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Boaventura has received a speaker honorarium and\/or travel expenses for scientific meetings from Biogen, Horizon, Amgen, AstraZeneca, Merck, Novartis and Roche and received a grant as ECTRIMS- Clinical Training fellow; D.C. Fragoso reports no disclosures relevant to the manuscript; I. Avolio reports no disclosures relevant to the manuscript; S.L.A. Pereira has received a speaker honorarium and\/or travel expenses for scientific meetings from Biogen, Horizon\/Amgen, Alexion, Merck, Novartis and Roche; D. Callegaro has received a speaker honorarium and\/or travel expenses for scientific meetings from Biogen, Horizon, Merck, Novartis and Roche; D.K. Sato reports grants from Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico (CNPq)\u2014Brazil, grants from Funda\u00e7\u00e3o e Amparo \u00e0 Pesquisa do Estado do Rio Grande do Sul (FAPERGS)\u2014Brazil, Research grants from Teva, Merck, Biogen for investigator-initiated studies and consulting fees from Merck, Roche, Horizon and Alexion.; C.C. Leite reports no disclosures relevant to the manuscript; A. Rovira serves\/served on scientific advisory boards for Novartis, Sanofi- Genzyme, Icometrix, Synthetic MR, Bayer, Biogen and OLEA Medical, and has received speaker honoraria from Bayer, Sanofi-Genzyme, Bracco, Merck-Serono, Teva Pharmaceutical Industries Ltd, Novartis, Roche and Biogen; J.S.-Garriga has engaged in consulting and\/or participating as speaker\/chair in events organized by Merck, Bayer, Celgene, Sanofi and Biogen, is director of Revista de Neurolog\u00eda and editor for controversies of the Multiple Sclerosis Journal; D. Pareto holds a research grant from Instituto Carlos III (PI22\/01709) cofunded by the European Union; C.M. Rimkus has received a grant from MSIF-ECTRIMS, speaker honoraria from Roche, Guerbet, Biogen and is associate editor of Arquivos de Neuropsiquiatria.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}],"article-number":"157"}}