{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T08:07:29Z","timestamp":1791360449799,"version":"4.3.1"},"reference-count":45,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2022,9,8]],"date-time":"2022-09-08T00:00:00Z","timestamp":1662595200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2022,9,8]],"date-time":"2022-09-08T00:00:00Z","timestamp":1662595200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100006389","name":"University of Geneva","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100006389","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Neurol"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Aims<\/jats:title>\n                <jats:p>Seizures and status epilepticus (SE) are detected in almost a third of the comatose cardiac arrest survivors. As the literature is quite exhaustive regarding SE with motor symptoms in those patients, little is known about nonconvulsive SE (NCSE). Our aim was to compile the evidence from the literature of the frequency and outcome of NCSE in adult patients remaining in coma after resuscitation.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>The medical search PubMed was screened for most relevant articles reporting the emergence and outcome of NCSE in comatose post-resuscitated adult patients.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>We identified 11 cohort studies (four prospective observational, seven retrospective) including 1092 patients with SE in 29\u201396% and NCSE reported in 1\u201320%. EEG evaluation started at a median of 9.5\u00a0h (range 7.5\u201314.8) after cardiac arrest, during sedation and targeted temperature management (TTM). Favorable outcome after NCSE occurred in 24.5%. We found no study reporting EEG to detect or exclude NCSE in patients remaining in coma prior to the initiation of TTM and without sedation withing the first hours after ROSC.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Discussion<\/jats:title>\n                <jats:p>Studies on NCSE after ROSC are scarce and unsystematic, reporting favorable outcome in every fourth patient experiencing NCSE after ROSC. This suggests that NCSE is often overlooked and outcome after NCSE is not always poor. The low data quality does not allow firm conclusions regarding the effects of NCSE on outcome calling for further investigation. In the meantime, clinicians should avoid equating NCSE after ROSC with poor prognosis.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00415-022-11368-5","type":"journal-article","created":{"date-parts":[[2022,9,8]],"date-time":"2022-09-08T16:22:04Z","timestamp":1662654124000},"page":"130-138","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Nonconvulsive status epilepticus following cardiac arrest: overlooked, untreated and misjudged"],"prefix":"10.1007","volume":"270","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7979-0994","authenticated-orcid":false,"given":"Pia","family":"De Stefano","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter W.","family":"Kaplan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herv\u00e9","family":"Quintard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margitta","family":"Seeck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raoul","family":"Sutter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,9,8]]},"reference":[{"key":"11368_CR1","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1161\/cir.0000000000000702","volume":"140","author":"RG Geocadin","year":"2019","unstructured":"Geocadin RG, Callaway CW, Fink EL, Golan E, Greer DM, Ko NU et al (2019) Standards for studies of neurological prognostication in comatose