{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T08:55:36Z","timestamp":1788857736975,"version":"build-2803163510"},"reference-count":39,"publisher":"Springer Science and Business Media LLC","issue":"S1","license":[{"start":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T00:00:00Z","timestamp":1594598400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T00:00:00Z","timestamp":1594598400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","award":["01EO1401"],"award-info":[{"award-number":["01EO1401"]}],"id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003493","name":"Gemeinn\u00fctzige Hertie-Stiftung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003493","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005722","name":"Ludwig-Maximilians-Universit\u00e4t M\u00fcnchen","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100005722","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Neurol"],"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Background<\/jats:title>\n                <jats:p>Spontaneous episodic vertigo syndromes, namely vestibular migraine (VM) and Meni\u00e8re\u2019s disease (MD), are difficult to differentiate, even for an experienced clinician. In the presence of complex diagnostic information, automated systems can support human decision making. Recent developments in machine learning might facilitate bedside diagnosis of VM and MD.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Data of this study originate from the prospective patient registry of the German Centre for Vertigo and Balance Disorders, a specialized tertiary treatment center at the University Hospital Munich. The classification task was to differentiate cases of VM, MD from other vestibular disease entities. Deep Neural Networks (DNN) and Boosted Decision Trees (BDT) were used for classification.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>A total of 1357 patients were included (mean age 52.9, SD 15.9, 54.7% female), 9.9% with MD and 15.6% with VM. DNN models yielded an accuracy of 98.4\u2009\u00b1\u20090.5%, a precision of 96.3\u2009\u00b1\u20093.9%, and a sensitivity of 85.4\u2009\u00b1\u20093.9% for VM, and an accuracy of 98.0\u2009\u00b1\u20091.0%, a precision of 90.4\u2009\u00b1\u20096.2% and a sensitivity of 89.9\u2009\u00b1\u20094.6% for MD. BDT yielded an accuracy of 84.5\u2009\u00b1\u20090.5%, precision of 51.8\u2009\u00b1\u20096.1%, sensitivity of 16.9\u2009\u00b1\u20091.7% for VM, and an accuracy of 93.3\u2009\u00b1\u20090.7%, precision 76.0\u2009\u00b1\u20096.7%, sensitivity 41.7\u2009\u00b1\u20092.9% for MD.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>The correct diagnosis of spontaneous episodic vestibular syndromes is challenging in clinical practice. Modern machine learning methods might be the basis for developing systems that assist practitioners and clinicians in their daily treatment decisions.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00415-020-10061-9","type":"journal-article","created":{"date-parts":[[2020,7,13]],"date-time":"2020-07-13T11:04:08Z","timestamp":1594638248000},"page":"160-167","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Development and validation of a classification algorithm to diagnose and differentiate spontaneous episodic vertigo syndromes: results from the DizzyReg patient registry"],"prefix":"10.1007","volume":"267","author":[{"given":"Michael","family":"Groezinger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doreen","family":"Huppert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralf","family":"Strobl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0273-7984","authenticated-orcid":false,"given":"Eva","family":"Grill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,7,13]]},"reference":[{"issue":"6","key":"10061_CR1","doi-asserted-by":"publisher","first-page":"1028","DOI":"10.1212\/01.wnl.0000237539.09942.06","volume":"67","author":"HK Neuhauser","year":"2006","unstructured":"Neuhauser HK, Radtke A, von Brevern M, Feldmann M, Lezius F, Ziese T, Lempert T (2006) Migrainous vertigo: prevalence and impact on quality of life. Neurology 67(6):1028\u20131033. https:\/\/doi.org\/10.1212\/01.wnl.0000237539.09942.06","journal-title":"Neurology"},{"issue":"6","key":"10061_CR2","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1038\/nrneurol.2017.58","volume":"13","author":"T