{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T15:03:28Z","timestamp":1758121408908},"reference-count":22,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2014,3,14]],"date-time":"2014-03-14T00:00:00Z","timestamp":1394755200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Graefes Arch Clin Exp Ophthalmol"],"DOI":"10.1007\/s00417-014-2603-9","type":"journal-article","created":{"date-parts":[[2014,3,13]],"date-time":"2014-03-13T06:50:06Z","timestamp":1394693406000},"source":"Crossref","is-referenced-by-count":5,"title":["Orthogonal polarization spectral imaging of conjunctival microcirculation"],"prefix":"10.1007","author":[{"given":"Rogier","family":"van Zijderveld","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Can","family":"Ince","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reinier O.","family":"Schlingemann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2014,3,14]]},"reference":[{"issue":"6","key":"2603_CR1","doi-asserted-by":"crossref","first-page":"R601","DOI":"10.1186\/cc3809","volume":"9","author":"EC Boerma","year":"2005","unstructured":"Boerma EC, Mathura KR, van der Voort PH, Spronk PE, Ince C (2005) Quantifying bedside derived imaging of microcirculatory abnormalities in septic patients: a prospective validation study. Crit Care 9(6):R601\u2013R606","journal-title":"Crit Care"},{"key":"2603_CR2","doi-asserted-by":"crossref","first-page":"3999","DOI":"10.1182\/blood.V99.11.3999","volume":"99","author":"AT Cheung","year":"2002","unstructured":"Cheung AT, Chen PC, Larkin EC, Duong PL, Ramanujam S, Tablin F, Wun T (2002) Microvascular abnormalities in sickle cell disease: a computer-assisted intravital microscopy study. Blood 99:3999\u20134005","journal-title":"Blood"},{"key":"2603_CR3","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1097\/00007890-199910150-00005","volume":"68","author":"ATW Cheung","year":"1999","unstructured":"Cheung ATW, Perez RV, Chen PCY (1999) Improvements in diabetic microangiopathy after successful simultaneous pancreas-kidney transplantation: a computer-assisted intravital microscopy study on the conjunctival microcirculation. Transplantation 68:927\u2013932","journal-title":"Transplantation"},{"key":"2603_CR4","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1006\/mvre.2001.2386","volume":"63","author":"ATW Cheung","year":"2002","unstructured":"Cheung ATW, Price AR, Duong PL, Ramanujam S, Gut J, Larkin EC, Chen PCY, Wiltse SL (2002) Microvascular abnormalities in pediatric diabetic patients. Microvasc Res 63:252\u2013258","journal-title":"Microvasc Res"},{"key":"2603_CR5","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.ahj.2003.07.006","volume":"147","author":"D Backer De","year":"2004","unstructured":"De Backer D, Creteur J, Dubois MJ, Sakr Y, Vincent JL (2004) Microvascular alterations in patients with acute severe heart failure and cardiogenic shock. Am Heart J 147:91\u201399","journal-title":"Am Heart J"},{"issue":"5","key":"2603_CR6","doi-asserted-by":"crossref","first-page":"R101","DOI":"10.1186\/cc6118","volume":"11","author":"D Backer De","year":"2007","unstructured":"De Backer D, Hollenberg S, Boerma C, Goedhart P, B\u00fcchele G, Ospina-Tascon G, Dobbe I, Ince C (2007) How to evaluate the microcirculation: report of a round table conference. Crit Care 11(5):R101","journal-title":"Crit Care"},{"key":"2603_CR7","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/0026-2862(79)90025-6","volume":"18","author":"BM Fenton","year":"1979","unstructured":"Fenton BM, Zweifach BW, Worthen DM (1979) Quantitative morphometry of conjunctival microcirculation in diabetes mellitus. Microvasc Res 18:153\u2013166","journal-title":"Microvasc Res"},{"key":"2603_CR8","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1038\/13529","volume":"5","author":"W Groner","year":"1999","unstructured":"Groner W, Winkelman JW, Harris AG, Ince C, Bouma GJ, Messmer K, Nadeau RG (1999) Orthogonal polarization spectral imaging: a new method for study of the microcirculation. Nat Med 5:1209\u20131212","journal-title":"Nat Med"},{"key":"2603_CR9","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1159\/000054079","volume":"37","author":"AG Harris","year":"2000","unstructured":"Harris AG, Sinitsina I, Messmer K (2000) The cytoscan model E-II, a new reflectance microscope for intravital microscopy: comparison with the standard fluorescence method. J Vasc Res 37:469\u2013476","journal-title":"J Vasc Res"},{"key":"2603_CR10","first-page":"137","volume-title":"Microcirculatory technology","author":"M Intaglietta","year":"1986","unstructured":"Intaglietta M, Hammersen F (1986) Measurement of diameter in microvascular studies. In: Baker CH (ed) Microcirculatory technology. Academic Press, Orlando, pp 137\u2013148"},{"issue":"6","key":"2603_CR11","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1515\/bmte.1997.42.6.168","volume":"42","author":"T Klyscz","year":"1997","unstructured":"Klyscz T, J\u00fcnger M, Jung F, Zeintl H (1997) Cap image - a new kind of computer-assisted