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Piramide reports no disclosures; E. Sarasso reports no disclosures; A. Tomic reports no disclosures; M. Svetel reports no disclosures; S. Basaia reports no disclosures; D. Miskovic reports no disclosures; E. Canu has received research supports from the Italian Ministry of Health; I. Petrovi\u0107 has received speaker honoraria from Actavis and Salveo; V. Kosti\u0107 has received speaker honoraria from Roche and Alkaloid; and receives research supports from the Swiss Pharm and Serbian Ministry of Education, Science and Development and Serbian Academy of Sciences and Art; M. Filippi is Editor-in-Chief of the <i>Journal of Neurology<\/i>, Associate Editor of <i>Human Brain Mapping<\/i>, Associate Editor of <i>Radiology<\/i>, and Associate Editor of <i>Neurological Sciences<\/i>; received compensation for consulting services and\/or speaking activities from Alexion, Almirall, Bayer, Biogen, Celgene, Eli Lilly, Genzyme, Merck-Serono, Novartis, Roche, Sanofi, Takeda, and Teva Pharmaceutical Industries; and receives research support from Biogen Idec, Merck-Serono, Novartis, Roche, Teva Pharmaceutical Industries, Italian Ministry of Health, Fondazione Italiana Sclerosi Multipla, and ARiSLA (Fondazione Italiana di Ricerca per la SLA); F. Agosta is Section Editor of <i>NeuroImage: Clinical<\/i>, has received speaker honoraria from Biogen Idec, Novartis, Philips and Roche, and receives or has received research supports from the Italian Ministry of Health, AriSLA (Fondazione Italiana di Ricerca per la SLA), and the European Research Council.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"This study was performed in line with the principles of the Declaration of Helsinki. Local ethical standards committee on human experimentation approved the study protocol and all participants provided written informed consent prior to study inclusion.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical standards"}}]}}