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We sought to determine the prevalence of financial dysfunction in HD, and the demographic and clinical predictors of such impairments.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>We analysed longitudinal data for pre-manifest gene carriers and HD patients from the\u00a0Enroll-HD dataset.\u00a0Financial dysfunction was determined by finance-related items in the Total Functional Capacity (TFC) and Functional Assessment (FA) scales.\u00a0A binary logistical regression model was used to investigate the predictive value of demographic and clinical factors for the development of financial dysfunction.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Financial impairment was found to be common in HD gene carriers, and over half required financial assistance within 5\u00a0years from diagnosis.\u00a0Cognitive impairment, apathy, unemployment and disease severity predicted financial dysfunction in manifest patients. For pre-manifest patients, the predictors were proximity to disease onset and depression.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Loss of financial autonomy is common in HD, and cognitive and psychiatric factors are important in its development. Clinicians must be vigilant to identify patients that may be vulnerable to financial exploitation.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00415-021-10929-4","type":"journal-article","created":{"date-parts":[[2022,2,14]],"date-time":"2022-02-14T19:02:57Z","timestamp":1644865377000},"page":"3501-3510","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Exploring the predictors of financial impairment in Huntington\u2019s disease using the Enroll-HD dataset"],"prefix":"10.1007","volume":"269","author":[{"given":"Kate L.","family":"Harris","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah L.","family":"Mason","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roger A.","family":"Barker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2022,2,14]]},"reference":[{"key":"10929_CR1","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1016\/B978-0-12-411469-2.00019-4","volume-title":"Handbook of the psychology of aging","author":"DC Marson","year":"2016","unstructured":"Marson DC, Kerr DL, Mclaren DG (2016) Financial decision-making and capacity in older adults. 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