{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T15:32:51Z","timestamp":1793201571613,"version":"4.5.0"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","issue":"12","license":[{"start":{"date-parts":[[2021,6,4]],"date-time":"2021-06-04T00:00:00Z","timestamp":1622764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,6,4]],"date-time":"2021-06-04T00:00:00Z","timestamp":1622764800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"name":"National Natural Science Foundation of China National Youth Project","award":["81700862"],"award-info":[{"award-number":["81700862"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Neurol"],"published-print":{"date-parts":[[2021,12]]},"DOI":"10.1007\/s00415-021-10609-3","type":"journal-article","created":{"date-parts":[[2021,6,4]],"date-time":"2021-06-04T09:03:03Z","timestamp":1622797383000},"page":"4874-4881","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Comparison of the retinal vascular network and structure in patients with optic neuritis associated with myelin oligodendrocyte glycoprotein or aquaporin-4 antibodies: an optical coherence tomography angiography study"],"prefix":"10.1007","volume":"268","author":[{"given":"Jian","family":"Yu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongheng","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingzi","family":"ZhangBao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Zong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Quan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,6,4]]},"reference":[{"key":"10609_CR1","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1016\/j.jns.2016.06.036","volume":"367","author":"H Masuda","year":"2016","unstructured":"Masuda H, Mori M, Uzawa A, Muto M, Uchida T, Ohtani R, Akiba R, Yokouchi H, Yamamoto S, Kuwabara S (2016) Recovery from optic neuritis attack in neuromyelitis optica spectrum disorder and multiple sclerosis. J Neurol Sci 367:375\u2013379. https:\/\/doi.org\/10.1016\/j.jns.2016.06.036","journal-title":"J Neurol Sci"},{"key":"10609_CR2","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/j.preteyeres.2013.03.001","volume":"36","author":"MH Levin","year":"2013","unstructured":"Levin MH, Bennett JL, Verkman AS (2013) Optic neuritis in neuromyelitis optica. Prog Retin Eye Res 36:159\u2013171. https:\/\/doi.org\/10.1016\/j.preteyeres.2013.03.001","journal-title":"Prog Retin Eye Res"},{"key":"10609_CR3","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.jneuroim.2016.11.010","volume":"302","author":"J ZhangBao","year":"2017","unstructured":"ZhangBao J, Zhou L, Li X, Cai T, Lu J, Lu C, Zhao C, Quan C (2017) The clinical characteristics of AQP4 antibody positive NMO\/SD in a large cohort of Chinese Han patients. J Neuroimmunol 302:49\u201355. https:\/\/doi.org\/10.1016\/j.jneuroim.2016.11.010","journal-title":"J Neuroimmunol"},{"issue":"4","key":"10609_CR4","doi-asserted-by":"publisher","first-page":"e40","DOI":"10.1212\/NXI.0000000000000040","volume":"1","author":"S Ramanathan","year":"2014","unstructured":"Ramanathan S, Reddel SW, Henderson A, Parratt JDE, Barnett M, Gatt PN, Merheb V, Kumaran RA, Pathmanandavel K, Sinmaz N, Ghadiri M, Yiannikas C, Vucic S, Stewart G, Bleasel AF, Booth D, Fung VSC, Dale RC, Brilot F (2014) Antibodies to myelin oligodendrocyte glycoprotein in bilateral and recurrent optic neuritis. Neurol Neuroimmunol Neuroinflamm 1(4):e40. https:\/\/doi.org\/10.1212\/NXI.0000000000000040","journal-title":"Neurol Neuroimmunol Neuroinflamm"},{"key":"10609_CR5","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-016-0720-6","author":"F Pache","year":"2016","unstructured":"Pache F, Zimmermann H, Mikolajczak J, Schumacher S, Lacheta