{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T21:01:14Z","timestamp":1792098074657,"version":"4.4.0"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2013,3,1]],"date-time":"2013-03-01T00:00:00Z","timestamp":1362096000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Graefes Arch Clin Exp Ophthalmol"],"published-print":{"date-parts":[[2013,6]]},"DOI":"10.1007\/s00417-013-2275-x","type":"journal-article","created":{"date-parts":[[2013,2,28]],"date-time":"2013-02-28T22:25:13Z","timestamp":1362090313000},"page":"1601-1606","source":"Crossref","is-referenced-by-count":40,"title":["Adalimumab for juvenile idiopathic arthritis-associated uveitis"],"prefix":"10.1007","volume":"251","author":[{"given":"Adriano","family":"Magli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raimondo","family":"Forte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pasqualina","family":"Navarro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giustina","family":"Russo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Orlando","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loredana","family":"Latanza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Alessio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2013,3,1]]},"reference":[{"issue":"Suppl","key":"2275_CR1","first-page":"6","volume":"33","author":"JE Levinson","year":"1992","unstructured":"Levinson JE, Wallace CA (1992) Dismantling the pyramid. J Rheumatol 33(Suppl):6\u201310","journal-title":"J Rheumatol"},{"key":"2275_CR2","first-page":"945","volume":"24","author":"N Ruperto","year":"1997","unstructured":"Ruperto N, Levinson JE, Ravelli A, Shear ES, Link Tague B, Murray K, Martini A, Giannini EH (1997) Long term health outcomes and quality of life in American and Italian inception cohorts of patients with juvenile rheumatoid arthritis. I. Outcome status. J Rheumatol 24:945\u2013951","journal-title":"J Rheumatol"},{"key":"2275_CR3","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/0039-6257(90)90026-R","volume":"34","author":"JJ Kanski","year":"1990","unstructured":"Kanski JJ (1990) Juvenile arthritis and uveitis. Surv Ophthalmol 34:253\u2013267","journal-title":"Surv Ophthalmol"},{"key":"2275_CR4","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/S0039-6257(03)00084-5","volume":"48","author":"K Kotaniemi","year":"2003","unstructured":"Kotaniemi K, Savolainen A, Karma A, Aho K (2003) Major review. Recent advances in uveitis of juvenile idiopathic arthritis. Surv Ophthalmol 48:489\u2013502","journal-title":"Surv Ophthalmol"},{"key":"2275_CR5","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/j.1755-3768.2009.01815.x","volume":"90","author":"ME Zannin","year":"2012","unstructured":"Zannin ME, Buscain I, Vittadello F, Martini G, Alessio M, Orsoni JG, Breda L, Rigante D, Cimaz R, Zulian F (2012) Timing of uveitis onset in oligoarticular juvenile idiopathic arthritis (JIA) is the main predictor of severe course uveitis. Acta Ophthalmol 90:91\u201395","journal-title":"Acta Ophthalmol"},{"key":"2275_CR6","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1159\/000055677","volume":"33","author":"M Santos Lacomba","year":"2001","unstructured":"Santos Lacomba M, Marcos Mart\u00edn C, Gallardo Galera JM, G\u00f3mez Vidal MA, Collantes Est\u00e9vez E, Ram\u00edrez Chamond R, Omar M (2001) Aqueous humor and serum tumor necrosis factor-alpha in clinical uveitis. Ophthalmic Res 33:251\u2013255","journal-title":"Ophthalmic Res"},{"key":"2275_CR7","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1002\/1529-0131(200106)45:3<252::AID-ART257>3.0.CO;2-5","volume":"45","author":"JR Smith","year":"2001","unstructured":"Smith JR, Levinson RD, Holland GN, Jabs DA, Robinson MR, Whitcup SM, Rosenbaum JT (2001) Differential efficacy of tumor necrosis factor inhibition