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Cecchetti, S. Basaia, A. Barbieri, R. Cardamone, M.P. Bernasconi, V. Castelnovo, C. Cividini, M. Cursi, M. Vabanesi, M. Impellizzeri, S.M. Lazzarin, G.F. Fanelli, F. Minicucci, G. Giacalone, A. Falini, M. Falautano, P. Rovere-Querini, L. Roveri have nothing to disclose. E. Canu receives or has received research supports form the Italian Ministry of Health. F. Agosta is Associate Editor of NeuroImage: clinical, has received speaker honoraria from Roche and Biogen Idec, and receives or has received research supports from the Italian Ministry of Health, AriSLA (Fondazione Italiana di Ricerca per la SLA), the European Research Council and Foundation Research on Alzheimer Disease. M. Filippi Editor-in-Chief of the Journal of Neurology and Associate Editor of Human Brain Mapping, Neurological Sciences, and Radiology; received compensation for consulting services and\/or speaking activities from Almiral, Alexion, Bayer, Biogen, Celgene, Eli Lilly, Genzyme, Merck-Serono, Novartis, Roche, Sanofi, Takeda, and Teva Pharmaceutical Industries, and receives research support from Biogen Idec, Merck-Serono, Novartis, Roche, Teva Pharmaceutical Industries, Italian Ministry of Health, Fondazione Italiana Sclerosi Multipla, and ARiSLA (Fondazione Italiana di Ricerca per la SLA).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"The study has been approved by the appropriate ethics committee and has, therefore, been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments. All participants provided written informed consent prior to study inclusion.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}