{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T12:52:35Z","timestamp":1778158355001,"version":"3.51.4"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2005,10,16]],"date-time":"2005-10-16T00:00:00Z","timestamp":1129420800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Graefe's Arch Clin Exp Ophthalmo"],"published-print":{"date-parts":[[2006,6]]},"DOI":"10.1007\/s00417-005-0138-9","type":"journal-article","created":{"date-parts":[[2005,10,15]],"date-time":"2005-10-15T09:38:57Z","timestamp":1129369137000},"page":"663-669","source":"Crossref","is-referenced-by-count":78,"title":["Intraocular lymphoma 2000\u20132005: results of a retrospective multicentre trial"],"prefix":"10.1007","volume":"244","author":[{"given":"Kristoph","family":"Jahnke","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agnieszka","family":"Korfel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julia","family":"Komm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikolaos E.","family":"Bechrakis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harald","family":"Stein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eckhard","family":"Thiel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah E.","family":"Coupland","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2005,10,16]]},"reference":[{"key":"138_CR1","doi-asserted-by":"crossref","first-page":"1805","DOI":"10.1016\/S0161-6420(99)90341-X","volume":"106","author":"EK Akpek","year":"1999","unstructured":"Akpek EK, Ahmed I, Hochberg FH, Soheilian M, Dryja TP, Jakobiec FA, Foster CS (1999) Intraocular-central nervous system lymphoma. Clinical features, diagnosis and outcome. Ophthamology 106:1805\u20131810","journal-title":"Ophthamology"},{"key":"138_CR2","first-page":"224","volume":"19","author":"CC Barr","year":"1975","unstructured":"Barr CC, Green WR, Payne JW, Knox DL, Jensen AD, Thompson RL (1975) Intraocular reticulum-cell sarcoma: clinicopathologic study of four cases and review of the literature. Surv Ophthalmol 19:224\u2013239","journal-title":"Surv Ophthalmol"},{"key":"138_CR3","first-page":"711","volume":"9","author":"TT Batchelor","year":"2003","unstructured":"Batchelor TT, Kolak G, Ciordia R, Foster CS, Henson JW (2003) High-dose methotrexate for intraocular lymphoma. Clin Cancer Res 9:711\u2013715","journal-title":"Clin Cancer Res"},{"key":"138_CR4","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1200\/JCO.1998.16.3.864","volume":"16","author":"JY Blay","year":"1998","unstructured":"Blay JY, Conroy T, Chevreau C, Thyss A, Quesnel N, Eghbali H, Bouabdallah R, Coiffier B, Wagner JP, Le Mevel A, Dramais-Marcel D, Baumelou E, Chauvin F, Biron P (1998) High-dose methotrexate for the treatment of primary cerebral lymphomas: analysis of survival and late neurologic toxicity in a retrospective series. J Clin Oncol 16:864\u2013871","journal-title":"J Clin Oncol"},{"key":"138_CR5","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1097\/00001622-200105000-00001","volume":"13","author":"RR Buggage","year":"2001","unstructured":"Buggage RR, Chan CC, Nussenblatt RB (2001) Ocular manifestations of central nervous system lymphoma. Curr Opin Oncol 13:137\u2013142","journal-title":"Curr Opin Oncol"},{"key":"138_CR6","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1076\/ocii.8.4.243.6463","volume":"8","author":"N Cassoux","year":"2000","unstructured":"Cassoux N, Merle-Beral H, Leblond V, Bodaghi B, Milea D, Gerber S, Fardeau C, Reux I, Xuan KH, Chan CC, LeHoang P (2000) Ocular and central nervous system lymphoma: clinical features and diagnosis. Ocul Immunol Inflamm 8:243\u2013250","journal-title":"Ocul Immunol Inflamm"},{"key":"138_CR7","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/S0161-6420(88)33145-3","volume":"95","author":"DH Char","year":"1988","unstructured":"Char