in the management of inflammatory eye disease and associated rheumatic disease. Arthritis Rheum 45:252\u2013257","journal-title":"Arthritis Rheum"},{"key":"2275_CR8","doi-asserted-by":"crossref","first-page":"137","DOI":"10.2165\/00148581-200406030-00001","volume":"6","author":"D Lovell","year":"2004","unstructured":"Lovell D (2004) Biological agents for the treatment of juvenile rheumatoid arthritis: current status. Paediatric Drugs 6:137\u2013146","journal-title":"Paediatric Drugs"},{"key":"2275_CR9","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/s10067-007-0654-6","volume":"27","author":"G Gartlehner","year":"2008","unstructured":"Gartlehner G, Hansen RA, Jonas BL, Thieda P, Lohr KN (2008) Biologics for the treatment of juvenile idiopathic arthritis: a systemic review and critical analysis of the evidence. Clin Rheumatol 27:67\u201376","journal-title":"Clin Rheumatol"},{"key":"2275_CR10","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1136\/adc.2009.170860","volume":"94","author":"MW Beresford","year":"2009","unstructured":"Beresford MW, Baildam EM (2009) New advances in the management of juvenile idiopathic arthritis. 2: the era of biologicals. Arch Dis Child Educ Pract Ed 94:151\u2013156","journal-title":"Arch Dis Child Educ Pract Ed"},{"key":"2275_CR11","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.1002\/art.23427","volume":"58","author":"DJ Lovell","year":"2008","unstructured":"Lovell DJ, Reiff A, Ilowite NT, Wallace CA, Chon Y, Lin SL, Baumgartner SW, Giannini EH, Pediatric Rheumatology Collaborative Study Group (2008) Safety and efficacy of up to eight years of continuous etanercept therapy in patients with juvenile idiopathic arthritis. Arthritis Rheum 58:1496\u20131504","journal-title":"Arthritis Rheum"},{"key":"2275_CR12","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1136\/ard.2007.087593","volume":"68","author":"G Horneff","year":"2009","unstructured":"Horneff G, De Bock F, Foeldvari I, Girschick HJ, Michels H, Moebius D, Schmeling H, German and Austrian Paediatric Rheumatology Collaborative Study Group (2009) Safety and efficacy of combination of etanercept and methotrexate compared to treatment with etanercept only in patients with juvenile idiopathic arthritis (JIA): preliminary data from the German registry. Ann Rheum Dis 68:519\u2013525","journal-title":"Ann Rheum Dis"},{"key":"2275_CR13","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1136\/ard.2007.087411","volume":"68","author":"FH Prince","year":"2009","unstructured":"Prince FH, Twilt M, ten Cate R, van Rossum MA, Armbrust W, Hoppenreijs EP, van Santen-Hoeufft M, Koopman-Keemink Y, Wulffraat NM, van Suijlekom-Smit LW (2009) Long-term follow-up on effectiveness and safety of etanercept in JIA: the Dutch national register. Ann Rheum Dis 68:635\u2013641","journal-title":"Ann Rheum Dis"},{"key":"2275_CR14","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1136\/ard.2006.058248","volume":"66","author":"P Tynj\u00e4l\u00e4","year":"2007","unstructured":"Tynj\u00e4l\u00e4 P, Lindahl P, Honkanen V, Lahdenne P, Kotaniemi K (2007) Infliximab and etanercept in the treatment of chronic uveitis associated with refractory juvenile idiopathic arthritis. Ann Rheum Dis 66:548\u2013550","journal-title":"Ann Rheum Dis"},{"key":"2275_CR15","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1016\/j.ophtha.2006.01.005","volume":"113","author":"P Kahn","year":"2006","unstructured":"Kahn P, Weiss M, Imundo LF, Levy DM (2006) Favorable response to high-dose infliximab for refractory childhood uveitis. Ophthalmol 113:860\u2013864, Epub 15 March 2006","journal-title":"Ophthalmol"},{"key":"2275_CR16","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1001\/archopht.123.7.903","volume":"123","author":"EB Suhler","year":"2005","unstructured":"Suhler