{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T03:04:18Z","timestamp":1793070258213,"version":"4.5.0"},"reference-count":68,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T00:00:00Z","timestamp":1697587200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T00:00:00Z","timestamp":1697587200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82230039"],"award-info":[{"award-number":["82230039"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U21A20360"],"award-info":[{"award-number":["U21A20360"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81971082"],"award-info":[{"award-number":["81971082"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Neurol"],"published-print":{"date-parts":[[2024,2]]},"DOI":"10.1007\/s00415-023-12042-0","type":"journal-article","created":{"date-parts":[[2023,10,18]],"date-time":"2023-10-18T02:01:48Z","timestamp":1697594508000},"page":"918-928","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Cognitive impairment associated with cerebellar volume loss in spinocerebellar ataxia type 3"],"prefix":"10.1007","volume":"271","author":[{"given":"Zhi-Xian","family":"Ye","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Bi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang-Liang","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuan-Yu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng-Cheng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin-Yuan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Sen","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ru-Ying","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin-Tong","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Yu","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bi","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wan-Jin","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian-Ping","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7552-5141","authenticated-orcid":false,"given":"Shi-Rui","family":"Gan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"OSCCAR Investigators","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,10,18]]},"reference":[{"key":"12042_CR1","doi-asserted-by":"publisher","first-page":"19538","DOI":"10.1073\/pnas.2002896117","volume":"117","author":"MI Sereno","year":"2020","unstructured":"Sereno MI, Diedrichsen J, Tachrount M, Testa-Silva G, d\u2019Arceuil H, De Zeeuw C (2020) The human cerebellum has almost 80% of the surface area of the neocortex. Proc Natl Acad Sci U S A 117:19538\u201319543","journal-title":"Proc Natl Acad Sci U S A"},{"key":"12042_CR2","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1016\/j.neuron.2013.10.044","volume":"80","author":"RL Buckner","year":"2013","unstructured":"Buckner RL (2013) The cerebellum and cognitive function: 25 years of insight from anatomy and neuroimaging. Neuron 80:807\u2013815","journal-title":"Neuron"},{"key":"12042_CR3","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1146\/annurev-neuro-070918-050258","volume":"42","author":"JD Schmahmann","year":"2019","unstructured":"Schmahmann JD, Guell X, Stoodley CJ, Halko MA (2019) The theory and neuroscience of cerebellar cognition. Annu Rev Neurosci 42:337\u2013364","journal-title":"Annu Rev Neurosci"},{"key":"12042_CR4","doi-asserted-by":"publisher","first-page":"352","DOI":"10.1007\/s12311-011-0260-7","volume":"11","author":"CJ Stoodley","year":"2012","unstructured":"Stoodley CJ (2012) The cerebellum and cognition: evidence from functional imaging studies. Cerebellum 11:352\u2013365","journal-title":"Cerebellum"},{"key":"12042_CR5","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.neurobiolaging.2019.10.026","volume":"89","author":"G Olivito","year":"2020","unstructured":"Olivito G, Serra L, Marra C, Di Domenico C, Caltagirone C, Toniolo S, Cercignani M, Leggio M, Bozzali M (2020) Cerebellar dentate nucleus functional connectivity with cerebral cortex in Alzheimer\u2019s disease and memory: a seed-based approach. Neurobiol Aging 