{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T08:29:17Z","timestamp":1786350557819,"version":"build-2736575974"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T00:00:00Z","timestamp":1784764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T00:00:00Z","timestamp":1784764800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J Neurol"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1007\/s00415-026-14012-8","type":"journal-article","created":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T15:04:13Z","timestamp":1784819053000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Effects of pulvinar and combined pulvinar\/anterior thalamic deep-brain stimulation\u00a0on sleep: preliminary results"],"prefix":"10.1007","volume":"273","author":[{"given":"Pietro","family":"Mattioli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asli Akyol","family":"Gurses","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Simula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romain","family":"Carron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrice","family":"Bartolomei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Lambert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6345-1288","authenticated-orcid":false,"given":"Francesca","family":"Pizzo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,23]]},"reference":[{"key":"14012_CR1","doi-asserted-by":"publisher","first-page":"805","DOI":"10.1212\/WNL.0000000000011839","volume":"96","author":"B Sultana","year":"2021","unstructured":"Sultana B, Panzini MA, Veilleux Carpentier A et al (2021) Incidence and prevalence of drug-resistant epilepsy: a systematic review and meta-analysis. Neurology 96:805\u2013817","journal-title":"Neurology"},{"key":"14012_CR2","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1016\/j.seizure.2019.10.020","volume":"73","author":"P Laboni","year":"2019","unstructured":"Laboni P, Hernandez L, Diana L, Tellez-zenteno JF (2019) Risk factors associated with drug resistant focal epilepsy in adults\u202f: A case control study. Seizure Eur J Epilepsy 73:46\u201350. https:\/\/doi.org\/10.1016\/j.seizure.2019.10.020","journal-title":"Seizure Eur J Epilepsy"},{"key":"14012_CR3","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2023.106045","author":"RS Fisher","year":"2023","unstructured":"Fisher RS (2023) Deep brain stimulation of thalamus for epilepsy. Neurobiol Dis. https:\/\/doi.org\/10.1016\/j.nbd.2023.106045","journal-title":"Neurobiol Dis"},{"key":"14012_CR4","doi-asserted-by":"publisher","first-page":"256","DOI":"10.5603\/PJNNS.98258","volume":"58","author":"M Sobstyl","year":"2024","unstructured":"Sobstyl M, Konopko M, Wierzbicka A et al (2024) Deep brain stimulation of anterior nucleus and centromedian nucleus of thalamus in treatment for drug-resistant epilepsy. Neurol Neurochir Pol 58:256\u2013273. https:\/\/doi.org\/10.5603\/PJNNS.98258","journal-title":"Neurol Neurochir Pol"},{"key":"14012_CR5","doi-asserted-by":"publisher","DOI":"10.1016\/j.eplepsyres.2023.107199","author":"M Sobstyl","year":"2023","unstructured":"Sobstyl M, Konopko M, Sienkiewicz-Jarosz H et al (2023) Clinical efficacy and safety of anterior thalamic deep brain stimulation for intractable drug resistant epilepsy. Epilepsy Res. https:\/\/doi.org\/10.1016\/j.eplepsyres.2023.107199","journal-title":"Epilepsy Res"},{"key":"14012_CR6","doi-asserted-by":"publisher","first-page":"e99","DOI":"10.1111\/epi.13045","volume":"56","author":"BR Voges","year":"2015","unstructured":"Voges BR, Schmitt FC, Hamel W et al (2015) Deep brain stimulation of anterior nucleus thalami disrupts sleep in epilepsy patients. Epilepsia 56:e99\u2013e103. https:\/\/doi.org\/10.1111\/epi.13045","journal-title":"Epilepsia"},{"key":"14012_CR7","doi-asserted-by":"publisher","first-page":"2044","DOI":"10.1111\/epi.17657","volume":"64","author":"JC Buenzli","year":"2023","unstructured":"Buenzli JC, Werth E, Baumann CR et al (2023) Deep brain stimulation of the anterior nucleus of the thalamus increases slow wave activity in non-rapid eye movement sleep. Epilepsia 