DH, Ljung BM, Miller T, Phillips T (1988) Primary intraocular lymphoma (ocular reticulum cell sarcoma) diagnosis and management. Ophthalmology 95:625\u2013630","journal-title":"Ophthalmology"},{"key":"138_CR8","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1007\/s00417-003-0749-y","volume":"241","author":"SE Coupland","year":"2003","unstructured":"Coupland SE, Bechrakis NE, Anastassiou G, Foerster A, Heiligenhaus A, Pleyer U, Hummel M, Stein H (2003) Evaluation of vitrectomy specimens and chorioretinal biopsies in the diagnostic of primary intraocular lymphoma in patients with Masquerade syndrome. Graefe Arch Clin Exp Ophthalmol 241:860\u2013870","journal-title":"Graefe Arch Clin Exp Ophthalmol"},{"key":"138_CR9","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1007\/s00417-004-0973-0","volume":"242","author":"SE Coupland","year":"2004","unstructured":"Coupland SE, Heimann H, Bechrakis NE (2004) Primary intraocular lymphoma: a review of the clinical, histopathological and molecular biological features. Graefe Arch Clin Exp Ophthalmol 242:901\u2013913","journal-title":"Graefe Arch Clin Exp Ophthalmol"},{"key":"138_CR10","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1136\/bjo.2004.047001","volume":"89","author":"SE Coupland","year":"2005","unstructured":"Coupland SE, Hummel M, Stein H, Willerding G, Jahnke K, Stoltenburg-Didinger G (2005) Demonstration of identical clonal derivation in a case of \u201coculocerebral\u201d lymphoma. Br J Ophthalmol 89:238\u2013239","journal-title":"Br J Ophthalmol"},{"key":"138_CR11","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1076\/ocii.12.1.7.28072","volume":"12","author":"JL Davis","year":"2004","unstructured":"Davis JL (2004) Diagnosis of intraocular lymphoma. Ocul Immunol Inflamm 12:7\u201316","journal-title":"Ocul Immunol Inflamm"},{"key":"138_CR12","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1053\/j.seminoncol.2004.07.011","volume":"31","author":"LM DeAngelis","year":"2004","unstructured":"DeAngelis LM, Hormigo A (2004) Treatment of primary central nervous system lymphoma. Semin Oncol 31:684\u2013692","journal-title":"Semin Oncol"},{"key":"138_CR13","first-page":"2641","volume":"62","author":"NL Eby","year":"1988","unstructured":"Eby NL, Grufferman S, Flannelly CM, Schold SC Jr, Vogel FS, Burger PC (1988) Increasing incidence of primary brain lymphoma in the U.S. Cancer 62:2641\u20132665","journal-title":"Cancer"},{"key":"138_CR14","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1093\/annonc\/mdf080","volume":"13","author":"AJ Ferreri","year":"2002","unstructured":"Ferreri AJ, Blay JY, Reni M, Pasini F, Gubkin A, Tirelli U, Calderoni A, Zucca E, Cortelazzo S, Chassagne C, Tinguel M, Borisch B, Berger F, Ponzoni M, Cavalli F; International Extranodal Lymphoma Study Group (IELSG) (2002) Relevance of intraocular involvement in the management of primary central nervous system lymphomas. Ann Oncol 13:531\u2013538","journal-title":"Ann Oncol"},{"key":"138_CR15","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1200\/JCO.2003.09.139","volume":"21","author":"AJ Ferreri","year":"2003","unstructured":"Ferreri AJ, Blay JY, Reni M, Pasini F, Spina M, Ambrosetti A, Calderoni A, Rossi A, Vavassori V, Conconi A, Devizzi L, Berger F, Ponzoni M, Borisch B, Tinguely M, Cerati M, Milani M, Orvieto E, Sanchez J, Chevreau C, Dell'Oro S, Zucca E, Cavalli F (2003) Prognostic scoring system for primary CNS lymphomas: the International Extranodal Lymphoma Study Group Experience. J Clin Oncol 21:266\u2013272","journal-title":"J Clin Oncol"},{"key":"138_CR16","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.7326\/0003-4819-119-11-199312010-00007","volume":"119","author":"HA Fine","year":"1993","unstructured":"Fine HA, Mayer RJ (1993) Primary central nervous system