author":"B Vellas","year":"1999","unstructured":"Vellas B, Guigoz Y, Garry PJ et al (1999) The mini nutritional assessment (MNA) and its use in grading the nutritional state of elderly patients. Nutrition 15:116\u2013122. https:\/\/doi.org\/10.1016\/S0899-9007(98)00171-3","journal-title":"Nutrition"},{"key":"9689_CR21","first-page":"513","volume":"73","author":"E Feck","year":"2018","unstructured":"Feck E, Zulfiqar AA (2018) Screening of frailty in family practice by the modified SEGA grid. Rev Med Liege 73:513\u2013518","journal-title":"Rev Med Liege"},{"key":"9689_CR22","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1136\/jnnp.68.4.429","volume":"68","author":"I Araki","year":"2000","unstructured":"Araki I, Kuno S (2000) Assessment of voiding dysfunction in Parkinson\u2019s disease by the international prostate symptom score. J Neurol Neurosurg Psychiatry 68:429\u2013433. https:\/\/doi.org\/10.1136\/jnnp.68.4.429","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"9689_CR23","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1016\/j.dadm.2017.02.004","volume":"6","author":"Y Mo","year":"2017","unstructured":"Mo Y, Stromswold J, Wilson K et al (2017) A multinational study distinguishing Alzheimer\u2019s and healthy patients using cerebrospinal fluid tau\/A\u03b242 cutoff with concordance to amyloid positron emission tomography imaging. Alzheimers Dement Diagn Assess Dis Monit 6:201\u2013209. https:\/\/doi.org\/10.1016\/j.dadm.2017.02.004","journal-title":"Alzheimers Dement Diagn Assess Dis Monit"},{"key":"9689_CR24","doi-asserted-by":"publisher","first-page":"351","DOI":"10.2214\/ajr.149.2.351","volume":"149","author":"F Fazekas","year":"1987","unstructured":"Fazekas F, Chawluk JB, Alavi A et al (1987) MR signal abnormalities at 1.5 T in Alzheimer\u2019s dementia and normal aging. AJR Am J Roentgenol 149:351\u2013356. https:\/\/doi.org\/10.2214\/ajr.149.2.351","journal-title":"AJR Am J Roentgenol"},{"key":"9689_CR25","doi-asserted-by":"publisher","first-page":"368","DOI":"10.1097\/00004424-200107000-00003","volume":"36","author":"O Bal\u00e9dent","year":"2001","unstructured":"Bal\u00e9dent O, Henry-Feugeas M-C, Idy-Peretti I (2001) Cerebrospinal fluid dynamics and relation with blood flow: a magnetic resonance study with semiautomated cerebrospinal fluid segmentation. Invest Radiol 36:368","journal-title":"Invest Radiol"},{"key":"9689_CR26","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1212\/01.wnl.0000250270.54587.71","volume":"68","author":"N Lenfeldt","year":"2007","unstructured":"Lenfeldt N, Koskinen L-OD, Bergenheim AT et al (2007) CSF pressure assessed by lumbar puncture agrees with intracranial pressure. Neurology 68:155\u2013158. https:\/\/doi.org\/10.1212\/01.wnl.0000250270.54587.71","journal-title":"Neurology"},{"key":"9689_CR27","doi-asserted-by":"publisher","first-page":"19","DOI":"10.3171\/jns.1977.47.1.0019","volume":"47","author":"J Szewczykowski","year":"1977","unstructured":"Szewczykowski J, liwka S, Kunicki A et al (1977) A fast method of estimating the elastance of the intracranial system. J Neurosurg 47:19\u201326. https:\/\/doi.org\/10.3171\/jns.1977.47.1.0019","journal-title":"J Neurosurg"},{"key":"9689_CR28","doi-asserted-by":"publisher","first-page":"332","DOI":"10.3171\/jns.1978.48.3.0332","volume":"48","author":"A Marmarou","year":"1978","unstructured":"Marmarou A, Shulman K, Rosende RM (1978) A nonlinear analysis of the cerebrospinal fluid system and intracranial pressure dynamics. J Neurosurg 48:332\u2013344. https:\/\/doi.org\/10.3171\/jns.1978.48.3.0332","journal-title":"J Neurosurg"},{"key":"9689_CR29","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1145\/358669.358692","volume":"24","author":"MA Fischler","year":"1981","unstructured":"Fischler MA, Bolles RC (1981) Random sample consensus: a paradigm for model fitting with applications to image analysis and automated cartography. Commun ACM 24:381\u2013395. https:\/\/doi.org\/10.1145\/358669.358692","journal-title":"Commun ACM"},{"key":"9689_CR30","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1186\/1471-2318-8-24","volume":"8","author":"SD Searle","year":"2008","unstructured":"Searle SD, Mitnitski A, Gahbauer EA et al (2008) A standard procedure for creating a frailty index. BMC Geriatr 8:24. https:\/\/doi.org\/10.1186\/1471-2318-8-24","journal-title":"BMC