Brandt","year":"2017","unstructured":"Brandt T, Dieterich M (2017) The dizzy patient: don\u2019t forget disorders of the central vestibular system. Nat Rev Neurol 13(6):352\u2013362. https:\/\/doi.org\/10.1038\/nrneurol.2017.58","journal-title":"Nat Rev Neurol"},{"issue":"9","key":"10061_CR3","doi-asserted-by":"publisher","first-page":"1393","DOI":"10.1111\/j.1526-4610.2011.01934.x","volume":"51","author":"JM Cohen","year":"2011","unstructured":"Cohen JM, Bigal ME, Newman LC (2011) Migraine and vestibular symptoms\u2013identifying clinical features that predict \u201cvestibular migraine\u201d. Headache 51(9):1393\u20131397. https:\/\/doi.org\/10.1111\/j.1526-4610.2011.01934.x","journal-title":"Headache"},{"issue":"6","key":"10061_CR4","doi-asserted-by":"publisher","first-page":"300","DOI":"10.1111\/j.1526-4610.1992.hed3206300.x","volume":"32","author":"FM Cutrer","year":"1992","unstructured":"Cutrer FM, Baloh RW (1992) Migraine-associated dizziness. Headache 32(6):300\u2013304. https:\/\/doi.org\/10.1111\/j.1526-4610.1992.hed3206300.x","journal-title":"Headache"},{"issue":"10","key":"10061_CR5","doi-asserted-by":"publisher","first-page":"883","DOI":"10.1007\/s004150050478","volume":"246","author":"M Dieterich","year":"1999","unstructured":"Dieterich M, Brandt T (1999) Episodic vertigo related to migraine (90 cases): vestibular migraine? J Neurol 246(10):883\u2013892. https:\/\/doi.org\/10.1007\/s004150050478","journal-title":"J Neurol"},{"key":"10061_CR6","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1111\/nyas.12645","volume":"1343","author":"JM Furman","year":"2015","unstructured":"Furman JM, Balaban CD (2015) Vestibular migraine. Ann NY Acad Sci 1343:90\u201396. https:\/\/doi.org\/10.1111\/nyas.12645","journal-title":"Ann NY Acad Sci"},{"issue":"7","key":"10061_CR7","doi-asserted-by":"publisher","first-page":"706","DOI":"10.1016\/S1474-4422(13)70107-8","volume":"12","author":"JM Furman","year":"2013","unstructured":"Furman JM, Marcus DA, Balaban CD (2013) Vestibular migraine: clinical aspects and pathophysiology. Lancet Neurol 12(7):706\u2013715. https:\/\/doi.org\/10.1016\/S1474-4422(13)70107-8","journal-title":"Lancet Neurol"},{"issue":"Pt 4","key":"10061_CR8","doi-asserted-by":"publisher","first-page":"1123","DOI":"10.1093\/brain\/107.4.1123","volume":"107","author":"A Kayan","year":"1984","unstructured":"Kayan A, Hood JD (1984) Neuro-otological manifestations of migraine. Brain 107(Pt 4):1123\u20131142. https:\/\/doi.org\/10.1093\/brain\/107.4.1123","journal-title":"Brain"},{"issue":"3","key":"10061_CR9","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1016\/j.anl.2017.01.014","volume":"44","author":"AP O'Connell Ferster","year":"2017","unstructured":"O'Connell Ferster AP, Priesol AJ, Isildak H (2017) The clinical manifestations of vestibular migraine: a review. Auris Nasus Larynx 44(3):249\u2013252. https:\/\/doi.org\/10.1016\/j.anl.2017.01.014","journal-title":"Auris Nasus Larynx"},{"key":"10061_CR10","doi-asserted-by":"publisher","first-page":"755","DOI":"10.1016\/S0072-9752(10)97062-0","volume":"97","author":"M Strupp","year":"2010","unstructured":"Strupp M, Versino M, Brandt T (2010) Vestibular migraine. Handb Clin Neurol 97:755\u2013771. https:\/\/doi.org\/10.1016\/S0072-9752(10)97062-0","journal-title":"Handb Clin Neurol"},{"key":"10061_CR11","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-85729-591-0","volume-title":"Vertigo and dizziness: common complaints","author":"T Brandt","year":"2013","unstructured":"Brandt T, Dieterich M, Strupp M (2013) Vertigo and dizziness: common complaints, 2nd edn. Springer, London","edition":"2"},{"issue":"4","key":"10061_CR12","doi-asserted-by":"publisher","first-page":"167","DOI":"10.3233\/VES-2012-0453","volume":"22","author":"T Lempert","year":"2012","unstructured":"Lempert T, Olesen J, Furman J, Waterston J, Seemungal B, Carey J, Bisdorff A, Versino M, Evers S, Newman-Toker D (2012) Vestibular migraine: diagnostic criteria. J Vestib Res 22(4):167\u2013172. https:\/\/doi.org\/10.3233\/VES-2012-0453","journal-title":"J Vestib Res"},{"issue":"1","key":"10061_CR13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3233\/VES-150549","volume":"25","author":"JA Lopez-Escamez","year":"2015","unstructured":"Lopez-Escamez JA, Carey J, Chung WH, Goebel JA, Magnusson M, Mandala