{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T07:18:14Z","timestamp":1785568694516,"version":"3.56.0"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2017,1,30]],"date-time":"2017-01-30T00:00:00Z","timestamp":1485734400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["FOR 2240"],"award-info":[{"award-number":["FOR 2240"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["FOR 2240"],"award-info":[{"award-number":["FOR 2240"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000921","name":"European Cooperation in Science and Technology","doi-asserted-by":"publisher","award":["BM1302"],"award-info":[{"award-number":["BM1302"]}],"id":[{"id":"10.13039\/501100000921","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000921","name":"European Cooperation in Science and Technology","doi-asserted-by":"publisher","award":["BM1302"],"award-info":[{"award-number":["BM1302"]}],"id":[{"id":"10.13039\/501100000921","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Graefes Arch Clin Exp Ophthalmol"],"published-print":{"date-parts":[[2017,4]]},"DOI":"10.1007\/s00417-017-3592-2","type":"journal-article","created":{"date-parts":[[2017,1,30]],"date-time":"2017-01-30T11:19:29Z","timestamp":1485775169000},"page":"811-816","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Effect of corneal collagen crosslinking on subsequent deep anterior lamellar keratoplasty (DALK) in keratoconus"],"prefix":"10.1007","volume":"255","author":[{"given":"Friederike","family":"Schaub","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"Enders","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bj\u00f6rn O.","family":"Bachmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ludwig M.","family":"Heindl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claus","family":"Cursiefen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2017,1,30]]},"reference":[{"key":"3592_CR1","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/S0886-3350(01)01181-6","volume":"28","author":"M Anwar","year":"2002","unstructured":"Anwar M, Teichmann KD (2002) Big-bubble technique to bare Descemet\u2019s membrane in anterior lamellar keratoplasty. J Cataract Refract Surg 28:398\u2013403","journal-title":"J Cataract Refract Surg"},{"key":"3592_CR2","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1097\/00003226-200205000-00009","volume":"21","author":"M Anwar","year":"2002","unstructured":"Anwar M, Teichmann KD (2002) Deep lamellar keratoplasty: surgical techniques for anterior lamellar keratoplasty with and without baring of Descemet\u2019s membrane. Cornea 21:374\u2013383","journal-title":"Cornea"},{"key":"3592_CR3","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1136\/bjo.2009.164228","volume":"94","author":"PT Ashwin","year":"2010","unstructured":"Ashwin PT, McDonnell PJ (2010) Collagen cross-linkage: a comprehensive review and directions for future research. Br J Ophthalmol 94:965\u2013970","journal-title":"Br J Ophthalmol"},{"key":"3592_CR4","doi-asserted-by":"crossref","first-page":"5273","DOI":"10.1167\/iovs.13-12576","volume":"54","author":"IM Beshtawi","year":"2013","unstructured":"Beshtawi IM, Akhtar R, Hillarby MC, O\u2019Donnell C, Zhao X, Brahma A, Carley F, Derby B, Radhakrishnan H (2013) Biomechanical properties of human corneas following low- and high-intensity collagen cross-linking determined with scanning acoustic microscopy. Invest Ophthalmol Vis Sci 54:5273\u20135280","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"3592_CR5","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.ophtha.2011.07.057","volume":"119","author":"VM Borderie","year":"2012","unstructured":"Borderie VM, Sandali O, Bullet J, Gaujoux T, Touzeau O, Laroche L (2012) Long-term results of deep anterior lamellar versus penetrating keratoplasty. Ophthalmology 119:249\u2013255","journal-title":"Ophthalmology"},{"key":"3592_CR6","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1111\/cxo.12020","volume":"96","author":"E Chan","year":"2013","unstructured":"Chan E, Snibson GR (2013) Current status of corneal collagen cross-linking for keratoconus: a review. Clin Exp Optom 96:155\u2013164","journal-title":"Clin Exp Optom"},{"key":"3592_CR7","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1007\/s10792-010-9393-9","volume":"30","author":"AW Cohen","year":"2010","unstructured":"Cohen AW, Goins KM, Sutphin JE, Wandling GR, Wagoner MD (2010) Penetrating keratoplasty versus deep anterior lamellar keratoplasty for the treatment of keratoconus. Int Ophthalmol 30:675\u2013681","journal-title":"Int