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Over the past 12\u00a0months, BSC has received an unrestricted grant from AbbVie and honoraria from Sunovion and AbbVie. Over the past 12\u00a0months, LVK has received research support from Canadian Health Institutes of Research (CIHR), Michael J. Fox Foundation for Parkinson's Research, Natural Sciences and Engineering Research Council of Canada (NSERC), Ontario Brain Institute, Parkinson Canada, and Toronto General and Western Hospital Foundation; held contracts with ApoPharma and UCB; and, received honoraria from National Institutes of Health (NIH) and Takeda. The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"The manuscript does not contain clinical studies or patient data.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical standards"}}]}}