89:32\u201340","journal-title":"Neurobiol Aging"},{"key":"12042_CR6","doi-asserted-by":"publisher","first-page":"910","DOI":"10.1016\/j.brs.2022.06.004","volume":"15","author":"Q Yao","year":"2022","unstructured":"Yao Q, Tang F, Wang Y, Yan Y, Dong L, Wang T, Zhu D, Tian M, Lin X, Shi J (2022) Effect of cerebellum stimulation on cognitive recovery in patients with Alzheimer disease: a randomized clinical trial. Brain Stimul 15:910\u2013920","journal-title":"Brain Stimul"},{"key":"12042_CR7","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1016\/j.parkreldis.2020.09.005","volume":"80","author":"K Kawabata","year":"2020","unstructured":"Kawabata K, Watanabe H, Bagarinao E, Ohdake R, Hara K, Ogura A, Masuda M, Kato T, Tsuboi T, Maesawa S, Katsuno M, Sobue G (2020) Cerebello-basal ganglia connectivity fingerprints related to motor\/cognitive performance in Parkinson\u2019s disease. Parkinsonism Relat Disord 80:21\u201327","journal-title":"Parkinsonism Relat Disord"},{"key":"12042_CR8","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1177\/1352458520922770","volume":"27","author":"G Pasqua","year":"2021","unstructured":"Pasqua G, Tommasin S, Bharti K, Ruggieri S, Petsas N, Piervincenzi C, Pozzilli C, Pantano P (2021) Resting-state functional connectivity of anterior and posterior cerebellar lobes is altered in multiple sclerosis. Mult Scler 27:539\u2013548","journal-title":"Mult Scler"},{"key":"12042_CR9","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1093\/brain\/awx194","volume":"141","author":"HIL Jacobs","year":"2018","unstructured":"Jacobs HIL, Hopkins DA, Mayrhofer HC, Bruner E, van Leeuwen FW, Raaijmakers W, Schmahmann JD (2018) The cerebellum in Alzheimer\u2019s disease: evaluating its role in cognitive decline. Brain 141:37\u201347","journal-title":"Brain"},{"key":"12042_CR10","doi-asserted-by":"publisher","first-page":"290","DOI":"10.1093\/brain\/awh729","volume":"129","author":"JD Schmahmann","year":"2006","unstructured":"Schmahmann JD, Caplan D (2006) Cognition, emotion and the cerebellum. Brain: J Neurol 129:290\u2013292","journal-title":"Brain: J Neurol"},{"key":"12042_CR11","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1016\/j.jns.2014.10.008","volume":"347","author":"A Ruet","year":"2014","unstructured":"Ruet A, Hamel D, Deloire MS, Charre-Morin J, Saubusse A, Brochet B (2014) Information processing speed impairment and cerebellar dysfunction in relapsing-remitting multiple sclerosis. J Neurol Sci 347:246\u2013250","journal-title":"J Neurol Sci"},{"key":"12042_CR12","doi-asserted-by":"publisher","first-page":"3141","DOI":"10.1002\/hbm.23580","volume":"38","author":"H Tabatabaei-Jafari","year":"2017","unstructured":"Tabatabaei-Jafari H, Walsh E, Shaw ME, Cherbuin N, Alzheimer\u2019s Disease Neuroimaging I (2017) The cerebellum shrinks faster than normal ageing in Alzheimer\u2019s disease but not in mild cognitive impairment. Hum Brain Mapp 38:3141\u20133150","journal-title":"Hum Brain Mapp"},{"key":"12042_CR13","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1038\/s41572-019-0074-3","volume":"5","author":"T Klockgether","year":"2019","unstructured":"Klockgether T, Mariotti C, Paulson HL (2019) Spinocerebellar ataxia. Nat Rev Dis Primers 5:24","journal-title":"Nat Rev Dis Primers"},{"key":"12042_CR14","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1002\/ana.410390411","volume":"39","author":"A D\u00fcrr","year":"1996","unstructured":"D\u00fcrr A, Stevanin G, Cancel G, Duyckaerts C, Abbas N, Didierjean O, Chneiweiss H, Benomar A, Lyon-Caen O, Julien J, Serdaru M, Penet C, Agid Y, Brice A (1996) Spinocerebellar ataxia 3 and Machado-Joseph disease: clinical, molecular, and neuropathological features. Ann Neurol 39:490\u2013499","journal-title":"Ann Neurol"},{"key":"12042_CR15","doi-asserted-by":"publisher","first-page":"1125","DOI":"10.1002\/mds.25451","volume":"28","author":"RP Guimaraes","year":"2013","unstructured":"Guimaraes RP, D\u2019Abreu A, Yasuda CL, Franca MC