{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T13:35:21Z","timestamp":1772544921893,"version":"3.50.1"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2021,10,7]],"date-time":"2021-10-07T00:00:00Z","timestamp":1633564800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,10,7]],"date-time":"2021-10-07T00:00:00Z","timestamp":1633564800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81801272"],"award-info":[{"award-number":["81801272"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004829","name":"Department of Science and Technology of Sichuan Province","doi-asserted-by":"publisher","award":["2018HH0077"],"award-info":[{"award-number":["2018HH0077"]}],"id":[{"id":"10.13039\/501100004829","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["2018SCU12029"],"award-info":[{"award-number":["2018SCU12029"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013365","name":"West China Hospital, Sichuan University","doi-asserted-by":"publisher","award":["2018HXBH085"],"award-info":[{"award-number":["2018HXBH085"]}],"id":[{"id":"10.13039\/501100013365","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Neurol"],"published-print":{"date-parts":[[2022,5]]},"DOI":"10.1007\/s00415-021-10817-x","type":"journal-article","created":{"date-parts":[[2021,10,7]],"date-time":"2021-10-07T04:56:07Z","timestamp":1633582567000},"page":"2503-2512","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Brain network topology and future development of freezing of gait in Parkinson\u2019s disease: a longitudinal study"],"prefix":"10.1007","volume":"269","author":[{"given":"Nannan","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Du","family":"Lei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiaxin","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xueling","family":"Suo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junying","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liren","family":"Duan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chaolan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiyong","family":"Gong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0373-6035","authenticated-orcid":false,"given":"Rong","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,10,7]]},"reference":[{"key":"10817_CR1","doi-asserted-by":"publisher","first-page":"734","DOI":"10.1016\/S1474-4422(11)70143-0","volume":"10","author":"JG Nutt","year":"2011","unstructured":"Nutt JG, Bloem BR, Giladi N et al (2011) Freezing of gait: moving forward on a mysterious clinical phenomenon. Lancet Neurol 10:734\u2013744. https:\/\/doi.org\/10.1016\/S1474-4422(11)70143-0","journal-title":"Lancet Neurol"},{"key":"10817_CR2","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-021-10685-5","author":"WS Zhang","year":"2021","unstructured":"Zhang WS, Gao C, Tan YY et al (2021) Prevalence of freezing of gait in Parkinson\u2019s disease: a systematic review and meta-analysis. J Neurol. https:\/\/doi.org\/10.1007\/s00415-021-10685-5","journal-title":"J Neurol"},{"key":"10817_CR3","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1016\/j.parkreldis.2017.10.013","volume":"46","author":"Y Okuma","year":"2018","unstructured":"Okuma Y, Silva de Lima AL, Fukae J et al (2018) A prospective study of falls in relation to freezing of gait and response fluctuations in Parkinson\u2019s disease. Parkinsonism Relat Disord 46:30\u201335. https:\/\/doi.org\/10.1016\/j.parkreldis.2017.10.013","journal-title":"Parkinsonism Relat Disord"},{"key":"10817_CR4","doi-asserted-by":"publisher","first-page":"768","DOI":"10.1016\/s1474-4422(15)00041-1","volume":"14","author":"J Nonnekes","year":"2015","unstructured":"Nonnekes J, Snijders AH, Nutt JG et al (2015) Freezing of gait: a practical approach to management. Lancet Neurol 