A, Oertel FC, Bellmann-Strobl J, Jarius S, Wildemann B, Reindl M, Waldman A, Soelberg K, Asgari N, Ringelstein M, Aktas O, Gross N, Buttmann M, Ach T, Ruprecht K, Paul F, Brandt AU (2016) MOG-IgG in NMO and related disorders: a multicenter study of 50 patients. Part 4: Afferent visual system damage after optic neuritis in MOG-IgG-seropositive versus AQP4-IgG-seropositive patients. J Neuroinflamm. https:\/\/doi.org\/10.1186\/s12974-016-0720-6","journal-title":"J Neuroinflamm"},{"key":"10609_CR6","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.jneuroim.2017.01.007","volume":"305","author":"L Zhou","year":"2017","unstructured":"Zhou L, Huang Y, Li H, Fan J, Zhangbao J, Yu H, Li Y, Lu J, Zhao C, Lu C, Wang M, Quan C (2017) MOG-antibody associated demyelinating disease of the CNS: A clinical and pathological study in Chinese Han patients. J Neuroimmunol 305:19\u201328. https:\/\/doi.org\/10.1016\/j.jneuroim.2017.01.007","journal-title":"J Neuroimmunol"},{"key":"10609_CR7","doi-asserted-by":"publisher","DOI":"10.1177\/1352458519864928","author":"ES Sotirchos","year":"2019","unstructured":"Sotirchos ES, Filippatou A, Fitzgerald KC, Salama S, Pardo S, Wang J, Ogbuokiri E, Cowley NJ, Pellegrini N, Murphy OC, Mealy MA, Prince JL, Levy M, Calabresi PA, Saidha S (2019) Aquaporin-4 IgG seropositivity is associated with worse visual outcomes after optic neuritis than MOG-IgG seropositivity and multiple sclerosis, independent of macular ganglion cell layer thinning. Mult Scler J. https:\/\/doi.org\/10.1177\/1352458519864928","journal-title":"Mult Scler J"},{"issue":"12","key":"10609_CR8","doi-asserted-by":"publisher","first-page":"3127","DOI":"10.1364\/BOE.3.003127","volume":"3","author":"Y Jia","year":"2012","unstructured":"Jia Y, Morrison JC, Tokayer J, Tan O, Lombardi L, Baumann B, Lu CD, Choi W, Fujimoto JG, Huang D (2012) Quantitative OCT angiography of optic nerve head blood flow. Biomed Opt Exp 3(12):3127\u20133137. https:\/\/doi.org\/10.1364\/BOE.3.003127","journal-title":"Biomed Opt Exp"},{"issue":"4","key":"10609_CR9","doi-asserted-by":"publisher","first-page":"578","DOI":"10.1016\/j.ophtha.2017.10.029","volume":"125","author":"A Yarmohammadi","year":"2018","unstructured":"Yarmohammadi A, Zangwill LM, Manalastas P, Fuller NJ, Diniz-Filho A, Saunders LJ, Suh MH, Hasenstab K, Weinreb RN (2018) Peripapillary and macular vessel density in patients with primary open-angle glaucoma and unilateral visual field loss. Ophthalmology 125(4):578\u2013587. https:\/\/doi.org\/10.1016\/j.ophtha.2017.10.029","journal-title":"Ophthalmology"},{"issue":"10","key":"10609_CR10","doi-asserted-by":"publisher","first-page":"1368","DOI":"10.1136\/bjophthalmol-2013-304547","volume":"98","author":"X Wang","year":"2014","unstructured":"Wang X, Jia Y, Spain R, Potsaid B, Liu JJ, Baumann B, Hornegger J, Fujimoto JG, Wu Q, Huang D (2014) Optical coherence tomography angiography of optic nerve head and parafovea in multiple sclerosis. Br J Ophthalmol 98(10):1368\u20131373. https:\/\/doi.org\/10.1136\/bjophthalmol-2013-304547","journal-title":"Br J Ophthalmol"},{"issue":"2","key":"10609_CR11","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1177\/1352458517750009","volume":"25","author":"N Feucht","year":"2019","unstructured":"Feucht N, Maier M, Lepennetier G, Pettenkofer M, Wetzlmair C, Daltrozzo T, Scherm P, Zimmer C, Hoshi M, Hemmer B, Korn T, Knier B (2019) Optical coherence tomography angiography indicates associations of the retinal vascular network and disease activity in multiple sclerosis. Mult Scler J 25(2):224\u2013234. https:\/\/doi.org\/10.1177\/1352458517750009","journal-title":"Mult Scler