Geriatr"},{"key":"9689_CR31","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/j.cger.2010.08.008","volume":"27","author":"K Rockwood","year":"2011","unstructured":"Rockwood K, Mitnitski A (2011) Frailty defined by deficit accumulation and geriatric medicine defined by frailty. Clin Geriatr Med 27:17\u201326. https:\/\/doi.org\/10.1016\/j.cger.2010.08.008","journal-title":"Clin Geriatr Med"},{"key":"9689_CR32","first-page":"328","volume":"28","author":"B V\u00e1s\u00e1rhelyi","year":"2017","unstructured":"V\u00e1s\u00e1rhelyi B, Debreczeni LA (2017) Lab test findings in the elderly. EJIFCC 28:328\u2013332","journal-title":"EJIFCC"},{"key":"9689_CR33","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/S1474-4422(16)30291-5","volume":"16","author":"DJ Irwin","year":"2017","unstructured":"Irwin DJ, Grossman M, Weintraub D et al (2017) Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies: a retrospective analysis. Lancet Neurol 16:55\u201365. https:\/\/doi.org\/10.1016\/S1474-4422(16)30291-5","journal-title":"Lancet Neurol"},{"key":"9689_CR34","doi-asserted-by":"publisher","first-page":"11934","DOI":"10.1038\/ncomms11934","volume":"7","author":"Y Iturria-Medina","year":"2016","unstructured":"Iturria-Medina Y, Sotero RC, Toussaint PJ et al (2016) Early role of vascular dysregulation on late-onset Alzheimer\/\u2019s disease based on multifactorial data-driven analysis. Nat Commun 7:11934. https:\/\/doi.org\/10.1038\/ncomms11934","journal-title":"Nat Commun"},{"key":"9689_CR35","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1093\/imammb\/dqn021","volume":"26","author":"B Wirth","year":"2009","unstructured":"Wirth B, Sobey I (2009) Analytic solution during an infusion test of the linear unsteady poroelastic equations in a spherically symmetric model of the brain. Math Med Biol J IMA 26:25\u201361. https:\/\/doi.org\/10.1093\/imammb\/dqn021","journal-title":"Math Med Biol J IMA"},{"key":"9689_CR36","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/j.arr.2016.01.002","volume":"30","author":"L Pini","year":"2016","unstructured":"Pini L, Pievani M, Bocchetta M et al (2016) Brain atrophy in Alzheimer\u2019s Disease and aging. Ageing Res Rev 30:25\u201348. https:\/\/doi.org\/10.1016\/j.arr.2016.01.002","journal-title":"Ageing Res Rev"},{"key":"9689_CR37","doi-asserted-by":"publisher","first-page":"494","DOI":"10.1002\/jmri.22707","volume":"34","author":"MC Murphy","year":"2011","unstructured":"Murphy MC, Huston J, Jack CR et al (2011) Decreased brain stiffness in Alzheimer\u2019s disease determined by magnetic resonance elastography. J Magn Reson Imaging JMRI 34:494\u2013498. https:\/\/doi.org\/10.1002\/jmri.22707","journal-title":"J Magn Reson Imaging JMRI"},{"key":"9689_CR38","doi-asserted-by":"publisher","first-page":"e23451","DOI":"10.1371\/journal.pone.0023451","volume":"6","author":"I Sack","year":"2011","unstructured":"Sack I, Streitberger K-J, Krefting D et al (2011) The influence of physiological aging and atrophy on brain viscoelastic properties in humans. PLOS One 6:e23451. https:\/\/doi.org\/10.1371\/journal.pone.0023451","journal-title":"PLOS One"},{"key":"9689_CR39","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1002\/nbm.1602","volume":"24","author":"K-J Streitberger","year":"2011","unstructured":"Streitberger K-J, Wiener E, Hoffmann J et al (2011) In vivo viscoelastic properties of the brain in normal pressure hydrocephalus. NMR Biomed 24:385\u2013392. https:\/\/doi.org\/10.1002\/nbm.1602","journal-title":"NMR Biomed"},{"key":"9689_CR40","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1159\/000335155","volume":"10","author":"V Leinonen","year":"2012","unstructured":"Leinonen V, Koivisto AM, Alafuzoff I et al (2012) cortical brain biopsy in long-term prognostication of 468 patients with possible normal pressure hydrocephalus. Neurodegener Dis 10:166\u2013169. https:\/\/doi.org\/10.1159\/000335155","journal-title":"Neurodegener Dis"},{"key":"9689_CR41","doi-asserted-by":"publisher","first-page":"592","DOI":"10.1212\/WNL.0000000000002369","volume":"86","author":"D Jaraj","year":"2016","unstructured":"Jaraj D, Agerskov S, Rabiei K et al (2016) Vascular factors in suspected normal pressure hydrocephalus. Neurology 