survivors of cardiac arrest: a scientific statement from the American Heart Association. Circulation 140:517\u2013542. https:\/\/doi.org\/10.1161\/cir.0000000000000702","journal-title":"Circulation"},{"key":"11368_CR2","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1016\/j.jacc.2008.08.076","volume":"53","author":"VR Hosmane","year":"2009","unstructured":"Hosmane VR, Mustafa NG, Reddy VK, Reese CL, DiSabatino A, Kolm P et al (2009) Survival and neurologic recovery in patients with ST-segment elevation myocardial infarction resuscitated from cardiac arrest. J Am Coll Cardiol 53:409\u2013415. https:\/\/doi.org\/10.1016\/j.jacc.2008.08.076","journal-title":"J Am Coll Cardiol"},{"key":"11368_CR3","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1016\/j.resuscitation.2006.07.013","volume":"72","author":"V Gorjup","year":"2007","unstructured":"Gorjup V, Radsel P, Kocjancic ST, Erzen D, Noc M (2007) Acute ST-elevation myocardial infarction after successful cardiopulmonary resuscitation. Resuscitation 72:379\u2013385. https:\/\/doi.org\/10.1016\/j.resuscitation.2006.07.013","journal-title":"Resuscitation"},{"key":"11368_CR4","doi-asserted-by":"publisher","first-page":"2452","DOI":"10.1161\/CIRCULATIONAHA.108.190652","volume":"118","author":"RW Neumar","year":"2008","unstructured":"Neumar RW, Nolan JP, Adrie C, Aibiki M, Berg RA, B\u00f6ttiger BW et al (2008) Post-cardiac arrest syndrome. Circulation 118:2452\u20132483. https:\/\/doi.org\/10.1161\/CIRCULATIONAHA.108.190652","journal-title":"Circulation"},{"key":"11368_CR5","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.resuscitation.2021.02.003","volume":"161","author":"GD Perkins","year":"2021","unstructured":"Perkins GD, Graesner JT, Semeraro F, Olasveengen T, Soar J, Lott C et al (2021) European Resuscitation Council Guidelines 2021: executive summary. Resuscitation 161:1\u201360. https:\/\/doi.org\/10.1016\/j.resuscitation.2021.02.003","journal-title":"Resuscitation"},{"key":"11368_CR6","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1016\/j.resuscitation.2022.01.009","volume":"172","author":"JP Nolan","year":"2022","unstructured":"Nolan JP, Sandroni C, Andersen LW, B\u00f6ttiger BW, Cariou A, Cronberg T et al (2022) ERC-ESICM guidelines on temperature control after cardiac arrest in adults. Resuscitation 172:229\u2013236. https:\/\/doi.org\/10.1016\/j.resuscitation.2022.01.009","journal-title":"Resuscitation"},{"key":"11368_CR7","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1007\/s00134-021-06368-4","volume":"47","author":"JP Nolan","year":"2021","unstructured":"Nolan JP, Sandroni C, B\u00f6ttiger BW, Cariou A, Cronberg T, Friberg H et al (2021) European Resuscitation Council and European Society of Intensive Care Medicine guidelines 2021: post-resuscitation care. Intensive Care Med 47:369\u2013421. https:\/\/doi.org\/10.1007\/s00134-021-06368-4","journal-title":"Intensive Care Med"},{"key":"11368_CR8","doi-asserted-by":"publisher","first-page":"255","DOI":"10.1212\/01.wnl.0000265819.36639.e0","volume":"69","author":"AO Rossetti","year":"2007","unstructured":"Rossetti AO, Logroscino G, Liaudet L, Ruffieux C, Ribordy V, Schaller MD et al (2007) Status epilepticus: an independent outcome predictor after cerebral anoxia. Neurology 69:255\u2013260. https:\/\/doi.org\/10.1212\/01.wnl.0000265819.36639.e0","journal-title":"Neurology"},{"key":"11368_CR9","doi-asserted-by":"publisher","first-page":"744","DOI":"10.1212\/01.wnl.0000343006.60851.62","volume":"72","author":"AO Rossetti","year":"2009","unstructured":"Rossetti AO, Oddo M, Liaudet L, Kaplan PW (2009) Predictors of awakening from postanoxic status epilepticus after