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He has also received travel grants from UCB, Merck and PACTRIMS, and travel awards from ACTRIMS, ECTRIMS and Orebro University. Kevin Tan has received travel grants and compensation from Novartis, Merck, Sanofi, Eisai, Viela Bio and Roche for consulting services. Rachel Wan En Siew, Muhammad Yaaseen Gulam, Janis Siew Noi Tye, Amelia Yun Yi Aw, Thanushiree Sivalingam, Xuejuan Peng, Kok Pin Yong, Seyed Ehsan Saffari, and Yinxia Chao report no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2000. This study was approved by the Institutional Review Board at SingHealth (CIRB number 2020\/2410, 2021\/2222).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Written informed consent was obtained from all patients in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"This content has been made available to all.","name":"free","label":"Free to read"}]}}