86:592. https:\/\/doi.org\/10.1212\/WNL.0000000000002369","journal-title":"Neurology"},{"key":"9689_CR42","doi-asserted-by":"publisher","first-page":"752","DOI":"10.1016\/S0140-6736(12)62167-9","volume":"381","author":"A Clegg","year":"2013","unstructured":"Clegg A, Young J, Iliffe S et al (2013) Frailty in elderly people. Lancet 381:752\u2013762. https:\/\/doi.org\/10.1016\/S0140-6736(12)62167-9","journal-title":"Lancet"},{"key":"9689_CR43","doi-asserted-by":"publisher","first-page":"355","DOI":"10.3233\/JAD-141884","volume":"44","author":"J Stone","year":"2015","unstructured":"Stone J, Johnstone DM, Mitrofanis J, O\u2019Rourke M (2015) The mechanical cause of age-related dementia (Alzheimer\u2019s disease): the brain is destroyed by the pulse. J Alzheimers Dis 44:355\u2013373. https:\/\/doi.org\/10.3233\/JAD-141884","journal-title":"J Alzheimers Dis"},{"key":"9689_CR44","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1186\/s13195-014-0082-1","volume":"6","author":"J Rahimi","year":"2014","unstructured":"Rahimi J, Kovacs GG (2014) Prevalence of mixed pathologies in the aging brain. Alzheimer\u2019s Res Ther 6:82. https:\/\/doi.org\/10.1186\/s13195-014-0082-1","journal-title":"Alzheimer\u2019s Res Ther"},{"key":"9689_CR45","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2019.00723","author":"MGM Olde Rikkert","year":"2019","unstructured":"Olde Rikkert MGM, Melis RJF (2019) Rerouting geriatric medicine by complementing static frailty measures with dynamic resilience indicators of recovery potential. Front Physiol. https:\/\/doi.org\/10.3389\/fphys.2019.00723","journal-title":"Front Physiol"},{"key":"9689_CR46","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2018.00275","author":"TK Khan","year":"2018","unstructured":"Khan TK (2018) An algorithm for preclinical diagnosis of alzheimer\u2019s disease. Front Neurosci. https:\/\/doi.org\/10.3389\/fnins.2018.00275","journal-title":"Front Neurosci"},{"key":"9689_CR47","doi-asserted-by":"publisher","first-page":"533","DOI":"10.3233\/JAD-180199","volume":"64","author":"NM Payton","year":"2018","unstructured":"Payton NM, Kalpouzos G, Rizzuto D et al (2018) Combining cognitive, genetic, and structural neuroimaging markers to identify individuals with increased dementia risk. J Alzheimers Dis JAD 64:533\u2013542. https:\/\/doi.org\/10.3233\/JAD-180199","journal-title":"J Alzheimers Dis JAD"},{"key":"9689_CR48","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/jmri.10133","volume":"16","author":"A Spilt","year":"2002","unstructured":"Spilt A, Box FMA, van der Geest RJ et al (2002) Reproducibility of total cerebral blood flow measurements using phase contrast magnetic resonance imaging. J Magn Reson Imaging JMRI 16:1\u20135. https:\/\/doi.org\/10.1002\/jmri.10133","journal-title":"J Magn Reson Imaging JMRI"},{"key":"9689_CR49","doi-asserted-by":"publisher","DOI":"10.4103\/sni.sni_403_16","author":"MN Khan","year":"2017","unstructured":"Khan MN, Shallwani H, Khan MU, Shamim MS (2017) Noninvasive monitoring intracranial pressure: a review of available modalities. Surg Neurol Int. https:\/\/doi.org\/10.4103\/sni.sni_403_16","journal-title":"Surg Neurol Int"}],"container-title":["Journal of Neurology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00415-019-09689-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00415-019-09689-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00415-019-09689-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,1,28]],"date-time":"2021-01-28T00:22:27Z","timestamp":1611793347000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00415-019-09689-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1,29]]},"references-count":49,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,5]]}},"alternative-id":["9689"],"URL":"https:\/\/doi.org\/10.1007\/s00415-019-09689-z","relation":{},"ISSN":["0340-5354","1432-1459"],"issn-type":[{"value":"0340-5354","type":"print"},{"value":"1432-1459","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1,29]]},"assertion":[{"value":"2 September 2019","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 December 2019","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 December 2019","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 January 2020","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"On behalf of all authors, the corresponding author states that there is no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}]}}