Jr, Silva BH, Cappabianco FA, Bergo FP, Lopes-Cendes IT, Cendes F (2013) A multimodal evaluation of microstructural white matter damage in spinocerebellar ataxia type 3. Mov Disord 28:1125\u20131132","journal-title":"Mov Disord"},{"issue":"277\u2013283","key":"12042_CR16","first-page":"e223","volume":"22","author":"TJ de Rezende","year":"2015","unstructured":"de Rezende TJ, D\u2019Abreu A, Guimaraes RP, Lopes TM, Lopes-Cendes I, Cendes F, Castellano G, Franca MC Jr (2015) Cerebral cortex involvement in Machado-Joseph disease. Eur J Neurol 22(277\u2013283):e223-274","journal-title":"Eur J Neurol"},{"key":"12042_CR17","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1002\/ana.25297","volume":"84","author":"TJR Rezende","year":"2018","unstructured":"Rezende TJR, de Paiva JLR, Martinez ARM, Lopes-Cendes I, Pedroso JL, Barsottini OGP, Cendes F, Franca MC Jr (2018) Structural signature of SCA3: from presymptomatic to late disease stages. Ann Neurol 84:401\u2013408","journal-title":"Ann Neurol"},{"key":"12042_CR18","doi-asserted-by":"publisher","first-page":"944","DOI":"10.1007\/s00415-022-11441-z","volume":"270","author":"H Hengel","year":"2023","unstructured":"Hengel H, Martus P, Faber J, Giunit P, Garcia-Moreno H, Solanky N, Klockgether T, Reetz K, van de Warrenburg BP, Santana MM, Silva P, Cunha I, de Almeida LP, Timmann D, Infante J, de Vries J, Lima M, Pires P, Bushara K, Jacobi H, Onyike C, Schmahmann JD, H\u00fcbener-Schmid J, Synofzik M, Sch\u00f6ls L (2023) The frequency of non-motor symptoms in SCA3 and their association with disease severity and lifestyle factors. J Neurol 270:944\u2013952","journal-title":"J Neurol"},{"key":"12042_CR19","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1007\/s12311-021-01282-3","volume":"21","author":"KH Yap","year":"2022","unstructured":"Yap KH, Kessels RPC, Azmin S, van de Warrenburg B, Mohamed Ibrahim N (2022) Neurocognitive changes in spinocerebellar Ataxia type 3: a systematic review with a Narrative design. Cerebellum 21:314\u2013327","journal-title":"Cerebellum"},{"key":"12042_CR20","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1016\/j.tins.2008.02.011","volume":"31","author":"H Ackermann","year":"2008","unstructured":"Ackermann H (2008) Cerebellar contributions to speech production and speech perception: psycholinguistic and neurobiological perspectives. Trends Neurosci 31:265\u2013272","journal-title":"Trends Neurosci"},{"key":"12042_CR21","doi-asserted-by":"publisher","first-page":"2370","DOI":"10.1007\/s00415-013-6998-8","volume":"260","author":"TM Lopes","year":"2013","unstructured":"Lopes TM, D\u2019Abreu A, Fran\u00e7a MC Jr, Yasuda CL, Betting LE, Samara AB, Castellano G, Somazz JC, Balthazar ML, Lopes-Cendes I, Cendes F (2013) Widespread neuronal damage and cognitive dysfunction in spinocerebellar ataxia type 3. J Neurol 260:2370\u20132379","journal-title":"J Neurol"},{"key":"12042_CR22","doi-asserted-by":"publisher","first-page":"1777","DOI":"10.1007\/s00415-015-7807-3","volume":"262","author":"UC Silva","year":"2015","unstructured":"Silva UC, Marques W Jr, Lourenco CM, Hallak JE, Osorio FL (2015) Psychiatric disorders, spinocerebellar ataxia type 3 and CAG expansion. J Neurol 262:1777\u20131779","journal-title":"J Neurol"},{"key":"12042_CR23","doi-asserted-by":"publisher","first-page":"1182","DOI":"10.1093\/brain\/awv064","volume":"138","author":"MR Stefanescu","year":"2015","unstructured":"Stefanescu MR, Dohnalek M, Maderwald S, Th\u00fcrling M, Minnerop M, Beck A, Schlamann M, Diedrichsen J, Ladd ME, Timmann D (2015) Structural and functional MRI abnormalities of cerebellar cortex and nuclei in SCA3, SCA6 and Friedreich\u2019s ataxia. Brain: J Neurol 138:1182\u20131197","journal-title":"Brain: J Neurol"},{"key":"12042_CR24","doi-asserted-by":"publisher","first-page":"916","DOI":"10.1016\/j.neuroimage.2016.11.003","volume":"147","author":"JE Romero","year":"2017","unstructured":"Romero JE, Coupe P, Giraud R, Ta VT, Fonov V, Park MTM, Chakravarty