therapeutic hypothermia. Neurology 72:744\u2013749. https:\/\/doi.org\/10.1212\/01.wnl.0000343006.60851.62","journal-title":"Neurology"},{"key":"11368_CR10","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/j.resuscitation.2016.08.012","volume":"109","author":"E Amorim","year":"2016","unstructured":"Amorim E, Rittenberger JC, Zheng JJ, Westover MB, Baldwin ME, Callaway CW et al (2016) Continuous EEG monitoring enhances multimodal outcome prediction in hypoxic\u2013ischemic brain injury. Resuscitation 109:121\u2013126. https:\/\/doi.org\/10.1016\/j.resuscitation.2016.08.012","journal-title":"Resuscitation"},{"key":"11368_CR11","doi-asserted-by":"publisher","first-page":"1838","DOI":"10.1097\/CCM.0b013e3181eaa1e7","volume":"38","author":"M Rundgren","year":"2010","unstructured":"Rundgren M, Westhall E, Cronberg T, Ros\u00e9n I, Friberg H (2010) Continuous amplitude-integrated electroencephalogram predicts outcome in hypothermia-treated cardiac arrest patients. Crit Care Med 38:1838\u20131844. https:\/\/doi.org\/10.1097\/CCM.0b013e3181eaa1e7","journal-title":"Crit Care Med"},{"key":"11368_CR12","doi-asserted-by":"publisher","first-page":"1124","DOI":"10.1097\/CCM.0b013e318275882f","volume":"41","author":"R Sutter","year":"2013","unstructured":"Sutter R, Stevens RD, Kaplan PW (2013) Continuous electroencephalographic monitoring in critically ill patients. Crit Care Med 41:1124\u20131132. https:\/\/doi.org\/10.1097\/CCM.0b013e318275882f","journal-title":"Crit Care Med"},{"key":"11368_CR13","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1097\/WNP.0000000000000216","volume":"33","author":"R Sutter","year":"2016","unstructured":"Sutter R (2016) Are we prepared to detect subtle and nonconvulsive status epilepticus in critically ill patients? J Clin Neurophysiol 33:25\u201331. https:\/\/doi.org\/10.1097\/WNP.0000000000000216","journal-title":"J Clin Neurophysiol"},{"key":"11368_CR14","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1016\/j.yebeh.2015.04.043","volume":"49","author":"I Dragancea","year":"2015","unstructured":"Dragancea I, Backman S, Westhall E, Rundgren M, Friberg H, Cronberg T (2015) Outcome following postanoxic status epilepticus in patients with targeted temperature management after cardiac arrest. Epilepsy Behav 49:173\u2013177. https:\/\/doi.org\/10.1016\/j.yebeh.2015.04.043","journal-title":"Epilepsy Behav"},{"key":"11368_CR15","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1016\/j.resuscitation.2005.05.019","volume":"68","author":"A Hovland","year":"2006","unstructured":"Hovland A, Nielsen EW, Kl\u00fcver J, Salvesen R (2006) EEG should be performed during induced hypothermia. Resuscitation 68:143\u2013146. https:\/\/doi.org\/10.1016\/j.resuscitation.2005.05.019","journal-title":"Resuscitation"},{"key":"11368_CR16","doi-asserted-by":"publisher","first-page":"1295","DOI":"10.1212\/01.wnl.0000312074.77793.a4","volume":"70","author":"PW Kaplan","year":"2008","unstructured":"Kaplan PW, Morales Y (2008) Status epilepticus: an independent outcome predictor after cerebral anoxia. Neurology 70:1295\u20131296. https:\/\/doi.org\/10.1212\/01.wnl.0000312074.77793.a4","journal-title":"Neurology"},{"key":"11368_CR17","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1212\/01.wnl.0000227183.21314.cd","volume":"67","author":"EFM Wijdicks","year":"2006","unstructured":"Wijdicks EFM, Hijdra A, Young GB, Bassetti CL, Wiebe S (2006) Practice parameter: prediction of outcome in comatose survivors after cardiopulmonary resuscitation (an evidence-based review): Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 