EB, Smith JR, Wertheim MS, Lauer AK, Kurz DE, Pickard TD, Rosenbaum JT (2005) A prospective trial of infliximab therapy for refractory uveitis: preliminary safety and efficacy outcomes. Arch Ophthalmol 123:903\u2013912","journal-title":"Arch Ophthalmol"},{"key":"2275_CR17","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/j.ophtha.2005.09.037","volume":"113","author":"RT Rajaraman","year":"2006","unstructured":"Rajaraman RT, Kimura Y, Li S, Haines K, Chu DS (2006) Retrospective case review of pediatric patients with uveitis treated with infliximab. Ophthalmology 113:308\u2013314","journal-title":"Ophthalmology"},{"key":"2275_CR18","doi-asserted-by":"crossref","unstructured":"Sukumaran S, Marzan K, Shaham B, Reiff A (2012) High dose infliximab in the treatment of refractory uveitis: does dose matter? Rheumatol Jan 5. doi: 10.5402\/2012\/765380","DOI":"10.5402\/2012\/765380"},{"key":"2275_CR19","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1136\/bjo.2006.103721","volume":"91","author":"S Biester","year":"2007","unstructured":"Biester S, Deuter C, Michels H, Haefner R, Kuemmerle-Deschner J, Doycheva D, Zierhut M (2007) Adalimumab in the therapy of uveitis in childhood. Br J Ophthalmol 91:319\u2013324","journal-title":"Br J Ophthalmol"},{"key":"2275_CR20","first-page":"1146","volume":"34","author":"I Foeldvari","year":"2007","unstructured":"Foeldvari I, Nielsen S, K\u00fcmmerle-Deschner J, Espada G, Horneff G, Bica B, Olivieri AN, Wierk A, Saurenmann RK (2007) Tumor necrosis factor-alpha blocker in treatment of juvenile idiopathic arthritis associated uveitis refractory to second-line agents: results of a multinational survey. J Rheumatol 34:1146\u20131150","journal-title":"J Rheumatol"},{"key":"2275_CR21","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1002\/1529-0131(199707)40:7<1202::AID-ART3>3.0.CO;2-R","volume":"40","author":"EH Giannini","year":"1997","unstructured":"Giannini EH, Ruperto N, Ravelli A, Lovell DJ, Felson DT, Martini A (1997) Preliminary definition of improvement in juvenile arthritis. Arthritis Rheum 40:1202\u20131209","journal-title":"Arthritis Rheum"},{"key":"2275_CR22","first-page":"1991","volume":"25","author":"RE Petty","year":"1998","unstructured":"Petty RE, Southwood TR, Baum J, Bhettay E, Glass DN, Manners P, Maldonado-Cocco J, Suarez-Almazor M, Orozco-Alcala J, Prieur AM (1998) Revision of the proposal classification criteria for juvenile idiopathic arthritis: Durban, 1997. J Rheumatol 25:1991\u20131994","journal-title":"J Rheumatol"},{"key":"2275_CR23","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/j.ajo.2005.03.057","volume":"140","author":"DA Jabs","year":"2005","unstructured":"Jabs DA, Nussenblatt RB, Rosenbaum JT (2005) Standardization of Uveitis Nomenclature (SUN) working group. Standardization of Uveitis Nomenclature for reporting clinical data. Results of the first international workshop. Am J Ophthalmol 140:509\u2013516","journal-title":"Am J Ophthalmol"},{"issue":"6","key":"2275_CR24","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1002\/acr.20115","volume":"62","author":"F Zulian","year":"2010","unstructured":"Zulian F, Balzarin M, Falcini F, Martini G, Alessio M, Cimaz R, Cimino L, Zannin ME (2010). Abatacept for severe anti-TNF alpha refractory juvenile idiopathic arthritis-related uveitis. Arthritis Care Res (Hoboken) 62(6):821\u2013825","journal-title":"Arthritis Care Res (Hoboken)"},{"key":"2275_CR25","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1016\/j.ophtha.2012.02.018","volume":"119","author":"M D\u00edaz-Llopis","year":"2012","unstructured":"D\u00edaz-Llopis M, Salom D, Garcia-de-Vicu\u00f1a C, Cordero-Coma M, Ortega G, Ortego N, Suarez-de-Figueroa M, Rio-Pardo MJ, Fernandez-Cid C, Fonollosa A, Blanco R, Garcia-Aparicio AM, Benitez-Del-Castillo