14:768\u2013778. https:\/\/doi.org\/10.1016\/s1474-4422(15)00041-1","journal-title":"Lancet Neurol"},{"key":"10817_CR5","doi-asserted-by":"publisher","DOI":"10.1080\/00207454.2020.1837802","author":"R Prajapati","year":"2020","unstructured":"Prajapati R, Emerson IA (2020) Construction and analysis of brain networks from different neuroimaging techniques. Int J Neurosci. https:\/\/doi.org\/10.1080\/00207454.2020.1837802","journal-title":"Int J Neurosci"},{"key":"10817_CR6","doi-asserted-by":"publisher","first-page":"1690","DOI":"10.1016\/j.neuroimage.2010.01.002","volume":"50","author":"M Mennes","year":"2010","unstructured":"Mennes M, Kelly C, Zuo XN et al (2010) Inter-individual differences in resting-state functional connectivity predict task-induced BOLD activity. Neuroimage 50:1690\u20131701. https:\/\/doi.org\/10.1016\/j.neuroimage.2010.01.002","journal-title":"Neuroimage"},{"key":"10817_CR7","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0100291","volume":"9","author":"BW Fling","year":"2014","unstructured":"Fling BW, Cohen RG, Mancini M et al (2014) Functional reorganization of the locomotor network in Parkinson patients with freezing of gait. PLoS ONE 9:e100291. https:\/\/doi.org\/10.1371\/journal.pone.0100291","journal-title":"PLoS ONE"},{"key":"10817_CR8","doi-asserted-by":"publisher","first-page":"1583","DOI":"10.1007\/s00415-016-8174-4","volume":"263","author":"M Wang","year":"2016","unstructured":"Wang M, Jiang S, Yuan Y et al (2016) Alterations of functional and structural connectivity of freezing of gait in Parkinson\u2019s disease. J Neurol 263:1583\u20131592. https:\/\/doi.org\/10.1007\/s00415-016-8174-4","journal-title":"J Neurol"},{"key":"10817_CR9","doi-asserted-by":"publisher","first-page":"119","DOI":"10.1016\/j.neuroscience.2018.01.044","volume":"374","author":"M Gilat","year":"2018","unstructured":"Gilat M, Ehgoetz Martens KA, Miranda-Dom\u00ednguez O et al (2018) Dysfunctional limbic circuitry underlying freezing of gait in Parkinson\u2019s disease. Neuroscience 374:119\u2013132. https:\/\/doi.org\/10.1016\/j.neuroscience.2018.01.044","journal-title":"Neuroscience"},{"key":"10817_CR10","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1016\/j.parkreldis.2012.03.018","volume":"18","author":"A Tessitore","year":"2012","unstructured":"Tessitore A, Amboni M, Esposito F et al (2012) Resting-state brain connectivity in patients with Parkinson\u2019s disease and freezing of gait. Parkinsonism Relat Disord 18:781\u2013787. https:\/\/doi.org\/10.1016\/j.parkreldis.2012.03.018","journal-title":"Parkinsonism Relat Disord"},{"key":"10817_CR11","doi-asserted-by":"publisher","first-page":"5064","DOI":"10.1002\/hbm.22994","volume":"36","author":"E Canu","year":"2015","unstructured":"Canu E, Agosta F, Sarasso E et al (2015) Brain structural and functional connectivity in Parkinson\u2019s disease with freezing of gait. Hum Brain Mapp 36:5064\u20135078. https:\/\/doi.org\/10.1002\/hbm.22994","journal-title":"Hum Brain Mapp"},{"key":"10817_CR12","doi-asserted-by":"publisher","first-page":"1543","DOI":"10.1007\/s11682-019-00085-9","volume":"14","author":"K Bharti","year":"2020","unstructured":"Bharti K, Suppa A, Pietracupa S et al (2020) Aberrant functional connectivity in patients with Parkinson\u2019s disease and freezing of gait: a within- and between-network analysis. Brain Imaging Behav 14:1543\u20131554. https:\/\/doi.org\/10.1007\/s11682-019-00085-9","journal-title":"Brain Imaging Behav"},{"key":"10817_CR13","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awy019","author":"KA Ehgoetz Martens","year":"2018","unstructured":"Ehgoetz Martens KA, Hall JM, Georgiades MJ et al (2018) The functional network signature of heterogeneity in freezing of