video image analysis system for dynamic capillary microscopy. Biomed Tech (Berl) 42(6):168\u2013175","journal-title":"Biomed Tech (Berl)"},{"key":"2603_CR12","first-page":"953","volume":"64","author":"N Korber","year":"1986","unstructured":"Korber N, Jung F, Kiesewetter H, Wolf S, Prunte C, Reim M (1986) Microcirculation in the conjunctival capillaries of healthy and hypertensive patients. Klin Wochenschr 64:953\u2013955","journal-title":"Klin Wochenschr"},{"key":"2603_CR13","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1016\/0002-8703(49)90524-4","volume":"38","author":"A Lack","year":"1949","unstructured":"Lack A, Adolph W, Ralston W, Leiby G, Winsor T, Griffith G (1949) Biomicroscopy of conjunctival vessels in hypertension. Am Heart J 38:654\u2013664","journal-title":"Am Heart J"},{"key":"2603_CR14","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1097\/00007890-200105150-00012","volume":"71","author":"S Langer","year":"2001","unstructured":"Langer S, Harris AG, Biberthaler P, von Dobschuetz E, Messmer K (2001) Orthogonal polarization spectral imaging as a tool for the assessment of hepatic microcirculation: a validation study. Transplantation 71:1249\u20131256","journal-title":"Transplantation"},{"key":"2603_CR15","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1016\/S0140-6736(01)06722-8","volume":"358","author":"KR Mathura","year":"2001","unstructured":"Mathura KR, Bouma GJ, Ince C (2001) Abnormal microcirculation in brain tumours during surgery. Lancet 358:1698\u20131699","journal-title":"Lancet"},{"key":"2603_CR16","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1152\/jappl.2001.91.1.74","volume":"91","author":"KR Mathura","year":"2001","unstructured":"Mathura KR, Vollebregt KC, Boer K, de Graaff JC, Ubbink DT, Ince C (2001) Comparison of OPS imaging and conventional capillary microscopy to study the human microcirculation. J Appl Physiol 91:74\u201378","journal-title":"J Appl Physiol"},{"issue":"8","key":"2603_CR17","first-page":"417","volume":"48","author":"A Pransk\u016bnas","year":"2012","unstructured":"Pransk\u016bnas A, Pilvinis V, Dambrauskas \u017d, Rasimavi\u010di\u016bt\u0117 R, Milie\u0161kait\u0117 E, Bubulis A, Veikutis V, Vaitkaitis D, Boerma EC (2012) Microvascular distribution in the ocular conjunctiva and digestive tract in an experimental setting. Med (Kaunas) 48(8):417\u201323","journal-title":"Med (Kaunas)"},{"issue":"12","key":"2603_CR18","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1097\/00003246-198912000-00017","volume":"17","author":"WF Rutherford","year":"1989","unstructured":"Rutherford WF, Panacek EA, Griffith JK, Green JA, Munger M, Bednarczyk E, Miraldi F, Fisher CJ Jr (1989) Prediction of changing cerebral blood flow by use of the conjunctival oxygen tension\/arterial oxygen tension index. Crit Care Med 17(12):1328\u20131332","journal-title":"Crit Care Med"},{"key":"2603_CR19","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1161\/01.HYP.5.6.844","volume":"5","author":"JM Sullivan","year":"1983","unstructured":"Sullivan JM, Prewitt RL, Josephs JA (1983) Attenuation of the microcirculation in young patients with high-output borderline hypertension. Hypertension 5:844\u2013851","journal-title":"Hypertension"},{"key":"2603_CR20","doi-asserted-by":"crossref","first-page":"H2848","DOI":"10.1152\/ajpheart.00117.2003","volume":"285","author":"PM Haaren van","year":"2003","unstructured":"van Haaren PM, van Bavel E, Vink H, Spaan JA (2003) Localization of the permeability barrier to solutes in isolated arteries by confocal microscopy. Am J Physiol Heart Circ Physiol 285:H2848\u2013H2856","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"2603_CR21","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/S0161-6420(81)34970-7","volume":"88","author":"DM Worthen","year":"1981","unstructured":"Worthen DM, Fenton BM, Rosen P, Zweifach BW (1981) Morphometry of diabetic conjunctival blood vessels. Ophthalmology 88:655\u2013657","journal-title":"Ophthalmology"},{"key":"2603_CR22","first-page":"609","volume":"66","author":"C Zeller","year":"1921","unstructured":"Zeller C (1921) Studies on the conjunctival vessels. Klin Monatsbl f Ophthal 66:609","journal-title":"Klin Monatsbl f Ophthal"}],"container-title":["Graefe's Archive for Clinical and Experimental Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00417-014-2603-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00417-014-2603-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00417-014-2603-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,8]],"date-time":"2019-08-08T12:07:07Z","timestamp":1565266027000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00417-014-2603-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3,14]]},"references-count":22,"alternative-id":["2603"],"URL":"https:\/\/doi.org\/10.1007\/s00417-014-2603-9","relation":{},"ISSN":["0721-832X","1435-702X"],"issn-type":[{"value":"0721-832X","type":"print"},{"value":"1435-702X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,3,14]]}}}