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F. Agosta is Section Editor of NeuroImage: Clinical; has received speaker honoraria from Philips, Novartis and Biogen Idec; and receives or has received research supports from the Italian Ministry of Health, AriSLA (Fondazione Italiana di Ricerca per la SLA), and the European Research Council. E. Canu has received research supports from the Italian Ministry of Health. V. Bessi, S. Mazzeo, S. Padigioni, D. Simoni, B. Nacmias, S. Sorbi report no actual or potential conflicts of interest. D. Calderaro, V. Castelnovo, M. Leocadi, C. Cividini report no actual or potential conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"This study has been approved by the local ethics committee and has been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The patient gave her informed consent prior to her inclusion in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"All data needed to evaluate the conclusions in the paper are present in the paper and\/or in the Supplementary Materials. Additional data related to this paper may be requested from the corresponding author. Specifically, qualified academic investigators may request participant-level, de-identifed clinical data and supporting documents (statistical analysis plan and protocol) pertaining to this study.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Availability of data and material"}}]}}