MM, Voineskos AN, Manjon JV (2017) CERES: a new cerebellum lobule segmentation method. Neuroimage 147:916\u2013924","journal-title":"Neuroimage"},{"key":"12042_CR25","doi-asserted-by":"publisher","first-page":"1619","DOI":"10.1016\/S0140-6736(17)30548-2","volume":"389","author":"Y Zeng","year":"2017","unstructured":"Zeng Y, Feng Q, Hesketh T, Christensen K, Vaupel JW (2017) Survival, disabilities in activities of daily living, and physical and cognitive functioning among the oldest-old in China: a cohort study. Lancet 389:1619\u20131629","journal-title":"Lancet"},{"key":"12042_CR26","doi-asserted-by":"publisher","first-page":"1497","DOI":"10.1016\/j.jocn.2011.11.039","volume":"19","author":"K Nie","year":"2012","unstructured":"Nie K, Zhang Y, Wang L, Zhao J, Huang Z, Gan R, Li S, Wang L (2012) A pilot study of psychometric properties of the Beijing version of montreal cognitive assessment in patients with idiopathic Parkinson\u2019s disease in China. J Clin Neurosci 19:1497\u20131500","journal-title":"J Clin Neurosci"},{"key":"12042_CR27","doi-asserted-by":"publisher","first-page":"1839","DOI":"10.1177\/1352458515576982","volume":"21","author":"N Zhang","year":"2015","unstructured":"Zhang N, Li YJ, Fu Y, Shao JH, Luo LL, Yang L, Shi FD, Liu Y (2015) Cognitive impairment in Chinese neuromyelitis optica. Mult Scler 21:1839\u20131846","journal-title":"Mult Scler"},{"key":"12042_CR28","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2022.103838","volume":"65","author":"X Dong","year":"2022","unstructured":"Dong X, Xu G, Wang J, Yin N, Meng N (2022) Clinical and MRI predictors of cognitive decline in patients with relapsing-remitting multiple sclerosis: a 2-year longitudinal study. Mult Scler Relat Disord 65:103838","journal-title":"Mult Scler Relat Disord"},{"issue":"Suppl 2","key":"12042_CR29","first-page":"II22","volume":"254","author":"RH Benedict","year":"2007","unstructured":"Benedict RH, Zivadinov R (2007) Reliability and validity of neuropsychological screening and assessment strategies in MS. J Neurol 254(Suppl 2):II22\u2013II25","journal-title":"J Neurol"},{"key":"12042_CR30","doi-asserted-by":"publisher","first-page":"3456","DOI":"10.1007\/s00415-021-10516-7","volume":"268","author":"R Maas","year":"2021","unstructured":"Maas R, Killaars S, van de Warrenburg BPC, Schutter D (2021) The cerebellar cognitive affective syndrome scale reveals early neuropsychological deficits in SCA3 patients. J Neurol 268:3456\u20133466","journal-title":"J Neurol"},{"key":"12042_CR31","doi-asserted-by":"publisher","first-page":"4363","DOI":"10.1007\/s00415-022-11071-5","volume":"269","author":"A Thieme","year":"2022","unstructured":"Thieme A, Faber J, Sulzer P, Reetz K, Dogan I, Barkhoff M, Krahe J, Jacobi H, Aktories JE, Minnerop M, Elben S, van der Veen R, M\u00fcller J, Batsikadze G, Konczak J, Synofzik M, Roeske S, Timmann D (2022) The CCAS-scale in hereditary ataxias: helpful on the group level, particularly in SCA3, but limited in individual patients. J Neurol 269:4363\u20134374","journal-title":"J Neurol"},{"key":"12042_CR32","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1192\/bjp.152.5.660","volume":"152","author":"YP Zheng","year":"1988","unstructured":"Zheng YP, Zhao JP, Phillips M, Liu JB, Cai MF, Sun SQ, Huang MF (1988) Validity and reliability of the Chinese Hamilton depression rating scale. Br J Psychiatry 152:660\u2013664","journal-title":"Br J Psychiatry"},{"key":"12042_CR33","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1111\/j.2044-8341.1959.tb00467.x","volume":"32","author":"M Hamilton","year":"1959","unstructured":"Hamilton M (1959) The assessment of anxiety states by rating. Br J Med Psychol 32:50\u201355","journal-title":"Br J Med Psychol"},{"key":"12042_CR34","doi-asserted-by":"publisher","first-page":"1186","DOI":"10.1080\/13854046.2012.725101","volume":"26","author":"JB Dusankova","year":"2012","unstructured":"Dusankova JB, Kalincik T, Havrdova E, Benedict RH (2012) Cross cultural validation