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Hanneke E. Hulst serves in the editorial board of MSJ and has received compensation for consulting services or speaker honoraria from Sanofi Genzyme, Biogen Idec, Celgene, and Merck. BV.  Bianca Weinstock-Guttman received honoraria as a speaker and as a consultant for Biogen Idec, Teva Pharmaceuticals, EMD Serono, Genzyme, Sanofi, Novartis and Acorda. Dr Weinstock-Guttman received research funds from Biogen Idec, Teva Pharmaceuticals, EMD Serono, Genzyme, Sanofi, Novartis, and Acorda.  Robert Zivadinov received personal compensation from EMD Serono, Sanofi, Novartis, Bristol Myers Squibb, and Keystone Heart for speaking and consultant fees. He received financial support for research activities from Sanofi, Novartis, Bristol Myers Squibb, Mapi Pharma, Keystone Heart, V-VAWE Medical, Boston Scientific and Protembo.\u00a0Jeroen Geurts is an editor of Multiple Sclerosis Journal and is president of the Netherlands organization for health research and innovation. He has received research support or compensation for consulting services from the Dutch MS Research Foundation, Ammodo, Eurostars-EUREKA, Biogen, Celgene\/BMS, Merck, MedDay, Novartis and Sanofi-Genzyme.  Michael G. Dwyer has received consultant fees from Claret Medical and EMD Serono and research Grant support from Novartis. \ufeffRalph HB Benedict receives research support from Biogen, Bristol Meyers Squibb, Genzyme, Genentech, Novartis, National Institutes of Health, National Multiple Sclerosis Society, and Verasci. Dr. Benedict has received compensation for speaking and consulting services from Immunic Therapeutics, Latin American Committee for Treatment and Research in Multiple Sclerosis, Merck, Novartis, Roche, Sanofi, Biogen, Bristol Meyers Squibb, and EMD Serono, and receives royalties from Psychological Assessment Resources.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"The study protocol was approved by the University at Buffalo Institutional Ethics Review Board.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"All subjects provided written informed consent before participation.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}