gait. Brain. https:\/\/doi.org\/10.1093\/brain\/awy019","journal-title":"Brain"},{"key":"10817_CR14","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1093\/brain\/awz314","volume":"143","author":"D Weiss","year":"2020","unstructured":"Weiss D, Schoellmann A, Fox MD et al (2020) Freezing of gait: understanding the complexity of an enigmatic phenomenon. Brain 143:14\u201330. https:\/\/doi.org\/10.1093\/brain\/awz314","journal-title":"Brain"},{"key":"10817_CR15","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1038\/nrn2575","volume":"10","author":"E Bullmore","year":"2009","unstructured":"Bullmore E, Sporns O (2009) Complex brain networks: graph theoretical analysis of structural and functional systems. Nat Rev Neurosci 10:186\u2013198. https:\/\/doi.org\/10.1038\/nrn2575","journal-title":"Nat Rev Neurosci"},{"key":"10817_CR16","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1146\/annurev-clinpsy-040510-143934","volume":"7","author":"ET Bullmore","year":"2011","unstructured":"Bullmore ET, Bassett DS (2011) Brain graphs: graphical models of the human brain connectome. Annu Rev Clin Psychol 7:113\u2013140. https:\/\/doi.org\/10.1146\/annurev-clinpsy-040510-143934","journal-title":"Annu Rev Clin Psychol"},{"key":"10817_CR17","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1097\/WCO.0b013e32833aa567","volume":"23","author":"Y He","year":"2010","unstructured":"He Y, Evans A (2010) Graph theoretical modeling of brain connectivity. Curr Opin Neurol 23:341\u2013350. https:\/\/doi.org\/10.1097\/WCO.0b013e32833aa567","journal-title":"Curr Opin Neurol"},{"key":"10817_CR18","doi-asserted-by":"publisher","first-page":"1059","DOI":"10.1016\/j.neuroimage.2009.10.003","volume":"52","author":"M Rubinov","year":"2010","unstructured":"Rubinov M, Sporns O (2010) Complex network measures of brain connectivity: uses and interpretations. Neuroimage 52:1059\u20131069. https:\/\/doi.org\/10.1016\/j.neuroimage.2009.10.003","journal-title":"Neuroimage"},{"key":"10817_CR19","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevLett.87.198701","volume":"87","author":"V Latora","year":"2001","unstructured":"Latora V, Marchiori M (2001) Efficient behavior of small-world networks. Phys Rev Lett 87:198701. https:\/\/doi.org\/10.1103\/PhysRevLett.87.198701","journal-title":"Phys Rev Lett"},{"key":"10817_CR20","doi-asserted-by":"publisher","first-page":"1353","DOI":"10.1007\/s00415-018-8846-3","volume":"265","author":"JM Hall","year":"2018","unstructured":"Hall JM, Shine JM, Ehgoetz Martens KA et al (2018) Alterations in white matter network topology contribute to freezing of gait in Parkinson\u2019s disease. J Neurol 265:1353\u20131364. https:\/\/doi.org\/10.1007\/s00415-018-8846-3","journal-title":"J Neurol"},{"key":"10817_CR21","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1016\/j.parkreldis.2019.02.036","volume":"63","author":"I Maidan","year":"2019","unstructured":"Maidan I, Jacob Y, Giladi N et al (2019) Altered organization of the dorsal attention network is associated with freezing of gait in Parkinson\u2019s disease. Parkinsonism Relat Disord 63:77\u201382. https:\/\/doi.org\/10.1016\/j.parkreldis.2019.02.036","journal-title":"Parkinsonism Relat Disord"},{"key":"10817_CR22","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2020.580564","volume":"12","author":"X Ruan","year":"2020","unstructured":"Ruan X, Li Y, Li E et al (2020) Impaired topographical organization of functional brain networks in Parkinson\u2019s disease patients with freezing of gait. Front Aging Neurosci 12:580564. https:\/\/doi.org\/10.3389\/fnagi.2020.580564","journal-title":"Front Aging Neurosci"},{"key":"10817_CR23","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2021.135970","volume":"759","author":"N Li","year":"2021","unstructured":"Li N, Suo X, Zhang J et al (2021) Disrupted functional brain network topology in Parkinson\u2019s disease patients with freezing of gait. Neurosci Lett 759:135970. https:\/\/doi.org\/10.1016\/j.neulet.2021.135970","journal-title":"Neurosci Lett"},{"key":"10817_CR24","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2020.582079","volume":"14","author":"M Guo","year":"2020","unstructured":"Guo M, Ren Y, Yu H et al (2020) Alterations in degree centrality and functional connectivity in Parkinson\u2019s disease patients with freezing of gait: a resting-state functional magnetic resonance imaging study. Front Neurosci 14:582079. https:\/\/doi.org\/10.3389\/fnins.2020.582079","journal-title":"Front Neurosci"},{"key":"10817_CR25","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1136\/jnnp.55.3.181","volume":"55","author":"AJ Hughes","year":"1992","unstructured":"Hughes AJ, Daniel SE, Kilford L et al (1992) Accuracy of clinical diagnosis of idiopathic Parkinson\u2019s disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry 55:181\u2013184. https:\/\/doi.org\/10.1136\/jnnp.55.3.181","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10817_CR26","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1007\/s12311-018-0988-4","volume":"18","author":"K Bharti","year":"2019","unstructured":"Bharti K, Suppa A, Pietracupa S et al (2019) Abnormal cerebellar connectivity patterns in patients with Parkinson\u2019s disease and freezing of gait. Cerebellum (London, England) 18:298\u2013308. https:\/\/doi.org\/10.1007\/s12311-018-0988-4","journal-title":"Cerebellum (London, England)"},{"key":"10817_CR27","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1016\/j.jns.2018.01.021","volume":"387","author":"C Zhou","year":"2018","unstructured":"Zhou C, Zhong X, Yang Y et al (2018) Alterations of regional homogeneity in freezing of gait in Parkinson\u2019s disease. J Neurol Sci 387:54\u201359. https:\/\/doi.org\/10.1016\/j.jns.2018.01.021","journal-title":"J Neurol Sci"},{"key":"10817_CR28","doi-asserted-by":"publisher","first-page":"2649","DOI":"10.1002\/mds.23429","volume":"25","author":"CL Tomlinson","year":"2010","unstructured":"Tomlinson CL, Stowe R, Patel S et al (2010) Systematic review of levodopa dose equivalency reporting in Parkinson\u2019s disease. Mov Disord 25:2649\u20132653. https:\/\/doi.org\/10.1002\/mds.23429","journal-title":"Mov Disord"},{"key":"10817_CR29","doi-asserted-by":"publisher","first-page":"386","DOI":"10.3389\/fnhum.2015.00386","volume":"9","author":"J Wang","year":"2015","unstructured":"Wang J, Wang X, Xia M et al (2015) GRETNA: a graph theoretical network analysis toolbox for imaging connectomics. Front Hum Neurosci 9:386. https:\/\/doi.org\/10.3389\/fnhum.2015.00386","journal-title":"Front Hum Neurosci"},{"key":"10817_CR30","doi-asserted-by":"publisher","first-page":"3270","DOI":"10.1152\/jn.90777.2008","volume":"101","author":"MD Fox","year":"2009","unstructured":"Fox MD, Zhang D, Snyder AZ et al (2009) The global signal and observed anticorrelated resting state brain networks. J Neurophysiol 101:3270\u20133283. https:\/\/doi.org\/10.1152\/jn.90777.2008","journal-title":"J Neurophysiol"},{"key":"10817_CR31","doi-asserted-by":"publisher","first-page":"334","DOI":"10.1016\/j.biopsych.2011.05.018","volume":"70","author":"J Zhang","year":"2011","unstructured":"Zhang J, Wang J, Wu Q et al (2011) Disrupted brain connectivity networks in drug-naive, first-episode major depressive disorder. Biol Psychiatry 70:334\u2013342. https:\/\/doi.org\/10.1016\/j.biopsych.2011.05.018","journal-title":"Biol Psychiatry"},{"key":"10817_CR32","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.0030017","volume":"3","author":"S Achard","year":"2007","unstructured":"Achard S, Bullmore E (2007) Efficiency and cost of economical brain functional