of the minimal assessment of cognitive function in multiple sclerosis (MACFIMS) and the brief international cognitive assessment for multiple sclerosis (BICAMS). Clin Neuropsychol 26:1186\u20131200","journal-title":"Clin Neuropsychol"},{"key":"12042_CR35","doi-asserted-by":"publisher","first-page":"1717","DOI":"10.1212\/01.wnl.0000219042.60538.92","volume":"66","author":"T Schmitz-Hubsch","year":"2006","unstructured":"Schmitz-Hubsch T, du Montcel ST, Baliko L, Berciano J, Boesch S, Depondt C, Giunti P, Globas C, Infante J, Kang JS, Kremer B, Mariotti C, Melegh B, Pandolfo M, Rakowicz M, Ribai P, Rola R, Schols L, Szymanski S, van de Warrenburg BP, Durr A, Klockgether T, Fancellu R (2006) Scale for the assessment and rating of ataxia: development of a new clinical scale. Neurology 66:1717\u20131720","journal-title":"Neurology"},{"key":"12042_CR36","doi-asserted-by":"publisher","first-page":"205","DOI":"10.1016\/S0022-510X(96)00231-6","volume":"145","author":"P Trouillas","year":"1997","unstructured":"Trouillas P, Takayanagi T, Hallett M, Currier R, Subramony S, Wessel K, Bryer A, Diener H, Massaquoi S, Gomez C, Coutinho P, Ben Hamida M, Campanella G, Filla A, Schut L, Timann D, Honnorat J, Nighoghossian N, Manyam B (1997) International cooperative Ataxia rating scale for pharmacological assessment of the cerebellar syndrome. The Ataxia neuropharmacology committee of the world federation of neurology. J Neurol Sci 145:205\u2013211","journal-title":"J Neurol Sci"},{"key":"12042_CR37","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1212\/WNL.0000000000001711","volume":"85","author":"RP Maas","year":"2015","unstructured":"Maas RP, van Gaalen J, Klockgether T, van de Warrenburg BP (2015) The preclinical stage of spinocerebellar ataxias. Neurology 85:96\u2013103","journal-title":"Neurology"},{"key":"12042_CR38","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1159\/000357404","volume":"71","author":"L Feng","year":"2014","unstructured":"Feng L, Chen DB, Hou L, Huang LH, Lu SY, Liang XL, Li XH (2014) Cognitive impairment in native Chinese with spinocerebellar ataxia type 3. Eur Neurol 71:262\u2013270","journal-title":"Eur Neurol"},{"key":"12042_CR39","doi-asserted-by":"publisher","first-page":"391","DOI":"10.1186\/s13023-021-02014-w","volume":"16","author":"Q Lin","year":"2021","unstructured":"Lin Q, Liu Y, Ye Z, Hu J, Cai W, Weng Q, Chen W, Wang N, Cao D, Lin Y, Fu Y (2021) Potential markers for sample size estimations in hereditary spastic paraplegia type 5. Orphanet J Rare Dis 16:391","journal-title":"Orphanet J Rare Dis"},{"key":"12042_CR40","doi-asserted-by":"publisher","first-page":"2989","DOI":"10.1007\/s00415-021-10890-2","volume":"269","author":"M Li","year":"2021","unstructured":"Li M, Chen X, Xu H, Huang Z, Chen N, Tu Y, Gan S, Hu J (2021) Brain structural abnormalities in the preclinical stage of Machado-Joseph disease\/spinocerebellar ataxia type 3 (MJD\/SCA3): evaluation by MRI morphometry, diffusion tensor imaging and neurite orientation dispersion and density imaging. J Neurol 269:2989\u20132998","journal-title":"J Neurol"},{"key":"12042_CR41","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1007\/s12311-011-0318-6","volume":"11","author":"P Braga-Neto","year":"2012","unstructured":"Braga-Neto P, Pedroso JL, Alessi H, Dutra LA, Felicio AC, Minett T, Weisman P, Santos-Galduroz RF, Bertolucci PH, Gabbai AA, Barsottini OG (2012) Cerebellar cognitive affective syndrome in Machado Joseph disease: core clinical features. Cerebellum 11:549\u2013556","journal-title":"Cerebellum"},{"key":"12042_CR42","first-page":"5765","volume":"7","author":"J Ma","year":"2014","unstructured":"Ma J, Wu C, Lei J, Zhang X (2014) Cognitive impairments in patients with spinocerebellar ataxia types 1, 2 and 3 are positively correlated to the clinical severity of ataxia symptoms. Int J Clin Exp Med 7:5765\u20135771","journal-title":"Int J Clin Exp Med"},{"key":"12042_CR43","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1093\/brain\/awx317","volume":"141","author":"F