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Dr. Tanaka reports lecturer\u2019s fees from Daiichi-Sankyo, Medico\u2019s Hirata, and Stryker. Dr. Yoshimoto reports lecture\u2019s fees from Takeda Pharmaceutical. Dr. Shiozawa reports no disclosures. Dr. Yamagami reports\u00a0research grants from Bristol-Myers Squibb; lecturer\u2019s fees from Stryker, Terumo, Medtronic, Medico\u2019s Hirata, Johnson and Johnson, Bayer, Daiichi-Sankyo, Bristol-Myers Squibb, Boehringer Ingelheim, Takeda, and Otsuka Pharmaceutical; and membership of the advisory boards for Daiichi-Sankyo and Biomedical Solutions. Dr. Satow reports research funding from CANON Medical System, lecture\u2019s fees from Medtronic and Stryker. Dr. Takahashi reports no disclosures. Dr. Ihara reports lecturer\u2019s fees from Daiichi Sankyo, Eisai, and Bayer, and grant support from Panasonic, Bristol-Myers Squibb, and Otsuka Pharmaceutical. Dr. Koga reports honoraria from Bayer Yakuhin, Bristol-Myers-Squibb, Otsuka, Daiichi-Sankyo, Nippon Boehringer Ingelheim and Takeda, scientific advisory board from Ono, and research supports from Takeda, Daiichi-Sankyo, Nippon Boehringer Ingelheim, Astellas, Pfizer and Shionogi, outside the submitted work. Dr. Kira reports no disclosures. Dr. Toyoda reports lecturer\u2019s fees from Daiichi Sankyo, Boehringer Ingelheim, Bayer, and Bristol-Myers Squibb.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"This study was approved by the ethics committee of the National Cerebral and Cardiovascular Center, Japan (M23-073-7).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}}]}}