networks. PLoS Comput Biol 3:e17. https:\/\/doi.org\/10.1371\/journal.pcbi.0030017","journal-title":"PLoS Comput Biol"},{"key":"10817_CR33","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1038\/30918","volume":"393","author":"DJ Watts","year":"1998","unstructured":"Watts DJ, Strogatz SH (1998) Collective dynamics of \u201csmall-world\u201d networks. Nature 393:440\u2013442. https:\/\/doi.org\/10.1038\/30918","journal-title":"Nature"},{"key":"10817_CR34","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1007\/s11910-001-0060-4","volume":"1","author":"C Chayer","year":"2001","unstructured":"Chayer C, Freedman M (2001) Frontal lobe functions. Curr Neurol Neurosci Rep 1:547\u2013552. https:\/\/doi.org\/10.1007\/s11910-001-0060-4","journal-title":"Curr Neurol Neurosci Rep"},{"key":"10817_CR35","doi-asserted-by":"publisher","first-page":"1","DOI":"10.14802\/jmd.16062","volume":"10","author":"K Takakusaki","year":"2017","unstructured":"Takakusaki K (2017) Functional neuroanatomy for posture and gait control. J Mov Disord 10:1\u201317. https:\/\/doi.org\/10.14802\/jmd.16062","journal-title":"J Mov Disord"},{"key":"10817_CR36","doi-asserted-by":"publisher","first-page":"1184","DOI":"10.1016\/j.parkreldis.2015.08.009","volume":"21","author":"M Jha","year":"2015","unstructured":"Jha M, Jhunjhunwala K, Sankara BB et al (2015) Neuropsychological and imaging profile of patients with Parkinson\u2019s disease and freezing of gait. Parkinsonism Relat Disord 21:1184\u20131190. https:\/\/doi.org\/10.1016\/j.parkreldis.2015.08.009","journal-title":"Parkinsonism Relat Disord"},{"key":"10817_CR37","doi-asserted-by":"publisher","first-page":"937","DOI":"10.1016\/j.parkreldis.2013.06.002","volume":"19","author":"E Matar","year":"2013","unstructured":"Matar E, Shine JM, Naismith SL et al (2013) Using virtual reality to explore the role of conflict resolution and environmental salience in freezing of gait in Parkinson\u2019s disease. Parkinsonism Relat Disord 19:937\u2013942. https:\/\/doi.org\/10.1016\/j.parkreldis.2013.06.002","journal-title":"Parkinsonism Relat Disord"},{"key":"10817_CR38","doi-asserted-by":"publisher","DOI":"10.1002\/brb3.931","volume":"8","author":"R Ou","year":"2018","unstructured":"Ou R, Wei Q, Cao B et al (2018) Predictors of freezing of gait in Chinese patients with Parkinson\u2019s disease. Brain Behav 8:e00931. https:\/\/doi.org\/10.1002\/brb3.931","journal-title":"Brain Behav"},{"key":"10817_CR39","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1002\/mds.27208","volume":"33","author":"KA Ehgoetz Martens","year":"2018","unstructured":"Ehgoetz Martens KA, Lukasik EL, Georgiades MJ et al (2018) Predicting the onset of freezing of gait: a longitudinal study. Mov Disord 33:128\u2013135. https:\/\/doi.org\/10.1002\/mds.27208","journal-title":"Mov Disord"},{"key":"10817_CR40","doi-asserted-by":"publisher","first-page":"670","DOI":"10.1212\/01.wnl.0000151961.14861.ba","volume":"64","author":"MS Lee","year":"2005","unstructured":"Lee MS, Kim HS, Lyoo CH (2005) \u201cOff\u201d gait freezing and temporal discrimination threshold in patients with Parkinson disease. Neurology 64:670\u2013674. https:\/\/doi.org\/10.1212\/01.wnl.0000151961.14861.ba","journal-title":"Neurology"},{"key":"10817_CR41","doi-asserted-by":"publisher","first-page":"1905","DOI":"10.2147\/ndt.s197879","volume":"15","author":"Y Zhou","year":"2019","unstructured":"Zhou Y, Zhao J, Hou Y et al (2019) Dopaminergic pathway and primary visual cortex are involved in the freezing of gait in Parkinson\u2019s disease: a PET-CT study. Neuropsychiatr Dis Treat 15:1905\u20131914. https:\/\/doi.org\/10.2147\/ndt.s197879","journal-title":"Neuropsychiatr Dis Treat"},{"key":"10817_CR42","doi-asserted-by":"publisher","first-page":"15020","DOI":"10.1038\/npjparkd.2015.20","volume":"1","author":"M