Hoche","year":"2018","unstructured":"Hoche F, Guell X, Vangel MG, Sherman JC, Schmahmann JD (2018) The cerebellar cognitive affective\/Schmahmann syndrome scale. Brain 141:248\u2013270","journal-title":"Brain"},{"key":"12042_CR44","doi-asserted-by":"publisher","first-page":"489","DOI":"10.1016\/j.neuroimage.2008.08.039","volume":"44","author":"CJ Stoodley","year":"2009","unstructured":"Stoodley CJ, Schmahmann JD (2009) Functional topography in the human cerebellum: a meta-analysis of neuroimaging studies. Neuroimage 44:489\u2013501","journal-title":"Neuroimage"},{"key":"12042_CR45","doi-asserted-by":"publisher","first-page":"2483","DOI":"10.1097\/00001756-200108080-00039","volume":"12","author":"KO Bushara","year":"2001","unstructured":"Bushara KO, Wheat JM, Khan A, Mock BJ, Turski PA, Sorenson J, Brooks BR (2001) Multiple tactile maps in the human cerebellum. NeuroReport 12:2483\u20132486","journal-title":"NeuroReport"},{"key":"12042_CR46","doi-asserted-by":"publisher","first-page":"1183","DOI":"10.3389\/fneur.2019.01183","volume":"10","author":"K Bando","year":"2019","unstructured":"Bando K, Honda T, Ishikawa K, Takahashi Y, Mizusawa H, Hanakawa T (2019) Impaired adaptive motor learning is correlated with cerebellar hemispheric gray matter atrophy in spinocerebellar ataxia patients: a voxel-based morphometry study. Front Neurol 10:1183","journal-title":"Front Neurol"},{"key":"12042_CR47","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1007\/s00415-018-8738-6","volume":"265","author":"G Olivito","year":"2018","unstructured":"Olivito G, Lupo M, Iacobacci C, Clausi S, Romano S, Masciullo M, Molinari M, Cercignani M, Bozzali M, Leggio M (2018) Structural cerebellar correlates of cognitive functions in spinocerebellar ataxia type 2. J Neurol 265:597\u2013606","journal-title":"J Neurol"},{"key":"12042_CR48","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1007\/s00429-011-0310-4","volume":"216","author":"F D'Agata","year":"2011","unstructured":"D\u2019Agata F, Caroppo P, Boghi A, Coriasco M, Caglio M, Baudino B, Sacco K, Cauda F, Geda E, Bergui M, Geminiani G, Bradac GB, Orsi L, Mortara P (2011) Linking coordinative and executive dysfunctions to atrophy in spinocerebellar ataxia 2 patients. Brain Struct Funct 216:275\u2013288","journal-title":"Brain Struct Funct"},{"key":"12042_CR49","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1002\/acn3.315","volume":"3","author":"I Dogan","year":"2016","unstructured":"Dogan I, Tinnemann E, Romanzetti S, Mirzazade S, Costa AS, Werner CJ, Heim S, Fedosov K, Schulz S, Timmann D, Giordano IA, Klockgether T, Schulz JB, Reetz K (2016) Cognition in Friedreich\u2019s ataxia: a behavioral and multimodal imaging study. Ann Clin Transl Neurol 3:572\u2013587","journal-title":"Ann Clin Transl Neurol"},{"key":"12042_CR50","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2019.101891","volume":"23","author":"H Yang","year":"2019","unstructured":"Yang H, Wang N, Luo X, Lv H, Liu H, Li Y, Fan G (2019) Cerebellar atrophy and its contribution to motor and cognitive performance in multiple system atrophy. Neuroimage Clin 23:101891","journal-title":"Neuroimage Clin"},{"key":"12042_CR51","doi-asserted-by":"publisher","first-page":"430","DOI":"10.3389\/fncel.2018.00430","volume":"12","author":"S Toniolo","year":"2018","unstructured":"Toniolo S, Serra L, Olivito G, Marra C, Bozzali M, Cercignani M (2018) Patterns of cerebellar gray matter atrophy across Alzheimer\u2019s disease progression. Front Cell Neurosci 12:430","journal-title":"Front Cell Neurosci"},{"key":"12042_CR52","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1136\/jnnp-2016-313867","volume":"88","author":"A Moroso","year":"2017","unstructured":"Moroso A, Ruet A, Lamargue-Hamel D, Munsch F, Deloire M, Coup\u00e9 P, Ouallet JC, Planche V, Moscufo N, Meier DS, Tourdias T, Guttmann CR, Dousset V, Brochet B (2017) Posterior lobules of the cerebellum and information