67:203\u2013210. https:\/\/doi.org\/10.1212\/01.wnl.0000227183.21314.cd","journal-title":"Neurology"},{"key":"11368_CR18","doi-asserted-by":"publisher","DOI":"10.1001\/archneurol.2010.169","author":"A Neligan","year":"2010","unstructured":"Neligan A, Shorvon SD (2010) Frequency and prognosis of convulsive status epilepticus of different causes. Arch Neurol. https:\/\/doi.org\/10.1001\/archneurol.2010.169","journal-title":"Arch Neurol"},{"key":"11368_CR19","doi-asserted-by":"publisher","first-page":"1845","DOI":"10.1111\/epi.13202","volume":"56","author":"BJ Ruijter","year":"2015","unstructured":"Ruijter BJ, van Putten MJAM, Hofmeijer J (2015) Generalized epileptiform discharges in postanoxic encephalopathy: quantitative characterization in relation to outcome. Epilepsia 56:1845\u20131854. https:\/\/doi.org\/10.1111\/epi.13202","journal-title":"Epilepsia"},{"key":"11368_CR20","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1038\/nrneurol.2016.45","volume":"12","author":"R Sutter","year":"2016","unstructured":"Sutter R, Semmlack S, Kaplan PW (2016) Nonconvulsive status epilepticus in adults\u2014insights into the invisible. Nat Rev Neurol 12:281\u2013293. https:\/\/doi.org\/10.1038\/nrneurol.2016.45","journal-title":"Nat Rev Neurol"},{"key":"11368_CR21","doi-asserted-by":"publisher","DOI":"10.1111\/epi.17319","author":"P de Stefano","year":"2022","unstructured":"de Stefano P, Kaplan PW, Sutter R (2022) Not all rhythmicities and periodicities in coma electroencephalography are fatal\u2014when simplification becomes dangerous. Epilepsia. https:\/\/doi.org\/10.1111\/epi.17319","journal-title":"Epilepsia"},{"key":"11368_CR22","doi-asserted-by":"publisher","first-page":"724","DOI":"10.1056\/NEJMoa2115998","volume":"386","author":"BJ Ruijter","year":"2022","unstructured":"Ruijter BJ, Keijzer HM, Tjepkema-Cloostermans MC, Blans MJ, Beishuizen A, Tromp SC et al (2022) Treating rhythmic and periodic EEG patterns in comatose survivors of cardiac arrest. N Engl J Med 386:724\u2013734. https:\/\/doi.org\/10.1056\/NEJMoa2115998","journal-title":"N Engl J Med"},{"key":"11368_CR23","doi-asserted-by":"publisher","first-page":"910","DOI":"10.1016\/j.ijcard.2014.08.057","volume":"176","author":"T Fukuda","year":"2014","unstructured":"Fukuda T, Matsubara T, Doi K, Fukuda-Ohashi N, Yahagi N (2014) Predictors of favorable and poor prognosis in unwitnessed out-of-hospital cardiac arrest with a non-shockable initial rhythm. Int J Cardiol 176:910\u2013915. https:\/\/doi.org\/10.1016\/j.ijcard.2014.08.057","journal-title":"Int J Cardiol"},{"key":"11368_CR24","doi-asserted-by":"publisher","first-page":"846","DOI":"10.1007\/s00134-014-3252-5","volume":"40","author":"W Bougouin","year":"2014","unstructured":"Bougouin W, Lamhaut L, Marijon E, Jost D, Dumas F, Deye N et al (2014) Characteristics and prognosis of sudden cardiac death in Greater Paris. Intensive Care Med 40:846\u2013854. https:\/\/doi.org\/10.1007\/s00134-014-3252-5","journal-title":"Intensive Care Med"},{"key":"11368_CR25","doi-asserted-by":"publisher","first-page":"644","DOI":"10.3390\/jcm8050644","volume":"8","author":"KS Han","year":"2019","unstructured":"Han KS, Lee SW, Lee EJ, Kim SJ (2019) Prognostic value of the conversion to a shockable rhythm in out-of-hospital cardiac arrest patients with initial non-shockable rhythm. J Clin Med 8:644. https:\/\/doi.org\/10.3390\/jcm8050644","journal-title":"J Clin Med"},{"key":"11368_CR26","doi-asserted-by":"publisher","first-page":"1515","DOI":"10.1111\/epi.13121","volume":"56","author":"E Trinka","year":"2015","unstructured":"Trinka E, Cock H, Hesdorffer D, Rossetti AO, Scheffer IE, Shinnar S et al (2015) A definition and classification of status epilepticus\u2014report