J"},{"issue":"6","key":"10609_CR12","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1136\/bjophthalmol-2018-312231","volume":"103","author":"Y Huang","year":"2019","unstructured":"Huang Y, Zhou L, ZhangBao J, Cai T, Wang B, Li X, Wang L, Lu C, Zhao C, Lu J, Quan C, Wang M (2019) Peripapillary and parafoveal vascular network assessment by optical coherence tomography angiography in aquaporin-4 antibody-positive neuromyelitis optica spectrum disorders. Brit J Ophthalmol 103(6):789\u2013796. https:\/\/doi.org\/10.1136\/bjophthalmol-2018-312231","journal-title":"Brit J Ophthalmol"},{"key":"10609_CR13","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/j.msard.2016.11.008","volume":"11","author":"F Schmidt","year":"2017","unstructured":"Schmidt F, Zimmermann H, Mikolajczak J, Oertel FC, Pache F, Weinhold M, Schinzel J, Bellmann-Strobl J, Ruprecht K, Paul F, Brandt AU (2017) Severe structural and functional visual system damage leads to profound loss of vision-related quality of life in patients with neuromyelitis optica spectrum disorders. Mult Scler Relat Disord 11:45\u201350. https:\/\/doi.org\/10.1016\/j.msard.2016.11.008","journal-title":"Mult Scler Relat Disord"},{"issue":"6","key":"10609_CR14","doi-asserted-by":"publisher","first-page":"e157645","DOI":"10.1371\/journal.pone.0157645","volume":"11","author":"C Peng","year":"2016","unstructured":"Peng C, Wang W, Xu Q, Zhao S, Li H, Yang M, Cao S, Zhou H, Wei S (2016) Structural alterations of segmented macular inner layers in aquaporin4-antibody-positive optic neuritis patients in a Chinese population. PLoS ONE 11(6):e157645. https:\/\/doi.org\/10.1371\/journal.pone.0157645","journal-title":"PLoS ONE"},{"key":"10609_CR15","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-019-1521-5","author":"FC Oertel","year":"2019","unstructured":"Oertel FC, Outteryck O, Knier B, Zimmermann H, Borisow N, Bellmann-Strobl J, Blaschek A, Jarius S, Reindl M, Ruprecht K, Meinl E, Hohlfeld R, Paul F, Brandt AU, K\u00fcmpfel T, Havla J (2019) Optical coherence tomography in myelin-oligodendrocyte-glycoprotein antibody-seropositive patients: a longitudinal study. J Neuroinflamm. https:\/\/doi.org\/10.1186\/s12974-019-1521-5","journal-title":"J Neuroinflamm"},{"issue":"4","key":"10609_CR16","doi-asserted-by":"publisher","first-page":"742","DOI":"10.1111\/jnc.13143","volume":"135","author":"B Li","year":"2015","unstructured":"Li B, Freeman RD (2015) Neurometabolic coupling between neural activity, glucose, and lactate in activated visual cortex. J Neurochem 135(4):742\u2013754. https:\/\/doi.org\/10.1111\/jnc.13143","journal-title":"J Neurochem"},{"issue":"4","key":"10609_CR17","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1016\/j.ajo.2006.08.009","volume":"142","author":"F Costello","year":"2006","unstructured":"Costello F, Coupland S, Hodge W, Lorello GR, Koroluk J, Pan YI, Freedman MS, Zackon DH, Kardon RH (2006) Quantifying axonal loss after optic neuritis with optical coherence tomography. Am J Ophthalmol 142(4):715. https:\/\/doi.org\/10.1016\/j.ajo.2006.08.009","journal-title":"Am J Ophthalmol"},{"issue":"6","key":"10609_CR18","doi-asserted-by":"publisher","first-page":"809","DOI":"10.1006\/exer.1997.0388","volume":"65","author":"T FitzGibbon","year":"1997","unstructured":"FitzGibbon T, Nestorovski Z (1997) Morphological consequences of myelination in the human retina. Exp Eye Res 65(6):809\u2013819. https:\/\/doi.org\/10.1006\/exer.1997.0388","journal-title":"Exp Eye Res"},{"issue":"9451","key":"10609_CR19","doi-asserted-by":"publisher","first-page":"2106","DOI":"10.1016\/S0140-6736(04)17551-X","volume":"364","author":"VA Lennon","year":"2004","unstructured":"Lennon VA, Wingerchuk DM, Kryzer TJ, Pittock SJ, Lucchinetti