M, Newman-Toker DE, Strupp M, Suzuki M, Trabalzini F, Bisdorff A, Classification Committee of the Barany S, Japan Society for Equilibrium R, European Academy of O, Neurotology, Equilibrium Committee of the American Academy of O-H, Neck S, Korean Balance S (2015) Diagnostic criteria for Meniere\u2019s disease. J Vestib Res 25(1):1\u20137","journal-title":"J Vestib Res"},{"key":"10061_CR14","doi-asserted-by":"publisher","first-page":"265","DOI":"10.3389\/fneur.2014.00265","volume":"5","author":"JA Lopez-Escamez","year":"2014","unstructured":"Lopez-Escamez JA, Dlugaiczyk J, Jacobs J, Lempert T, Teggi R, von Brevern M, Bisdorff A (2014) Accompanying symptoms overlap during attacks in Meniere\u2019s disease and vestibular migraine. Front Neurol 5:265. https:\/\/doi.org\/10.3389\/fneur.2014.00265","journal-title":"Front Neurol"},{"issue":"7","key":"10061_CR15","doi-asserted-by":"publisher","first-page":"1235","DOI":"10.1097\/MAO.0b013e31825d644a","volume":"33","author":"BA Neff","year":"2012","unstructured":"Neff BA, Staab JP, Eggers SD, Carlson ML, Schmitt WR, Van Abel KM, Worthington DK, Beatty CW, Driscoll CL, Shepard NT (2012) Auditory and vestibular symptoms and chronic subjective dizziness in patients with Meniere's disease, vestibular migraine, and Meniere's disease with concomitant vestibular migraine. Otol Neurotol 33(7):1235\u20131244. https:\/\/doi.org\/10.1097\/MAO.0b013e31825d644a","journal-title":"Otol Neurotol"},{"issue":"11","key":"10061_CR16","doi-asserted-by":"publisher","first-page":"1700","DOI":"10.1212\/01.wnl.0000036903.22461.39","volume":"59","author":"A Radtke","year":"2002","unstructured":"Radtke A, Lempert T, Gresty MA, Brookes GB, Bronstein AM, Neuhauser H (2002) Migraine and Meniere\u2019s disease: is there a link? Neurology 59(11):1700\u20131704. https:\/\/doi.org\/10.1212\/01.wnl.0000036903.22461.39","journal-title":"Neurology"},{"key":"10061_CR17","volume-title":"Deep learning","author":"I Goodfellow","year":"2016","unstructured":"Goodfellow I, Bengio Y, Courville A (2016) Deep learning. The MIT Press, Cambridge, Massachusetts, Adaptive computation and machine learning"},{"key":"10061_CR18","first-page":"211","volume":"136","author":"M Juhola","year":"2008","unstructured":"Juhola M (2008) On machine learning classification of otoneurological data. Stud Health Technol Inform 136:211\u2013216","journal-title":"Stud Health Technol Inform"},{"key":"10061_CR19","first-page":"579","volume":"169","author":"K Varpa","year":"2011","unstructured":"Varpa K, Joutsijoki H, Iltanen K, Juhola M (2011) Applying one-vs-one and one-vs-all classifiers in k-nearest neighbour method and support vector machines to an otoneurological multi-class problem. Stud Health Technol Inform 169:579\u2013583","journal-title":"Stud Health Technol Inform"},{"key":"10061_CR20","doi-asserted-by":"publisher","first-page":"240","DOI":"10.1016\/j.compbiomed.2016.08.016","volume":"77","author":"TP Exarchos","year":"2016","unstructured":"Exarchos TP, Rigas G, Bibas A, Kikidis D, Nikitas C, Wuyts FL, Ihtijarevic B, Maes L, Cenciarini M, Maurer C, Macdonald N, Bamiou DE, Luxon L, Prasinos M, Spanoudakis G, Koutsouris DD, Fotiadis DI (2016) Mining balance disorders\u2019 data for the development of diagnostic decision support systems. Comput Biol Med 77:240\u2013248. https:\/\/doi.org\/10.1016\/j.compbiomed.2016.08.016","journal-title":"Comput Biol Med"},{"issue":"4","key":"10061_CR21","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1001\/jamaoto.2014.3519","volume":"141","author":"AJ Priesol","year":"2015","unstructured":"Priesol AJ, Cao M, Brodley CE, Lewis RF (2015) Clinical vestibular testing assessed with machine-learning algorithms. JAMA Otolaryngol Head Neck Surg 141(4):364\u2013372. https:\/\/doi.org\/10.1001\/jamaoto.2014.3519","journal-title":"JAMA Otolaryngol Head Neck Surg"},{"key":"10061_CR22","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-94463-0","author":"CC Aggarwal","year":"2018","unstructured":"Aggarwal CC (2018) Neural networks and deep learning. Textbook. https:\/\/doi.org\/10.1007\/978-3-319-94463-0","journal-title":"Textbook"},{"issue":"Suppl 1","key":"10061_CR23","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1007\/s00415-017-8438-7","volume":"264","author":"E Grill","year":"2017","unstructured":"Grill E, Muller T, Becker-Bense S, Gurkov R, Heinen