of the ILAE Task Force on Classification of Status Epilepticus. Epilepsia 56:1515\u20131523. https:\/\/doi.org\/10.1111\/epi.13121","journal-title":"Epilepsia"},{"key":"11368_CR27","first-page":"155","volume-title":"Brain failure and resuscitation. Resuscitation after brain ischemia","year":"1981","unstructured":"Grenvik ASP (ed) (1981) Brain failure and resuscitation. Resuscitation after brain ischemia. Churchill Livingstone, New York, pp 155\u2013184"},{"key":"11368_CR28","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.resuscitation.2016.09.006","volume":"109","author":"AV Grossestreuer","year":"2016","unstructured":"Grossestreuer AV, Abella BS, Sheak KR, Cinousis MJ, Perman SM, Leary M et al (2016) Inter-rater reliability of post-arrest cerebral performance category (CPC) scores. Resuscitation 109:21\u201324. https:\/\/doi.org\/10.1016\/j.resuscitation.2016.09.006","journal-title":"Resuscitation"},{"key":"11368_CR29","doi-asserted-by":"publisher","DOI":"10.1097\/WNP.0000000000000806","author":"LJ Hirsch","year":"2021","unstructured":"Hirsch LJ, Fong M, Leitinger M, LaRoche S, Beniczky S, Abend NS et al (2021) American Clinical Neurophysiology Society\u2019s Standardized Critical Care EEG Terminology: 2021 version 2021. J Clin Neurophysiol. https:\/\/doi.org\/10.1097\/WNP.0000000000000806","journal-title":"J Clin Neurophysiol"},{"key":"11368_CR30","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1111\/epi.12270","volume":"54","author":"S Beniczky","year":"2013","unstructured":"Beniczky S, Hirsch LJ, Kaplan PW, Pressler R, Bauer G, Aurlien H et al (2013) Unified EEG terminology and criteria for nonconvulsive status epilepticus. Epilepsia 54:28\u201329. https:\/\/doi.org\/10.1111\/epi.12270","journal-title":"Epilepsia"},{"key":"11368_CR31","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1016\/j.yebeh.2015.05.007","volume":"49","author":"M Leitinger","year":"2015","unstructured":"Leitinger M, Beniczky S, Rohracher A, Gardella E, Kalss G, Qerama E et al (2015) Salzburg consensus criteria for non-convulsive status epilepticus\u2014approach to clinical application. Epilepsy Behav 49:158\u2013163. https:\/\/doi.org\/10.1016\/j.yebeh.2015.05.007","journal-title":"Epilepsy Behav"},{"key":"11368_CR32","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1007\/s12028-011-9565-0","volume":"16","author":"JC Rittenberger","year":"2012","unstructured":"Rittenberger JC, Popescu A, Brenner RP, Guyette FX, Callaway CW (2012) Frequency and timing of nonconvulsive status epilepticus in comatose post-cardiac arrest subjects treated with hypothermia. Neurocrit Care 16:114\u2013122. https:\/\/doi.org\/10.1007\/s12028-011-9565-0","journal-title":"Neurocrit Care"},{"key":"11368_CR33","doi-asserted-by":"publisher","first-page":"1255","DOI":"10.23736\/S0375-9393.17.11629-9","volume":"83","author":"C Lettieri","year":"2017","unstructured":"Lettieri C, Devigili G, Pauletto G, Isola M, Rinaldo S, Budai R et al (2017) Post-anoxic status epilepticus: which variable could modify prognosis? A single-center experience. Minerva Anestesiol 83:1255\u20131264. https:\/\/doi.org\/10.23736\/S0375-9393.17.11629-9","journal-title":"Minerva Anestesiol"},{"key":"11368_CR34","doi-asserted-by":"publisher","first-page":"840","DOI":"10.1016\/j.resuscitation.2012.02.015","volume":"83","author":"R Mani","year":"2012","unstructured":"Mani R, Schmitt SE, Mazer M, Putt ME, Gaieski DF (2012) The frequency and timing of epileptiform activity on continuous electroencephalogram in comatose post-cardiac arrest syndrome patients treated with therapeutic hypothermia. Resuscitation 