lymphoma. Ann Intern Med 119:1093\u20131104","journal-title":"Ann Intern Med"},{"key":"138_CR17","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1038\/sj.eye.6700378","volume":"17","author":"PM Hoffman","year":"2003","unstructured":"Hoffman PM, McKelvie P, Hall AJ, Stawell RJ, Santamaria JD (2003) Intraocular lymphoma: a series of 14 patients with clinicopathological features and treatment outcomes. Eye 17:513\u2013521","journal-title":"Eye"},{"key":"138_CR18","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1111\/j.1365-2141.2004.05028.x","volume":"126","author":"A Hormigo","year":"2004","unstructured":"Hormigo A, Abrey L, Heinemann MH, DeAngelis LM (2004) Ocular presentation of primary central nervous system lymphoma: diagnosis and treatment. Br J Haematol 126:202\u2013208","journal-title":"Br J Haematol"},{"key":"138_CR19","volume-title":"World Health Organization classification of tumours. Pathology and genetics of tumours of haematopoietic and lymphoid tissues","author":"ES Jaffe","year":"2001","unstructured":"Jaffe ES, Harris NL, Stein H, Vardiman JW (2001) World Health Organization classification of tumours. Pathology and genetics of tumours of haematopoietic and lymphoid tissues. IARC Press, Lyon"},{"key":"138_CR20","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1007\/s00417-004-0947-2","volume":"242","author":"K Jahnke","year":"2004","unstructured":"Jahnke K, Bechrakis NE, Coupland SE, Schmittel A, Foerster MH, Fischer L, Thiel E, Korfel A (2004) Treatment of primary intraocular lymphoma with oral trofosfamide: report of two cases and review of the literature. Graefe Arch Clin Exp Ophthalmol 242:771\u2013776","journal-title":"Graefe Arch Clin Exp Ophthalmol"},{"key":"138_CR21","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1002\/1097-0142(20000915)89:6<1359::AID-CNCR21>3.0.CO;2-9","volume":"89","author":"GM Mead","year":"2000","unstructured":"Mead GM, Bleehen NM, Gregor A, Bullimore J, Shirley D, Rampling RP, Trevor J, Glaser MG, Lantos P, Ironside JW, Moss TH, Brada M, Whaley JB, Stenning SP (2000) A medical research council randomized trial in patients with primary cerebral non-Hodgkin lymphoma: cerebral radiotherapy with and without cyclophosphamide, doxorubicin, vincristine, and prednisone chemotherapy. Cancer 89:1359\u20131370","journal-title":"Cancer"},{"key":"138_CR22","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1016\/S0360-3016(98)00450-7","volume":"43","author":"BP O'Neill","year":"1999","unstructured":"O'Neill BP, Wang CH, O'Fallon JR, Colgan JD, Earle JD, Krigel RL, Brown LD, McGinnis WL (1999) Primary central nervous system non-Hodgkin's lymphoma (PCNSL): survival advantages with combined initial therapy? A final report of the North Central Cancer Treatment Group (NCCTG) Study 86-72-52. Int J Radiat Oncol Biol Phys 43:559\u2013563","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"138_CR23","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1002\/1097-0142(19930801)72:3<843::AID-CNCR2820720333>3.0.CO;2-#","volume":"72","author":"K Peterson","year":"1993","unstructured":"Peterson K, Gordon KB, Heinemann MH, DeAngelis L (1993) The clinical spectrum of ocular lymphoma. Cancer 72:843\u2013849","journal-title":"Cancer"},{"key":"138_CR24","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/S0161-6420(00)00499-1","volume":"108","author":"A Rothova","year":"2001","unstructured":"Rothova A, Ooijman F, Kerkhoff F, Van Der Lelij A, Lokhorst HM (2001) Uveitis masquerade syndromes. Ophthalmology 108:386\u2013399","journal-title":"Ophthalmology"},{"key":"138_CR25","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1200\/JCO.1996.14.2.556","volume":"14","author":"C Schultz","year":"1996","unstructured":"Schultz C, Scott C, Sherman W, Donahue B, Fields J, Murray K, Fisher B, Abrams R, Meis-Kindblom