CF, Fujihara K, Nakashima I, Weinshenker BG (2004) A serum autoantibody marker of neuromyelitis optica: distinction from multiple sclerosis. Lancet 364(9451):2106\u20132112. https:\/\/doi.org\/10.1016\/S0140-6736(04)17551-X","journal-title":"Lancet"},{"issue":"4","key":"10609_CR20","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1084\/jem.20050304","volume":"202","author":"VA Lennon","year":"2005","unstructured":"Lennon VA, Kryzer TJ, Pittock SJ, Verkman AS, Hinson SR (2005) IgG marker of optic-spinal multiple sclerosis binds to the aquaporin-4 water channel. J Exp Med 202(4):473\u2013477. https:\/\/doi.org\/10.1084\/jem.20050304","journal-title":"J Exp Med"},{"issue":"4","key":"10609_CR21","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1002\/ana.24608","volume":"79","author":"M Hokari","year":"2016","unstructured":"Hokari M, Yokoseki A, Arakawa M, Saji E, Yanagawa K, Yanagimura F, Toyoshima Y, Okamoto K, Ueki S, Hatase T, Ohashi R, Fukuchi T, Akazawa K, Yamada M, Kakita A, Takahashi H, Nishizawa M, Kawachi I (2016) Clinicopathological features in anterior visual pathway in neuromyelitis optica. Ann Neurol 79(4):605\u2013624. https:\/\/doi.org\/10.1002\/ana.24608","journal-title":"Ann Neurol"},{"issue":"13","key":"10609_CR22","doi-asserted-by":"publisher","first-page":"2877","DOI":"10.1002\/jnr.22437","volume":"88","author":"T Pannicke","year":"2010","unstructured":"Pannicke T, Wurm A, Iandiev I, Hollborn M, Linnertz R, Binder DK, Kohen L, Wiedemann P, Steinhauser C, Reichenbach A, Bringmann A (2010) Deletion of aquaporin-4 renders retinal glial cells more susceptible to osmotic stress. J Neurosci Res 88(13):2877\u20132888. https:\/\/doi.org\/10.1002\/jnr.22437","journal-title":"J Neurosci Res"},{"issue":"45","key":"10609_CR23","doi-asserted-by":"publisher","first-page":"15715","DOI":"10.1523\/JNEUROSCI.2841-12.2012","volume":"32","author":"W Shen","year":"2012","unstructured":"Shen W, Fruttiger M, Zhu L, Chung SH, Barnett NL, Kirk JK, Lee S, Coorey NJ, Killingsworth M, Sherman LS, Gillies MC (2012) Conditional Mullercell ablation causes independent neuronal and vascular pathologies in a novel transgenic model. J Neurosci 32(45):15715\u201315727. https:\/\/doi.org\/10.1523\/JNEUROSCI.2841-12.2012","journal-title":"J Neurosci"}],"container-title":["Journal of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00415-021-10609-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00415-021-10609-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00415-021-10609-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,3]],"date-time":"2021-11-03T04:49:12Z","timestamp":1635914952000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00415-021-10609-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6,4]]},"references-count":23,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2021,12]]}},"alternative-id":["10609"],"URL":"https:\/\/doi.org\/10.1007\/s00415-021-10609-3","relation":{},"ISSN":["0340-5354","1432-1459"],"issn-type":[{"value":"0340-5354","type":"print"},{"value":"1432-1459","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6,4]]},"assertion":[{"value":"15 January 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 May 2021","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 May 2021","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 June 2021","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no proprietary or commercial interests regarding any of the content discussed in this article.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"The study was approved by the Ethics Committee of the Eye and ENT Hospital of Fudan University.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}}]}}