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Dr. Feinstein has received grants from MS Society of Canada, CIHR, and Bristol Myers Squibb; royalties from Johns Hopkins University Press and Cambridge University Press; and honoraria from Novartis during the conduct of this study. All other authors have no relevant financial or non-financial interests to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"This retrospective chart review study involving human participants was performed in line with the principles of the Declaration of Helsinki. The study was approved by the Research Ethics Board at Sunnybrook Health Sciences Centre, affiliated to the University of Toronto (Date: December 30, 2021\/No. 5263).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Data were collected as part of a retrospective chart review and a waiver of consent was obtained as part of the research ethics board approval process.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}}],"article-number":"375"}}