J (1996) Preirradiation chemotherapy with cyclophosphamide, doxorubicin, vincristine, and dexamethasone for primary CNS lymphomas: initial report of radiation therapy oncology group protocol 88-06. J Clin Oncol 14:556\u2013564","journal-title":"J Clin Oncol"},{"key":"138_CR26","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1016\/S0161-6420(02)01125-9","volume":"109","author":"JR Smith","year":"2002","unstructured":"Smith JR, Rosenbaum JT, Wilson DJ, Doolittle ND, Siegal T, Neuwelt EA, Pe'er J (2002) Role of intravitreal methotrexate in the management of primary central nervous system lymphoma with ocular involvement. Ophthalmology 109:1709\u20131716","journal-title":"Ophthalmology"},{"key":"138_CR27","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1200\/JCO.2001.19.3.742","volume":"19","author":"C Soussain","year":"2001","unstructured":"Soussain C, Suzan F, Hoang-Xuan K, Cassoux N, Levy V, Azar N, Belanger C, Achour E, Ribrag V, Gerber S, Delattre JY, Leblond V (2001) Results of intensive chemotherapy followed by hematopoietic stem-cell rescue in 22 patients with refractory or recurrent primary CNS lymphoma or intraocular lymphoma. J Clin Oncol 19:742\u2013749","journal-title":"J Clin Oncol"},{"key":"138_CR28","doi-asserted-by":"crossref","first-page":"1918","DOI":"10.1002\/1097-0142(19890515)63:10<1918::AID-CNCR2820631008>3.0.CO;2-D","volume":"63","author":"JA Strauchen","year":"1989","unstructured":"Strauchen JA, Dalton J, Friedman AH (1989) Chemotherapy in the management of intraocular lymphoma. Cancer 63:1918\u20131921","journal-title":"Cancer"},{"key":"138_CR29","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1097\/00001813-199706000-00002","volume":"8","author":"A Wagner","year":"1997","unstructured":"Wagner A, Hempel G, Boos J (1997) Trofosfamide: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the oral treatment of cancer. Anticancer Drugs 8:419\u2013431","journal-title":"Anticancer Drugs"},{"key":"138_CR30","doi-asserted-by":"crossref","first-page":"1399","DOI":"10.1016\/S0161-6420(93)31469-7","volume":"100","author":"SM Whitcup","year":"1993","unstructured":"Whitcup SM, de Smet MD, Rubin BI, Palestine AG, Martin DF, Burnier M Jr, Chan CC, Nussenblatt RB (1993) Intraocular lymphoma. Clinical and histopathologic diagnosis. Ophthalmology 100:1399\u20131406","journal-title":"Ophthalmology"},{"key":"138_CR31","first-page":"1985","volume":"3","author":"SM Yule","year":"1997","unstructured":"Yule SM, Price L, Pearson AD, Boddy AV (1997) Cyclophosphamide and ifosfamide metabolites in the cerebrospinal fluid of children. Clin Cancer Res 3:1985\u20131992","journal-title":"Clin Cancer Res"},{"key":"138_CR32","first-page":"1762","volume":"111","author":"RA Zaldivar","year":"2004","unstructured":"Zaldivar RA, Martin DF, Holden JT, Grossniklaus HE (2004) Primary intraocular lymphoma: clinical, cytologic, and flow cytometric analysis. Ophthalmology 111:1762\u20131767","journal-title":"Ophthalmology"}],"container-title":["Graefe's Archive for Clinical and Experimental Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00417-005-0138-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00417-005-0138-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00417-005-0138-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T15:30:34Z","timestamp":1559057434000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00417-005-0138-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,10,16]]},"references-count":32,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2006,6]]}},"alternative-id":["138"],"URL":"https:\/\/doi.org\/10.1007\/s00417-005-0138-9","relation":{},"ISSN":["0721-832X","1435-702X"],"issn-type":[{"value":"0721-832X","type":"print"},{"value":"1435-702X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,10,16]]}}}