{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T21:33:31Z","timestamp":1789680811172,"version":"4.0.1"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T00:00:00Z","timestamp":1741824000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T00:00:00Z","timestamp":1741824000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Neurol"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>Choosing a device-assisted treatment for persons with Parkinson\u2019s disease (PwPD) is a complex decision. We developed a shared decision-making (SDM) intervention to facilitate this decision. In this study, we evaluate the feasibility of this intervention from the patients\u2019 perspective.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>We performed a multi-center, mixed-methods feasibility study with an uncontrolled pre-post-intervention design. Five neurologists and seven Parkinson nurse specialists from five Dutch hospitals participated. We aimed to enroll 20 PwPD in the usual-care group receiving decision support as usual, and 20 PwPD receiving the SDM intervention. The intervention consisted of a patient decision aid and a training for professionals. We evaluated feasibility by measuring acceptability, level of implementation, efficacy and the study procedures. For data collection, we used questionnaires, interviews, cognitive testing, consultation recordings, fieldnotes, and usage of the patient decision aid.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>We included 19 PwPD in the usual-care group and 13 in the intervention group. Acceptability was good and implementation levels at the patient level were adequate: 92% of the participants used the patient decision aid, of which 77% the website and 69% the value clarification tool. The intervention improved PwPD\u2019s knowledge on treatment options, however, it did not improve SDM. The SDM intervention was not used as intended and the initial treatment preference of either the PwPD or the professional directed the information exchange.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>Inclusion of PwPD for the study was limited. Acceptability of the SDM intervention was good, however, the patient decision aid should be used in collaboration between physicians and patients to enhance SDM.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Trial registration<\/jats:title>\n            <jats:p>NTR6649, registered 28\u201308\u20132017 (available through ICTRP search portal).<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s00415-025-12972-x","type":"journal-article","created":{"date-parts":[[2025,3,13]],"date-time":"2025-03-13T12:02:23Z","timestamp":1741867343000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["A decision aid is not the quick fix for improving shared decision-making in advanced Parkinson\u2019s disease: results of a mixed methods feasibility study"],"prefix":"10.1007","volume":"272","clinical-trial-number":[{"clinical-trial-number":"ntr6649","registry":"10.18810\/dutch-trial-register"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1751-8650","authenticated-orcid":false,"given":"Frouke A. 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Bloem, MD, PhD, FRCPE, FEAN: Prof. Bloem serves as the co-Editor in Chief for the Journal of Parkinson\u2019s disease, serves on the editorial board of Practical Neurology and Digital Biomarkers, has received fees from serving on the scientific advisory board for the Critical Path Institute, Gyenno Science, MedRhythms, UCB, Kyowa Kirin and Zambon (paid to the Institute), has received fees for speaking at conferences from AbbVie, Bial, Biogen, GE Healthcare, Oruen, Roche, UCB and Zambon (paid to the Institute), and has received research support from Biogen, Cure Parkinson\u2019s, Davis Phinney Foundation, Edmond J. Safra Foundation, Fred Foundation, Gatsby Foundation, Hersenstichting Nederland, Horizon 2020, IRLAB Therapeutics, Maag Lever Darm Stichting, Michael J Fox Foundation, Ministry of Agriculture, Ministry of Economic Affairs & Climate Policy, Ministry of Health, Welfare and Sport, Netherlands Organization for Scientific Research (ZonMw), Not Impossible, Parkinson Vereniging, Parkinson\u2019s Foundation, Parkinson\u2019s UK, Stichting Alkemade-Keuls, Stichting Parkinson NL, Stichting Woelse Waard, Topsector Life Sciences and Health, UCB, Verily Life Sciences, Roche and Zambon. Prof. Bloem does not hold any stocks or stock options with any companies that are connected to Parkinson\u2019s disease or to any of his clinical or research activities. Grants\/research support (paid to the Institute) \u00b7 Biogen \u00b7 Cure Parkinson\u2019s \u00b7 Davis Phinney Foundation \u00b7 Edmond J. Safra Foundation \u00b7 Fred Foundation \u00b7 Gatsby Foundation \u00b7 Hersenstichting Nederland \u00b7 Horizon 2020 \u00b7 IRLAB Therapeutics \u00b7 Maag Lever Darm Stichting \u00b7 Michael J Fox Foundation \u00b7 Ministry of Agriculture \u00b7 Ministry of Economic Affairs & Climate Policy \u00b7 Ministry of Health, Welfare and Sport \u00b7 Netherlands Organization for Scientific Research (ZonMw) \u00b7 Not Impossible \u00b7 Parkinson Vereniging \u00b7 Parkinson\u2019s Foundation \u00b7 Parkinson\u2019s UK \u00b7 Stichting Alkemade-Keuls \u00b7 Stichting Parkinson NL \u00b7 Stichting Woelse Waard \u00b7 Topsector Life Sciences and Health \u00b7 UCB \u00b7 Verily Life Sciences \u00b7 Roche \u00b7 Zambon. Consultant (paid to the Institute) \u00b7 Critical Path Institute \u00b7 Gyenno Science \u00b7 UCB \u00b7 Zambon SPEAKING (paid to the Institute) \u00b7 AbbVie \u00b7 Bial \u00b7 Biogen \u00b7 GE Healthcare \u00b7 Oruen \u00b7 Roche \u00b7 UCB \u00b7 Zambon STOCK SHAREHOLDER None. Memberships \u00b7 Officer of the Movement Disorder Society (currently Secretary) \u00b7 Member Executive Scientific Advisory Board (ESAB) of the Michael J Fox Foundation for Parkinson Research \u00b7 Co-Editor in Chief, Journal of Parkinson\u2019s Disease \u00b7 Member of the Editorial Board, Digital Biomarkers \u00b7 Member of the editorial board, Practical Neurology \u00b7 Member Critical Path Institute for Parkinson (). Other financial disclosures None. The other authors have no competing interests to declare that are relevant to the content of this article.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"The study was approved by the Medical Research Ethics Commission CMO Arnhem-Nijmegen in the Netherlands (registration number 2014\u20131489). All patients gave written informed consent prior to participating in this study and to audio-tape the consultations. The study has been registered in the Dutch Trial register, NTR6649 (available through ICTRP search portal).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and informed consent"}}],"article-number":"269"}}