processing speed at various stages of multiple sclerosis. J Neurol Neurosurg Psychiatry 88:146\u2013151","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"12042_CR53","doi-asserted-by":"publisher","first-page":"1592","DOI":"10.1016\/j.apmr.2021.12.010","volume":"103","author":"NE Fritz","year":"2022","unstructured":"Fritz NE, Edwards EM, Ye C, Prince J, Yang Z, Gressett T, Keller J, Myers E, Calabresi PA, Zackowski KM (2022) Cerebellar contributions to motor and cognitive control in multiple sclerosis(\u2730\u2730\u2730). Arch Phys Med Rehabil 103:1592\u20131599","journal-title":"Arch Phys Med Rehabil"},{"key":"12042_CR54","doi-asserted-by":"publisher","first-page":"924","DOI":"10.1016\/j.neurol.2022.05.002","volume":"178","author":"N Morelli","year":"2022","unstructured":"Morelli N (2022) Patients with Parkinson\u2019s disease and a history of falls have decreased cerebellar grey matter volumes in the cognitive cerebellum. Rev Neurol (Paris) 178:924\u2013931","journal-title":"Rev Neurol (Paris)"},{"key":"12042_CR55","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/j.cortex.2021.12.014","volume":"149","author":"Y Chen","year":"2022","unstructured":"Chen Y, Landin-Romero R, Kumfor F, Irish M, Dobson-Stone C, Kwok JB, Halliday GM, Hodges JR, Piguet O (2022) Cerebellar integrity and contributions to cognition in C9orf72-mediated frontotemporal dementia. Cortex 149:73\u201384","journal-title":"Cortex"},{"key":"12042_CR56","doi-asserted-by":"publisher","first-page":"2310","DOI":"10.1093\/brain\/awab157","volume":"144","author":"A Benussi","year":"2021","unstructured":"Benussi A, Cantoni V, Manes M, Libri I, Dell\u2019Era V, Datta A, Thomas C, Ferrari C, Di Fonzo A, Fancellu R, Grassi M, Brusco A, Alberici A, Borroni B (2021) Motor and cognitive outcomes of cerebello-spinal stimulation in neurodegenerative ataxia. Brain 144:2310\u20132321","journal-title":"Brain"},{"key":"12042_CR57","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2022.827993","volume":"14","author":"XY Chen","year":"2022","unstructured":"Chen XY, Lian YH, Liu XH, Sikandar A, Li MC, Xu HL, Hu JP, Chen QL, Gan SR (2022) Effects of repetitive transcranial magnetic stimulation on cerebellar metabolism in patients with spinocerebellar ataxia type 3. Front Aging Neurosci 14:827993","journal-title":"Front Aging Neurosci"},{"key":"12042_CR58","doi-asserted-by":"publisher","first-page":"1259","DOI":"10.1007\/s13311-022-01231-w","volume":"19","author":"R Maas","year":"2022","unstructured":"Maas R, Teerenstra S, Toni I, Klockgether T, Schutter D, van de Warrenburg BPC (2022) Cerebellar transcranial direct current stimulation in spinocerebellar ataxia type 3: a randomized, double-blind, sham-controlled trial. Neurotherapeutics 19:1259\u20131272","journal-title":"Neurotherapeutics"},{"key":"12042_CR59","doi-asserted-by":"publisher","first-page":"1604","DOI":"10.1523\/JNEUROSCI.2818-16.2017","volume":"37","author":"AM D'Mello","year":"2017","unstructured":"D\u2019Mello AM, Turkeltaub PE, Stoodley CJ (2017) Cerebellar tDCS modulates neural circuits during semantic prediction: a combined tDCS-fMRI study. J Neurosci 37:1604\u20131613","journal-title":"J Neurosci"},{"key":"12042_CR60","doi-asserted-by":"publisher","first-page":"152","DOI":"10.1016\/j.clinph.2023.06.019","volume":"153","author":"R Maas","year":"2023","unstructured":"Maas R, Faber J, van de Warrenburg BPC, Schutter D (2023) Interindividual differences in posterior fossa morphometry affect cerebellar tDCS-induced electric field strength. Clin Neurophysiol 153:152\u2013165","journal-title":"Clin Neurophysiol"},{"key":"12042_CR61","doi-asserted-by":"publisher","first-page":"1722","DOI":"10.1523\/JNEUROSCI.1532-19.2019","volume":"40","author":"B Yacoubi","year":"2020","unstructured":"Yacoubi B, Casamento-Moran A, Burciu RG, Subramony SH, Vaillancourt DE, Christou EA (2020) Temporal invariance in SCA6 is related to smaller cerebellar lobule VI and greater disease severity. J Neurosci 