83:840\u2013847. https:\/\/doi.org\/10.1016\/j.resuscitation.2012.02.015","journal-title":"Resuscitation"},{"key":"11368_CR35","doi-asserted-by":"publisher","first-page":"1743","DOI":"10.1212\/01.WNL.0000125184.88797.62","volume":"62","author":"J Claassen","year":"2004","unstructured":"Claassen J, Mayer SA, Kowalski RG, Emerson RG, Hirsch LJ (2004) Detection of electrographic seizures with continuous EEG monitoring in critically ill patients. Neurology 62:1743\u20131748. https:\/\/doi.org\/10.1212\/01.WNL.0000125184.88797.62","journal-title":"Neurology"},{"key":"11368_CR36","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1016\/j.clinph.2017.01.002","volume":"128","author":"S Backman","year":"2017","unstructured":"Backman S, Westhall E, Dragancea I, Friberg H, Rundgren M, Ull\u00e9n S et al (2017) Electroencephalographic characteristics of status epilepticus after cardiac arrest. Clin Neurophysiol 128:681\u2013688. https:\/\/doi.org\/10.1016\/j.clinph.2017.01.002","journal-title":"Clin Neurophysiol"},{"key":"11368_CR37","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1016\/j.resuscitation.2012.11.001","volume":"84","author":"S Legriel","year":"2013","unstructured":"Legriel S, Hilly-Ginoux J, Resche-Rigon M, Merceron S, Pinoteau J, Henry-Lagarrigue M et al (2013) Prognostic value of electrographic postanoxic status epilepticus in comatose cardiac-arrest survivors in the therapeutic hypothermia era. Resuscitation 84:343\u2013350. https:\/\/doi.org\/10.1016\/j.resuscitation.2012.11.001","journal-title":"Resuscitation"},{"key":"11368_CR38","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1007\/s12028-009-9246-4","volume":"11","author":"S Legriel","year":"2009","unstructured":"Legriel S, Bruneel F, Sediri H, Hilly J, Abbosh N, Lagarrigue MH et al (2009) Early EEG monitoring for detecting postanoxic status epilepticus during therapeutic hypothermia: a pilot study. Neurocrit Care 11:338\u2013344. https:\/\/doi.org\/10.1007\/s12028-009-9246-4","journal-title":"Neurocrit Care"},{"key":"11368_CR39","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1080\/14737175.2017.1369880","volume":"17","author":"MO Kinney","year":"2017","unstructured":"Kinney MO, Kaplan PW (2017) An update on the recognition and treatment of non-convulsive status epilepticus in the intensive care unit. Expert Rev Neurother 17:987\u20131002. https:\/\/doi.org\/10.1080\/14737175.2017.1369880","journal-title":"Expert Rev Neurother"},{"key":"11368_CR40","doi-asserted-by":"publisher","first-page":"1660","DOI":"10.1016\/j.clinph.2018.05.016","volume":"129","author":"E Westhall","year":"2018","unstructured":"Westhall E, Ros\u00e9n I, Rundgren M, Bro-Jeppesen J, Kjaergaard J, Hassager C et al (2018) Time to epileptiform activity and EEG background recovery are independent predictors after cardiac arrest. Clin Neurophysiol 129:1660\u20131668. https:\/\/doi.org\/10.1016\/j.clinph.2018.05.016","journal-title":"Clin Neurophysiol"},{"key":"11368_CR41","doi-asserted-by":"publisher","first-page":"2851","DOI":"10.1016\/j.clinph.2021.07.026","volume":"132","author":"LM Willems","year":"2021","unstructured":"Willems LM, Trienekens F, Knake S, Beuchat I, Rosenow F, Schieffer B et al (2021) EEG patterns and their correlations with short- and long-term mortality in patients with hypoxic encephalopathy. Clin Neurophysiol 132:2851\u20132860. https:\/\/doi.org\/10.1016\/j.clinph.2021.07.026","journal-title":"Clin Neurophysiol"},{"key":"11368_CR42","doi-asserted-by":"publisher","first-page":"1955","DOI":"10.1016\/S0140-6736(08)60837-5","volume":"371","author":"KH Polderman","year":"2008","unstructured":"Polderman KH (2008) Induced hypothermia and fever control for prevention and