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Dr. Benedict has received a grant from Sanofi; and consulting fees from Roche, Sanofi, BMS, Clene, and Immunic Therapeutics. Dr. Oh has received grants from Biogen-Idec, Roche, and EMD-Serono; consulting fees from Biogen-Idec, EMD-Serono, BMS, Novartis, Eli-Lilly, Sanofi, and Roche; payment or honoraria from EMD-Serono, Biogen-Idec, Novartis, Roche, and Sanofi; participation on a Data Safety Monitoring or Advisory Board for Biogen-Idec, EMD-Serono, Roche, Novartis, and Sanofi; and leadership or fiduciary role as Chair of Medical Advisory Committee for MS Society of Canada during the conduct of this study. Dr. Feinstein has received grants from MS Canada, CIHR, and Bristol Myers Squibb; royalties from Johns Hopkins University Press and Cambridge University Press; and honoraria from Novartis, Roche and Merck.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of interest"}},{"value":"This retrospective chart review study involving human participants was performed in line with the principles of the Declaration of Helsinki. The study was approved by the Research Ethics Board at Sunnybrook Health Sciences Centre, affiliated with the University of Toronto (Date: December 30, 2021\/No. 5263).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Data were collected as part of a retrospective chart review and a waiver of consent was obtained as part of the research ethics board approval process.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}],"article-number":"190"}}