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Dr. Katz has served on speaker\u2019s bureaus and advisory boards for Biogen, EMD-Serono, Genentech, Novartis, and Sanofi-Genzyme. Dr. Houtchens has received consulting fees from Biogen, EMD Serono Novartis, and Genentech, and research support from Biogen, Genentech, and Sanofi-Genzyme. Dr. Edwards has received fees for speaking and consulting from Biogen and EMD Serono and research grant support from Biogen, EMD Serono, Genentech, Novartis, and Sanofi-Genzyme. Dr. Bakshi has received consulting fees from EMD Serono and research support from BMS\/Celgene and EMD Serono. The other authors have nothing to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1964, as revised in 2013. Permission was obtained from all patients to be included in this report.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}