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Vukusic has received lecturing fees, travel grants and research support from Biogen, BMS-Celgene, Janssen, Merck, Novartis, Roche, Sanofi-Genzyme, Teva. C. Aguesse, E. Micoud, F. Venet, R. Pescarmona, G. Monneret, R. Marignier, P. Nicolas report no disclosure relevant to the subject of this manuscript.","order":1,"name":"Ethics","label":"Conflicts of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was conducted in compliance with the French National Data Protection Authority (CNIL) reference methodology MR004 (n\u00b024\u20135052) at Lyon University Hospital, in accordance with applicable French regulations on non-interventional research, which does not require formal ethics committee approval.","order":2,"name":"Ethics","label":"Ethical approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"MS patients were enrolled in the OFSEP registry and provided free and informed consent for the use of their data for non-interventional research purposes. All other patients were informed of the study and provided with the opportunity to object to the use of their data, in accordance with French regulations on non-interventional research.","order":3,"name":"Ethics","label":"Consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"469"}}