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Bonacchi, E. Pagani, and O. Marchesi have nothing to disclose. A. Meani received speaker honoraria from Biogen Idec. M. Filippi is Editor-in-Chief of the <i>Journal of Neurology<\/i> and Associate Editor of <i>Human Brain Mapping<\/i>, <i>Neurological Sciences<\/i>, and <i>Radiology<\/i>; received compensation for consulting services and\/or speaking activities from Almiral, Alexion, Bayer, Biogen, Celgene, Eli Lilly, Genzyme, Merck-Serono, Novartis, Roche, Sanofi, Takeda, and Teva Pharmaceutical Industries; and receives research support from Biogen Idec, Merck-Serono, Novartis, Roche, Teva Pharmaceutical Industries, Italian Ministry of Health, Fondazione Italiana Sclerosi Multipla, and ARiSLA (Fondazione Italiana di Ricerca per la SLA). M.A. Rocca received speaker honoraria from Bayer, Biogen, Bristol Myers Squibb, Celgene, Genzyme, Merck Serono, Novartis, Roche, and Teva, and receives research support from the MS Society of Canada and Fondazione Italiana Sclerosi Multipla.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}]}}