JM, Olea JL, Arevalo JF (2012) Treatment of refractory uveitis with adalimumab: a prospective multicenter study of 131 patients. Ophthalmology 119:1575\u20131581","journal-title":"Ophthalmology"},{"key":"2275_CR26","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1093\/rheumatology\/kem356","volume":"47","author":"P Tynj\u00e4l\u00e4","year":"2008","unstructured":"Tynj\u00e4l\u00e4 P, Kotaniemi K, Lindahl P, Latva K, Aalto K, Honkanen V, Lahdenne P (2008) Adalimumab in juvenile idiopathic arthritis-associated chronic anterior uveitis. Rheumatology (Oxford) 47:339\u2013344","journal-title":"Rheumatology (Oxford)"},{"key":"2275_CR27","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.2147\/OPTH.S23646","volume":"5","author":"K Kotaniemi","year":"2011","unstructured":"Kotaniemi K, S\u00e4il\u00e4 H, Kautiainen H (2011) Long-term efficacy of adalimumab in the treatment of uveitis associated with juvenile idiopathic arthritis. Clin Ophthalmol 5:1425\u20131429","journal-title":"Clin Ophthalmol"},{"key":"2275_CR28","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/j.jpeds.2006.04.058","volume":"149","author":"LB Vazquez-Cobian","year":"2006","unstructured":"Vazquez-Cobian LB, Flynn T, Lehman TJ (2006) Adalimumab therapy for childhood uveitis. J Pediatr 149:572\u2013575","journal-title":"J Pediatr"},{"key":"2275_CR29","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1002\/acr.20404","volume":"63","author":"G Simonini","year":"2011","unstructured":"Simonini G, Taddio A, Cattalini M, Caputo R, De Libero C, Naviglio S, Bresci C, Lorusso M, Lepore L, Cimaz R (2011) Prevention of flare recurrences in childhood-refractory chronic uveitis: an open-label comparative study of adalimumab versus Infliximab. Arthritis Care Res (Hoboken) 63:612\u2013618","journal-title":"Arthritis Care Res (Hoboken)"},{"key":"2275_CR30","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1136\/ard.2005.044404","volume":"65","author":"ME Weinblatt","year":"2006","unstructured":"Weinblatt ME, Keystone EC, Furst DE, Kavanaugh AF, Chartash EK, Segurado OG (2006) Long term efficacy and safety of adalimumab plus methotrexate in patients with rheumatoid arthritis: ARMADA 4\u00a0year extended study. Ann Rheum Dis 65:753\u2013759","journal-title":"Ann Rheum Dis"},{"key":"2275_CR31","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1016\/S0161-6420(87)80007-6","volume":"94","author":"MD Wolf","year":"1987","unstructured":"Wolf MD, Lichter PR, Ragsdale CG (1987) Prognostic factors in the uveitis of juvenile rheumatoid arthritis. Ophthalmology 94:1242\u20131248","journal-title":"Ophthalmology"},{"key":"2275_CR32","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1136\/bjo.76.2.72","volume":"76","author":"JJ Kanski","year":"1992","unstructured":"Kanski JJ (1992) Lensectomy for complicated cataract in juvenile chronic iridocyclitis. Br J Ophthalmol 76:72\u201375","journal-title":"Br J Ophthalmol"}],"container-title":["Graefe's Archive for Clinical and Experimental Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00417-013-2275-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00417-013-2275-x\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00417-013-2275-x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,28]],"date-time":"2019-05-28T19:48:24Z","timestamp":1559072904000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00417-013-2275-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3,1]]},"references-count":32,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,6]]}},"alternative-id":["2275"],"URL":"https:\/\/doi.org\/10.1007\/s00417-013-2275-x","relation":{},"ISSN":["0721-832X","1435-702X"],"issn-type":[{"value":"0721-832X","type":"print"},{"value":"1435-702X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,3,1]]}}}