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Eoin P. Flanagan has served on advisory boards for Alexion, Genentech, Horizon Therapeutics, and UCB. He has received research support from UCB. He received royalties from UpToDate. Dr Flanagan is a site principal investigator in a randomized clinical trial of rozanolixizumab for relapsing myelin oligodendrocyte glycoprotein antibody-associated disease run by UCB. Dr Flanagan is a site principal investigator and a member of the steering committee for a clinical trial of satralizumab for relapsing myelin oligodendrocyte glycoprotein antibody-associated disease run by Roche\/Genentech. Dr Flanagan is a Co-Investigator on a study of ravulizumab for neuromyelitis optica spectrum disorder run by Alexion. Dr Flanagan has given educational talks on neuromyelitis optica spectrum disorder funded by Alexion. Dr Flanagan has received funding from the NIH (R01 NS113828). Dr Flanagan has received honoraria for editing and writing articles for The Continuum Lifelong Learning in Neurology Journal which is a publication of the American Academy of Neurology. Dr Flanagan is a member of the medical advisory board of the MOG project and Sumaira Foundation. Dr Flanagan is an editorial board member of Neurology, Neuroimmunology and Neuroinflammation, The Journal of the Neurological Sciences, and Neuroimmunology Reports. A patent has been submitted on DACH1-IgG as a biomarker of paraneoplastic autoimmunity. Sean J. Pittock reports grants, personal fees, and non-financial support from Alexion Pharmaceuticals; grants, personal fees, and non-financial support from MedImmune\/Viela Bio; and personal fees for consulting from Genentech, Roche, UCB, and Astellas. He has two patents issued (8889102; application 12-678350; Neuromyelitis Optica Autoantibodies as a Marker for Neoplasia; and 9891219B2; application 12-573942; Methods for Treating Neuromyelitis Optica [NMO] by Administration of Eculizumab to an individual that is Aquaporin-4 [AQP4]-IgG Autoantibody positive) from which he has received royalties. Sean J. Pittock also has patents pending for IgGs to the following proteins as biomarkers of autoimmune neurological disorders: septin-5, kelch-like protein 11, GFAP, PDE10 A, and MAP1B. Ugur Uygunoglu has received honoraria for educational presentations internationally and at national meetings and symposia sponsored by F Hoffmann La-Roche, Merck-Serono, Novartis, Sanovel, Genveon, and Biogen Idec\/Gen Pharma of Turkiye, and consultation fees or travel and registration coverage for attending several national or international congresses or symposia from F Hoffmann La-Roche, Merck-Serono, ARIS, Sanovel, Genveon, and Biogen Idec\/Gen Pharma of Turkiye. Burcu Zeydan receives research funding from the NIH (U54 AG044170, K12 AR084222) and the MC Radiology Research, received consensus panel honorarium from Merck, and was the recipient of the Eugene and Marcia Applebaum Award.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"The study protocol was approved by the Mayo Clinic Institutional Review Boards.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from every participant.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}],"article-number":"434"}}