40:1722\u20131731","journal-title":"J Neurosci"},{"key":"12042_CR62","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1136\/jnnp.2007.119883","volume":"79","author":"M Suenaga","year":"2008","unstructured":"Suenaga M, Kawai Y, Watanabe H, Atsuta N, Ito M, Tanaka F, Katsuno M, Fukatsu H, Naganawa S, Sobue G (2008) Cognitive impairment in spinocerebellar ataxia type 6. J Neurol Neurosurg Psychiatry 79:496\u2013499","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"12042_CR63","doi-asserted-by":"publisher","first-page":"491","DOI":"10.1038\/nrn3256","volume":"13","author":"C Grady","year":"2012","unstructured":"Grady C (2012) The cognitive neuroscience of ageing. Nat Rev Neurosci 13:491\u2013505","journal-title":"Nat Rev Neurosci"},{"key":"12042_CR64","doi-asserted-by":"publisher","first-page":"246","DOI":"10.1186\/s12967-023-04090-x","volume":"21","author":"M Kumar","year":"2023","unstructured":"Kumar M, Hiremath C, Khokhar SK, Bansal E, Sagar KJV, Padmanabha H, Girimaji AS, Narayan S, Kishore MT, Yamini BK, JacFredo AR, Saini J, Bharath RD (2023) Altered cerebellar lobular volumes correlate with clinical deficits in siblings and children with ASD: evidence from toddlers. J Transl Med 21:246","journal-title":"J Transl Med"},{"key":"12042_CR65","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/13803395.2023.2241653","volume":"28","author":"K Torres","year":"2023","unstructured":"Torres K (2023) Comparison of core and process scores on the California verbal learning test-3 for Parkinson\u2019s disease and essential tremor patients. J Clin Exp Neuropsychol 28:1\u201315","journal-title":"J Clin Exp Neuropsychol"},{"key":"12042_CR66","doi-asserted-by":"publisher","first-page":"403","DOI":"10.1002\/hbm.26058","volume":"44","author":"Y Li","year":"2023","unstructured":"Li Y, Liu H, Yu H, Yang H, Guo M, Cao C, Pang H, Liu Y, Cao K, Fan G (2023) Alterations of voxel-wise spontaneous activity and corresponding brain functional networks in multiple system atrophy patients with mild cognitive impairment. Hum Brain Mapp 44:403\u2013417","journal-title":"Hum Brain Mapp"},{"key":"12042_CR67","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1002\/ana.20742","volume":"59","author":"O Monchi","year":"2006","unstructured":"Monchi O, Petrides M, Strafella AP, Worsley KJ, Doyon J (2006) Functional role of the basal ganglia in the planning and execution of actions. Ann Neurol 59:257\u2013264","journal-title":"Ann Neurol"},{"key":"12042_CR68","doi-asserted-by":"publisher","first-page":"917","DOI":"10.1002\/mds.26956","volume":"32","author":"L Anderkova","year":"2017","unstructured":"Anderkova L, Barton M, Rektorova I (2017) Striato-cortical connections in Parkinson\u2019s and Alzheimer\u2019s diseases: relation to cognition. Mov Disord 32:917\u2013922","journal-title":"Mov Disord"}],"container-title":["Journal of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00415-023-12042-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00415-023-12042-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00415-023-12042-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,31]],"date-time":"2024-01-31T03:03:17Z","timestamp":1706670197000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00415-023-12042-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,18]]},"references-count":68,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,2]]}},"alternative-id":["12042"],"URL":"https:\/\/doi.org\/10.1007\/s00415-023-12042-0","relation":{},"ISSN":["0340-5354","1432-1459"],"issn-type":[{"value":"0340-5354","type":"print"},{"value":"1432-1459","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,18]]},"assertion":[{"value":"13 July 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 September 2023","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 October 2023","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 October 2023","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and\/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}