Gilat","year":"2015","unstructured":"Gilat M, Shine JM, Walton CC et al (2015) Brain activation underlying turning in Parkinson\u2019s disease patients with and without freezing of gait: a virtual reality fMRI study. NPJ Parkinson\u2019s disease 1:15020. https:\/\/doi.org\/10.1038\/npjparkd.2015.20","journal-title":"NPJ Parkinson's disease"},{"key":"10817_CR43","doi-asserted-by":"publisher","first-page":"e164","DOI":"10.1212\/wnl.0000000000004795","volume":"90","author":"C Barthel","year":"2018","unstructured":"Barthel C, Nonnekes J, van Helvert M et al (2018) The laser shoes: a new ambulatory device to alleviate freezing of gait in Parkinson disease. Neurology 90:e164\u2013e171. https:\/\/doi.org\/10.1212\/wnl.0000000000004795","journal-title":"Neurology"},{"key":"10817_CR44","doi-asserted-by":"publisher","first-page":"914","DOI":"10.1097\/WNR.0b013e32833ce5f1","volume":"21","author":"PM Schweder","year":"2010","unstructured":"Schweder PM, Hansen PC, Green AL et al (2010) Connectivity of the pedunculopontine nucleus in parkinsonian freezing of gait. NeuroReport 21:914\u2013916. https:\/\/doi.org\/10.1097\/WNR.0b013e32833ce5f1","journal-title":"NeuroReport"},{"key":"10817_CR45","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1002\/ana.24845","volume":"81","author":"A Fasano","year":"2017","unstructured":"Fasano A, Laganiere SE, Lam S et al (2017) Lesions causing freezing of gait localize to a cerebellar functional network. Ann Neurol 81:129\u2013141. https:\/\/doi.org\/10.1002\/ana.24845","journal-title":"Ann Neurol"},{"key":"10817_CR46","doi-asserted-by":"publisher","first-page":"2240","DOI":"10.1002\/mds.28243","volume":"35","author":"JH Jung","year":"2020","unstructured":"Jung JH, Kim BH, Chung SJ et al (2020) motor cerebellar connectivity and future development of freezing of gait in de novo Parkinson\u2019s disease. Mov Disord 35:2240\u20132249. https:\/\/doi.org\/10.1002\/mds.28243","journal-title":"Mov Disord"},{"key":"10817_CR47","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1016\/j.parkreldis.2008.08.006","volume":"15","author":"SJ Lewis","year":"2009","unstructured":"Lewis SJ, Barker RA (2009) A pathophysiological model of freezing of gait in Parkinson\u2019s disease. Parkinsonism Relat Disord 15:333\u2013338. https:\/\/doi.org\/10.1016\/j.parkreldis.2008.08.006","journal-title":"Parkinsonism Relat Disord"}],"container-title":["Journal of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00415-021-10817-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00415-021-10817-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00415-021-10817-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,21]],"date-time":"2022-04-21T14:17:09Z","timestamp":1650550629000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00415-021-10817-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,7]]},"references-count":47,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,5]]}},"alternative-id":["10817"],"URL":"https:\/\/doi.org\/10.1007\/s00415-021-10817-x","relation":{},"ISSN":["0340-5354","1432-1459"],"issn-type":[{"value":"0340-5354","type":"print"},{"value":"1432-1459","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,7]]},"assertion":[{"value":"2 April 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 September 2021","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 September 2021","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 October 2021","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"This study was approved by the Ethics Committee of Sichuan University. Written informed consent was obtained from all participants before enrollment and the study was conducted in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}}]}}