F, Huppert D, Zwergal A, Strobl R (2017) DizzyReg: the prospective patient registry of the German center for vertigo and balance disorders. J Neurol 264(Suppl 1):34\u201336. https:\/\/doi.org\/10.1007\/s00415-017-8438-7","journal-title":"J Neurol"},{"issue":"Suppl 1","key":"10061_CR24","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/s00415-018-8864-1","volume":"265","author":"E Grill","year":"2018","unstructured":"Grill E, Akdal G, Becker-Bense S, Hubinger S, Huppert D, Kentala E, Strobl R, Zwergal A, Celebisoy N (2018) Multicenter data banking in management of dizzy patients: first results from the dizzynet registry project. J Neurol 265(Suppl 1):3\u20138. https:\/\/doi.org\/10.1007\/s00415-018-8864-1","journal-title":"J Neurol"},{"key":"10061_CR25","doi-asserted-by":"crossref","unstructured":"Lopez-Escamez JA, Carey J, Chung WH, Goebel JA, Magnusson M, Mandala M, Newman-Toker DE, Strupp M, Suzuki M, Trabalzini F, Bisdorff A (2016) [Diagnostic criteria for Meniere\u2019s disease. Consensus document of the Barany Society, the Japan Society for Equilibrium Research, the European Academy of Otology and Neurotology (EAONO), the American Academy of Otolaryngology-Head and Neck Surgery (AAO-HNS) and the Korean Balance Society]. Acta Otorrinolaringol Esp 67(1):1\u20137. 10.1016\/j.otorri.2015.05.005","DOI":"10.1016\/j.otorri.2015.05.005"},{"issue":"12","key":"10061_CR26","doi-asserted-by":"publisher","first-page":"e323","DOI":"10.2196\/jmir.5870","volume":"18","author":"W Luo","year":"2016","unstructured":"Luo W, Phung D, Tran T, Gupta S, Rana S, Karmakar C, Shilton A, Yearwood J, Dimitrova N, Ho TB, Venkatesh S, Berk M (2016) Guidelines for developing and reporting machine learning predictive models in biomedical research: a multidisciplinary view. J Med Internet Res 18(12):e323. https:\/\/doi.org\/10.2196\/jmir.5870","journal-title":"J Med Internet Res"},{"issue":"1","key":"10061_CR27","doi-asserted-by":"publisher","first-page":"1","DOI":"10.2478\/jdis-2018-0001","volume":"3","author":"R Rousseau","year":"2018","unstructured":"Rousseau R (2018) The F-measure for research priority. J Data Infor Sci 3(1):1\u201318. https:\/\/doi.org\/10.2478\/jdis-2018-0001","journal-title":"J Data Infor Sci"},{"key":"10061_CR28","unstructured":"Buuren Sv (2018) Flexible imputation of missing data. Chapman and Hall\/CRC interdisciplinary statistics series, Second edition. edn. CRC Press, Taylor and Francis Group, Boca Raton"},{"issue":"3","key":"10061_CR29","first-page":"2011","volume":"1","author":"S van Buuren","year":"2011","unstructured":"van Buuren S, Groothuis-Oudshoorn K (2011) Mice: multivariate imputation by chained equations in R. J Stat Softw 1(3):2011","journal-title":"J Stat Softw"},{"key":"10061_CR30","first-page":"1929","volume":"15","author":"NH SrivastavaGeoffrey","year":"2014","unstructured":"SrivastavaGeoffrey NH, Krizhevsky, Alex, Sutskever, Ilya, Salakhutdinov, Ruslan (2014) Dropout: a simple way to prevent neural networks from overfitting. J Mach Learning Res 15:1929\u20131958","journal-title":"J Mach Learning Res"},{"key":"10061_CR31","unstructured":"Erhan D, Courville A, Bengio Y, Vincent P (2010) Why does unsupervised pre-training help deep learning? In: Yee Whye T, Mike T (eds) Proceedings of the thirteenth international conference on artificial intelligence and statistics. Proceedings of Machine Learning Research, PMLR, vol 9, pp 201\u2013208"},{"key":"10061_CR32","unstructured":"Erhan D, Manzagol PA, Bengio Y, Bengio S, Vincent P (2009) The difficulty of training deep architectures and the effect of unsupervised pre-training. In: David van D, Max W (eds) Proceedings of the twelth international conference on artificial intelligence and statistics. Proceedings of Machine Learning Research, PMLR, vol 5, pp 153\u2013160"},{"key":"10061_CR33","unstructured":"Glorot X, Bengio Y (2010) Understanding the difficulty of training deep feedforward neural networks. In: Yee Whye T, Mike T (eds) Proceedings of the thirteenth international conference on artificial intelligence and statistics. Proceedings of Machine Learning Research, PMLR vol 9, pp 249\u2013256"},{"key":"10061_CR34","doi-asserted-by":"crossref","unstructured":"Hastie T, Tibshirani R, Friedman JH (2009) The elements of statistical learning: data mining, inference, and prediction. Springer series in statistics, 