treatment of neurological injuries. Lancet 371:1955\u20131969. https:\/\/doi.org\/10.1016\/S0140-6736(08)60837-5","journal-title":"Lancet"},{"key":"11368_CR43","doi-asserted-by":"publisher","first-page":"1007","DOI":"10.1097\/00000539-199505000-00027","volume":"80","author":"K Leslie","year":"1995","unstructured":"Leslie K, Sessler DI, Bjorksten AR, Moayeri A (1995) Mild hypothermia alters propofol pharmacokinetics and increases the duration of action of atracurium. Anesth Analg 80:1007\u20131014. https:\/\/doi.org\/10.1097\/00000539-199505000-00027","journal-title":"Anesth Analg"},{"key":"11368_CR44","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1007\/s12028-012-9695-z","volume":"17","author":"GM Brophy","year":"2012","unstructured":"Brophy GM, Bell R, Claassen J, Alldredge B, Bleck TP, Glauser T et al (2012) Guidelines for the evaluation and management of status epilepticus. Neurocrit Care 17:3\u201323. https:\/\/doi.org\/10.1007\/s12028-012-9695-z","journal-title":"Neurocrit Care"},{"key":"11368_CR45","doi-asserted-by":"publisher","first-page":"177","DOI":"10.1111\/j.1528-1167.2009.02297.x","volume":"51","author":"G Bauer","year":"2010","unstructured":"Bauer G, Trinka E (2010) Nonconvulsive status epilepticus and coma. Epilepsia 51:177\u2013190. https:\/\/doi.org\/10.1111\/j.1528-1167.2009.02297.x","journal-title":"Epilepsia"}],"container-title":["Journal of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00415-022-11368-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00415-022-11368-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00415-022-11368-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,4]],"date-time":"2023-01-04T17:19:26Z","timestamp":1672852766000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00415-022-11368-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,8]]},"references-count":45,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1]]}},"alternative-id":["11368"],"URL":"https:\/\/doi.org\/10.1007\/s00415-022-11368-5","relation":{},"ISSN":["0340-5354","1432-1459"],"issn-type":[{"value":"0340-5354","type":"print"},{"value":"1432-1459","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,8]]},"assertion":[{"value":"14 August 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 August 2022","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 September 2022","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 September 2022","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Pia De Stefano reports no conflict of interest to declare. Peter W. Kaplan has provided unsponsored grand rounds, published books on electroencephalograph, status epilepticus, and epilepsy for which he received honoraria, has consulted for Cadwell and Ceribell, has been on the board of the American Board of Clinical Neuropsychology, the International Congress of Clinical Neurophysiology, and the American Clinical Neurophysiology Society; and testified on the use of quantitative electroencephalograph (qEEG). He received funding from electroencephalograph, qEEG, Demos, Wiley-Blackwell, and Ceribel. Herv\u00e9 Quintard reports no conflict of interest. Margitta Seeck is shareholder of Epilog NV (Ghent, Belgium). Raoul Sutter received research grants from the Swiss National Foundation (No 320030_169379), the Research Fund of the University Basel, the Scientific Society Basel, and the Bangerter-Rhyner Foundation. He received personal grants from UCBpharma and holds stocks from Novartis, Roche, Alcon, and Johnson&Johnson. Neither of the authors has any conflict of interest to disclose relevant to this paper.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}}]}}