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Cecchetti has received speaker honoraria from Neopharmed Gentili. F. Agosta is Associate Editor of <i>NeuroImage: Clinical<\/i>, has received speaker honoraria from Biogen Idec, Italfarmaco, Roche, Zambon and Eli Lilly, and receives or has received research supports from the Italian Ministry of Health, the Italian Ministry of University and Research, AriSLA (Fondazione Italiana di Ricerca per la SLA), the European Research Council, the EU Joint Programme \u2013 Neurodegenerative Disease Research (JPND), and Foundation Research on Alzheimer Disease (France). G. Rugarli has nothing to disclose. E.G. Spinelli has nothing to disclose. A.Ghirelli has nothing to disclose. M. Zavarella has nothing to disclose. I. Bottale has nothing to disclose. F. Orlandi has nothing to disclose. R. Santangelo has nothing to disclose. F. Caso has nothing to disclose. G. Magnani has nothing to disclose. M. Filippi is Editor-in-Chief of the <i>Journal of Neurology<\/i>, Associate Editor of <i>Human Brain Mapping<\/i>, <i>Neurological Sciences,<\/i> and <i>Radiology<\/i>; received compensation for consulting services from Alexion, Almirall, Biogen, Merck, Novartis, Roche, Sanofi; speaking activities from Bayer, Biogen, Celgene, Chiesi Italia SpA, Eli Lilly, Genzyme, Janssen, Merck-Serono, Neopharmed Gentili, Novartis, Novo Nordisk, Roche, Sanofi, Takeda, and TEVA; participation in Advisory Boards for Alexion, Biogen, Bristol-Myers Squibb, Merck, Novartis, Roche, Sanofi, Sanofi-Aventis, Sanofi-Genzyme, Takeda; scientific direction of educational events for Biogen, Merck, Roche, Celgene, Bristol-Myers Squibb, Lilly, Novartis, Sanofi-Genzyme; he receives research support from Biogen Idec, Merck-Serono, Novartis, Roche, the Italian Ministry of Health, the Italian Ministry of University and Research, and Fondazione Italiana Sclerosi Multipla.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The ethical standards committee on human experimentation of IRCCS San Raffaele Scientific Institute (Milan, Italy) approved the study protocol and all participants provided written informed consent prior to study inclusion. The study was performed in accordance with the ethical standards as laid down in the 1964 Declaration of Helsinki and its later amendments.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent statement"}}]}}