2nd edn. Springer, New York, NY","DOI":"10.1007\/978-0-387-84858-7"},{"key":"10061_CR35","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9780511973000","volume-title":"Machine learning : the art and science of algorithms that make sense of data","author":"PA Flach","year":"2012","unstructured":"Flach PA (2012) Machine learning : the art and science of algorithms that make sense of data. Cambridge University Press, Cambridge, New York"},{"issue":"2","key":"10061_CR36","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1159\/000343814","volume":"69","author":"H Neugebauer","year":"2013","unstructured":"Neugebauer H, Adrion C, Glaser M, Strupp M (2013) Long-term changes of central ocular motor signs in patients with vestibular migraine. Eur Neurol 69(2):102\u2013107. https:\/\/doi.org\/10.1159\/000343814","journal-title":"Eur Neurol"},{"issue":"8","key":"10061_CR37","doi-asserted-by":"publisher","first-page":"906","DOI":"10.1177\/0333102411405228","volume":"31","author":"A Radtke","year":"2011","unstructured":"Radtke A, Neuhauser H, von Brevern M, Hottenrott T, Lempert T (2011) Vestibular migraine\u2013validity of clinical diagnostic criteria. Cephalalgia 31(8):906\u2013913. https:\/\/doi.org\/10.1177\/0333102411405228","journal-title":"Cephalalgia"},{"issue":"15","key":"10061_CR38","doi-asserted-by":"publisher","first-page":"1607","DOI":"10.1212\/WNL.0b013e31826e264f","volume":"79","author":"A Radtke","year":"2012","unstructured":"Radtke A, von Brevern M, Neuhauser H, Hottenrott T, Lempert T (2012) Vestibular migraine: long-term follow-up of clinical symptoms and vestibulo-cochlear findings. Neurology 79(15):1607\u20131614. https:\/\/doi.org\/10.1212\/WNL.0b013e31826e264f","journal-title":"Neurology"},{"issue":"Pt 2","key":"10061_CR39","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1093\/brain\/awh351","volume":"128","author":"M von Brevern","year":"2005","unstructured":"von Brevern M, Zeise D, Neuhauser H, Clarke AH, Lempert T (2005) Acute migrainous vertigo: clinical and oculographic findings. Brain 128(Pt 2):365\u2013374. https:\/\/doi.org\/10.1093\/brain\/awh351","journal-title":"Brain"}],"updated-by":[{"DOI":"10.1007\/s00415-020-10293-9","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2020,11,26]],"date-time":"2020-11-26T00:00:00Z","timestamp":1606348800000}}],"container-title":["Journal of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00415-020-10061-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00415-020-10061-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00415-020-10061-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,13]],"date-time":"2021-07-13T00:27:15Z","timestamp":1626136035000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00415-020-10061-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7,13]]},"references-count":39,"journal-issue":{"issue":"S1","published-print":{"date-parts":[[2020,12]]}},"alternative-id":["10061"],"URL":"https:\/\/doi.org\/10.1007\/s00415-020-10061-9","relation":{"correction":[{"id-type":"doi","id":"10.1007\/s00415-020-10293-9","asserted-by":"object"}]},"ISSN":["0340-5354","1432-1459"],"issn-type":[{"value":"0340-5354","type":"print"},{"value":"1432-1459","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,7,13]]},"assertion":[{"value":"7 April 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 June 2020","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"6 July 2020","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 July 2020","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 November 2020","order":5,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Correction","order":6,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The original version of this article unfortunately contained a mistake. The given names and family names were interchanged.","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"None declared.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"Obtained from the Institutional Review Board of the Medical Faculty, University of Munich.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"All authors read and consented to the final version of the manuscript.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"Code is available upon reasonable scientific request.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Code availability"}}]}}