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Written consent was obtained from the next of kin or guardian for genetic investigations and publication of anonymized data obtained through clinical characterization and scientific research. This study was performed in accordance with the ethical standards established in the 1964 Declaration of Helsinki. All experimental protocols, including the use of pathological specimens obtained at autopsies for research upon anonymization, were approved by the official ethical institutional review board of the University of Toyama (I2020006).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics standard"}}]}}