64:2044\u20132055. https:\/\/doi.org\/10.1111\/epi.17657","journal-title":"Epilepsia"},{"key":"14012_CR8","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fnhum.2024.1392100","volume":"18","author":"S Suresh","year":"2024","unstructured":"Suresh S, Chaitanya G, Kachhvah AD et al (2024) Case report: nocturnal low-frequency stimulation of the centromedian thalamic nucleus improves sleep quality and seizure control. Front Hum Neurosci 18:1\u20137. https:\/\/doi.org\/10.3389\/fnhum.2024.1392100","journal-title":"Front Hum Neurosci"},{"key":"14012_CR9","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1152\/physiol.00062.2015","volume":"32","author":"MJ Prerau","year":"2017","unstructured":"Prerau MJ, Brown RE, Bianchi MT et al (2017) Sleep neurophysiological dynamics through the lens of multitaper spectral analysis. Physiology (Bethesda) 32:60\u201392. https:\/\/doi.org\/10.1152\/physiol.00062.2015","journal-title":"Physiology (Bethesda)"},{"key":"14012_CR10","doi-asserted-by":"publisher","DOI":"10.3389\/FNINS.2021.803507","volume":"15","author":"S Long","year":"2021","unstructured":"Long S, Ding R, Wang J et al (2021) Sleep quality and electroencephalogram delta power. Front Neurosci 15:803507. https:\/\/doi.org\/10.3389\/FNINS.2021.803507","journal-title":"Front Neurosci"},{"key":"14012_CR11","doi-asserted-by":"publisher","first-page":"1480819","DOI":"10.3389\/FNEUR.2024.1480819\/BIBTEX","volume":"15","author":"F Pizzo","year":"2024","unstructured":"Pizzo F, Carron R, Laguitton V et al (2024) Medial pulvinar stimulation for focal drug-resistant epilepsy: interim 12-month results of the PULSE study. Front Neurol 15:1480819. https:\/\/doi.org\/10.3389\/FNEUR.2024.1480819\/BIBTEX","journal-title":"Front Neurol"},{"issue":"1","key":"14012_CR12","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1002\/slp2.12","volume":"1","author":"Y Zhang","year":"2024","unstructured":"Zhang Y, Chen K, Xu Y et al (2024) Research progress on the first-night effect in polysomnography studies. Sleep Res 1(1):19\u201326. https:\/\/doi.org\/10.1002\/slp2.12","journal-title":"Sleep Res"},{"key":"14012_CR13","doi-asserted-by":"publisher","first-page":"233","DOI":"10.3390\/brainsci12020233","volume":"12","author":"A Mayeli","year":"2022","unstructured":"Mayeli A, Janssen SA, Sharma K et al (2022) First Night Effect on Sleep Parameters with hd-EEG in Healthy Individuals. Brain Sci 12:233. https:\/\/doi.org\/10.3390\/brainsci12020233","journal-title":"Brain Sci"},{"key":"14012_CR14","doi-asserted-by":"publisher","first-page":"630","DOI":"10.1097\/WNP.0000000000001060","volume":"41","author":"D Burdette","year":"2024","unstructured":"Burdette D, Patra S, Johnson L (2024) Corticothalamic responsive neurostimulation for focal epilepsy: a single-center experience. J Clin Neurophysiol 41:630\u2013639. https:\/\/doi.org\/10.1097\/WNP.0000000000001060","journal-title":"J Clin Neurophysiol"},{"key":"14012_CR15","doi-asserted-by":"publisher","first-page":"314","DOI":"10.1111\/JON.12952","volume":"32","author":"E Santarnecchi","year":"2021","unstructured":"Santarnecchi E, Sprugnoli G, Sicilia I et al (2021) Thalamic altered spontaneous activity and connectivity in obstructive sleep apnea syndrome. J Neuroimaging 32:314. https:\/\/doi.org\/10.1111\/JON.12952","journal-title":"J Neuroimaging"},{"key":"14012_CR16","doi-asserted-by":"publisher","first-page":"687","DOI":"10.1016\/J.NEUROL.2023.07.006","volume":"179","author":"N El Youssef","year":"2023","unstructured":"El Youssef N, Marchi A, Bartolomei F et al (2023) Sleep and epilepsy: a clinical and pathophysiological overview. Rev Neurol (Paris) 179:687\u2013702. https:\/\/doi.org\/10.1016\/J.NEUROL.2023.07.006","journal-title":"Rev Neurol (Paris)"},{"key":"14012_CR17","doi-asserted-by":"publisher","DOI":"10.7759\/CUREUS.6901","author":"P Gurung","year":"2020","unstructured":"Gurung P, Nene Y, Sivaraman M (2020) Vagus nerve stimulator (VNS)-induced severe obstructive sleep apnea which resolved after the VNS was turned off. Cureus. https:\/\/doi.org\/10.7759\/CUREUS.6901","journal-title":"Cureus"},{"key":"14012_CR18","first-page":"105","volume":"15","author":"M Goyal","year":"2023","unstructured":"Goyal M, Mishra P, Jaseja H (2023) Obstructive sleep apnea and epilepsy: understanding the pathophysiology of the comorbidity. Int J Physiol Pathophysiol Pharmacol 15:105","journal-title":"Int J Physiol Pathophysiol Pharmacol"},{"key":"14012_CR19","doi-asserted-by":"publisher","first-page":"393","DOI":"10.3233\/JPD-191862","volume":"10","author":"JRP Zuzu\u00e1rregui","year":"2020","unstructured":"Zuzu\u00e1rregui JRP, Ostrem JL (2020) The impact of deep brain stimulation on sleep in Parkinson\u2019s disease: an update. J Parkinsons Dis 10:393\u2013404. https:\/\/doi.org\/10.3233\/JPD-191862","journal-title":"J Parkinsons Dis"},{"key":"14012_CR20","doi-asserted-by":"publisher","first-page":"1269864","DOI":"10.3389\/FNHUM.2023.1269864\/BIBTEX","volume":"17","author":"AA Memon","year":"2023","unstructured":"Memon AA, Edney BS, Baumgartner AJ et al (2023) Effects of deep brain stimulation on quantitative sleep electroencephalogram during non-rapid eye movement in Parkinson\u2019s disease. Front Hum Neurosci 17:1269864. https:\/\/doi.org\/10.3389\/FNHUM.2023.1269864\/BIBTEX","journal-title":"Front Hum Neurosci"},{"key":"14012_CR21","doi-asserted-by":"publisher","first-page":"1671","DOI":"10.1152\/JN.00915.2004","volume":"93","author":"S Hill","year":"2005","unstructured":"Hill S, Tononi G (2005) Modeling sleep and wakefulness in the thalamocortical system. J Neurophysiol 93:1671\u20131698. https:\/\/doi.org\/10.1152\/JN.00915.2004","journal-title":"J Neurophysiol"},{"key":"14012_CR22","doi-asserted-by":"publisher","DOI":"10.1038\/S42003-025-09205-2","volume":"8","author":"F Lu","year":"2025","unstructured":"Lu F, Wang J, Qin X et al (2025) Differential engagement of thalamic nuclei orchestrates consciousness states across anesthesia, sleep, and disorders of consciousness. Commun Biol 8:1784. https:\/\/doi.org\/10.1038\/S42003-025-09205-2","journal-title":"Commun Biol"},{"key":"14012_CR23","doi-asserted-by":"publisher","first-page":"1797","DOI":"10.1093\/CERCOR\/BHZ203","volume":"30","author":"J Homman-Ludiye","year":"2020","unstructured":"Homman-Ludiye J, Mundinano IC, Kwan WC, Bourne JA (2020) Extensive connectivity between the medial pulvinar and the cortex revealed in the marmoset monkey. Cereb Cortex 30:1797\u20131812. https:\/\/doi.org\/10.1093\/CERCOR\/BHZ203","journal-title":"Cereb Cortex"},{"key":"14012_CR24","doi-asserted-by":"publisher","first-page":"1462","DOI":"10.1093\/CERCOR\/BHN185","volume":"19","author":"DS Rosenberg","year":"2009","unstructured":"Rosenberg DS, Maugui\u00e8re F, Catenoix H et al (2009) Reciprocal thalamocortical connectivity of the medial pulvinar: a depth stimulation and evoked potential study in human brain. Cereb Cortex 19:1462\u20131473. https:\/\/doi.org\/10.1093\/CERCOR\/BHN185","journal-title":"Cereb Cortex"},{"key":"14012_CR25","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/j.neuron.2015.11.034","volume":"89","author":"H Zhou","year":"2016","unstructured":"Zhou H, Schafer RJ, Desimone R (2016) Pulvinar-cortex interactions in vision and attention. Neuron 89:209\u2013220. https:\/\/doi.org\/10.1016\/j.neuron.2015.11.034","journal-title":"Neuron"},{"key":"14012_CR26","doi-asserted-by":"publisher","first-page":"e280","DOI":"10.1212\/WNL.0000000000011003","volume":"96","author":"F Pizzo","year":"2021","unstructured":"Pizzo F, Roehri N, Giusiano B et al (2021) The Ictal Signature of Thalamus and Basal Ganglia in Focal Epilepsy. Neurology 96:e280\u2013e293. https:\/\/doi.org\/10.1212\/WNL.0000000000011003","journal-title":"Neurology"},{"key":"14012_CR27","doi-asserted-by":"publisher","first-page":"858","DOI":"10.1093\/cercor\/bhh044","volume":"14","author":"M Magnin","year":"2004","unstructured":"Magnin M, Bastuji H, Garcia-Larrea L, Maugui\u00e8re F (2004) Human thalamic medial pulvinar nucleus is not activated during paradoxical sleep. Cereb Cortex 14:858\u2013862. https:\/\/doi.org\/10.1093\/cercor\/bhh044","journal-title":"Cereb Cortex"},{"key":"14012_CR28","doi-asserted-by":"publisher","first-page":"934","DOI":"10.1002\/GPS.5315","volume":"35","author":"H Kanemoto","year":"2020","unstructured":"Kanemoto H, Kazui H, Adachi H et al (2020) Thalamic pulvinar metabolism, sleep disturbances, and hallucinations in dementia with Lewy bodies: positron emission tomography and actigraphy study. Int J Geriatr Psychiatry 35:934\u2013943. https:\/\/doi.org\/10.1002\/GPS.5315","journal-title":"Int J Geriatr Psychiatry"},{"key":"14012_CR29","doi-asserted-by":"publisher","first-page":"13164","DOI":"10.1073\/PNAS.0703084104","volume":"104","author":"M Schabus","year":"2007","unstructured":"Schabus M, Dang-Vu TT, Albouy G et al (2007) Hemodynamic cerebral correlates of sleep spindles during human non-rapid eye movement sleep. Proc Natl Acad Sci U S A 104:13164\u201313169. https:\/\/doi.org\/10.1073\/PNAS.0703084104","journal-title":"Proc Natl Acad Sci U S A"},{"key":"14012_CR30","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-32840-w","author":"T Schreiner","year":"2022","unstructured":"Schreiner T, Kaufmann E, Noachtar S et al (2022) The human thalamus orchestrates neocortical oscillations during NREM sleep. Nat Commun. https:\/\/doi.org\/10.1038\/s41467-022-32840-w","journal-title":"Nat Commun"},{"key":"14012_CR31","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms15499","author":"RA Mak-Mccully","year":"2017","unstructured":"Mak-Mccully RA, Rolland M, Sargsyan A et al (2017) Coordination of cortical and thalamic activity during non-REM sleep in humans. Nat Commun. https:\/\/doi.org\/10.1038\/ncomms15499","journal-title":"Nat Commun"},{"key":"14012_CR32","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-33010-8","author":"B Setzer","year":"2022","unstructured":"Setzer B, Fultz NE, Gomez DEP et al (2022) A temporal sequence of thalamic activity unfolds at transitions in behavioral arousal state. Nat Commun. https:\/\/doi.org\/10.1038\/s41467-022-33010-8","journal-title":"Nat Commun"},{"key":"14012_CR33","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2023.108041","volume":"235","author":"GM Wong","year":"2023","unstructured":"Wong GM, Hofmann K, Shlobin NA et al (2023) Stimulation of the pulvinar nucleus of the thalamus in epilepsy: a systematic review and individual patient data (IPD) analysis. Clin Neurol Neurosurg 235:108041. https:\/\/doi.org\/10.1016\/j.clineuro.2023.108041","journal-title":"Clin Neurol Neurosurg"},{"key":"14012_CR34","doi-asserted-by":"publisher","DOI":"10.1126\/science.adr3339","author":"N Kharas","year":"2024","unstructured":"Kharas N, Chelaru MI, Eagleman S et al (2024) NREM sleep improves behavioral performance by desynchronizing cortical circuits. Neuroscience. https:\/\/doi.org\/10.1126\/science.adr3339","journal-title":"Neuroscience"}],"container-title":["Journal of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00415-026-14012-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00415-026-14012-8","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00415-026-14012-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,10]],"date-time":"2026-08-10T07:49:14Z","timestamp":1786348154000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00415-026-14012-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,23]]},"references-count":34,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["14012"],"URL":"https:\/\/doi.org\/10.1007\/s00415-026-14012-8","relation":{},"ISSN":["0340-5354","1432-1459"],"issn-type":[{"value":"0340-5354","type":"print"},{"value":"1432-1459","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,23]]},"assertion":[{"value":"13 April 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 July 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 July 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 July 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"None of the authors have potential conflicts of interest to be disclosed. All the authors have approved the final article.","order":1,"name":"Ethics","label":"Conflict of interests","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was conducted in accordance with the Declaration of Helsinki and approved by the local ethical committee (\u201cComit\u00e9 d\u2019Ethique et Scientifique\u2014CSE\u2014de l\u2019AP-HM) (PADS26-26). Informed consent was obtained from all subjects involved in the study.","order":2,"name":"Ethics","label":"Informed consent","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"484"}}