Ophthalmol"},{"key":"3592_CR8","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.jtos.2014.05.002","volume":"12","author":"JA Craig","year":"2014","unstructured":"Craig JA, Mahon J, Yellowlees A, Barata T, Glanville J, Arber M, Mandava L, Powell J, Figueiredo F (2014) Epithelium-off photochemical corneal collagen cross-linkage using riboflavin and ultraviolet a for keratoconus and keratectasia: a systematic review and meta-analysis. Ocul Surf 12:202\u2013214","journal-title":"Ocul Surf"},{"key":"3592_CR9","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1007\/s00347-011-2331-z","volume":"108","author":"C Cursiefen","year":"2011","unstructured":"Cursiefen C, Heindl LM (2011) Perspectives of deep anterior lamellar keratoplasty. Ophthalmologe 108:833\u2013839","journal-title":"Ophthalmologe"},{"key":"3592_CR10","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1007\/s00347-015-0204-6","volume":"113","author":"C Cursiefen","year":"2016","unstructured":"Cursiefen C, Schaub F, Bachmann B (2016) Update: Deep anterior lamellar keratoplasty (DALK) for keratoconus: when, how and why. Ophthalmologe 113:204\u2013212","journal-title":"Ophthalmologe"},{"key":"3592_CR11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.exer.2015.06.015","volume":"138","author":"J Dias","year":"2015","unstructured":"Dias J, Diakonis VF, Lorenzo M, Gonzalez F, Porras K, Douglas S, Avila M, Yoo SH, Ziebarth NM (2015) Corneal stromal elasticity and viscoelasticity assessed by atomic force microscopy after different cross linking protocols. Exp Eye Res 138:1\u20135","journal-title":"Exp Eye Res"},{"key":"3592_CR12","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1097\/ICO.0b013e3181bd9f8c","volume":"29","author":"Y Goldich","year":"2010","unstructured":"Goldich Y, Marcovich AL, Barkana Y, Avni I, Zadok D (2010) Safety of corneal collagen cross-linking with UV-A and riboflavin in progressive keratoconus. Cornea 29:409\u2013411","journal-title":"Cornea"},{"key":"3592_CR13","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.ophtha.2010.05.025","volume":"118","author":"LM Heindl","year":"2011","unstructured":"Heindl LM, Riss S, Bachmann BO, Laaser K, Kruse FE, Cursiefen C (2011) Split cornea transplantation for 2 recipients: a new strategy to reduce corneal tissue cost and shortage. Ophthalmology 118:294\u2013301","journal-title":"Ophthalmology"},{"key":"3592_CR14","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.ajo.2011.03.021","volume":"152","author":"LM Heindl","year":"2011","unstructured":"Heindl LM, Riss S, Laaser K, Bachmann BO, Kruse FE, Cursiefen C (2011) Split cornea transplantation for 2 recipients\u2014review of the first 100 consecutive patients. Am J Ophthalmol 152:523\u2013532","journal-title":"Am J Ophthalmol"},{"key":"3592_CR15","doi-asserted-by":"crossref","first-page":"801","DOI":"10.3928\/1081597X-20131115-02","volume":"29","author":"A Iovieno","year":"2013","unstructured":"Iovieno A, Moramarco A, Coassin M, Baiocchi S, Caporossi A, Fontana L (2013) Big bubble DALK after CXL in keratoconic patients. J Refract Surg 29:801","journal-title":"J Refract Surg"},{"key":"3592_CR16","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1097\/ICO.0b013e31828321dd","volume":"32","author":"A Ivarsen","year":"2013","unstructured":"Ivarsen A, Hjortdal J (2013) Collagen cross-linking for advanced progressive keratoconus. Cornea 32:903\u2013906","journal-title":"Cornea"},{"key":"3592_CR17","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1007\/s10792-009-9334-7","volume":"30","author":"V Jhanji","year":"2010","unstructured":"Jhanji V, Sharma N, Vajpayee RB (2010) Intraoperative perforation of Descemet\u2019s membrane during \u201cbig bubble\u201d deep anterior lamellar keratoplasty. Int Ophthalmol 30:291\u2013295","journal-title":"Int Ophthalmol"},{"key":"3592_CR18","doi-asserted-by":"crossref","first-page":"715","DOI":"10.3109\/02713683.2010.481068","volume":"35","author":"A Kissner","year":"2010","unstructured":"Kissner A, Spoerl E, Jung R, Spekl K, Pillunat LE, Raiskup F (2010) Pharmacological modification of the epithelial permeability by benzalkonium chloride in UVA\/Riboflavin corneal collagen cross-linking. Curr Eye Res 35:715\u2013721","journal-title":"Curr Eye Res"},{"key":"3592_CR19","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1136\/bjo.83.3.327","volume":"83","author":"GR Melles","year":"1999","unstructured":"Melles GR, Lander F, Rietveld FJ, Remeijer L, Beekhuis WH, Binder PS (1999) A new surgical technique for deep stromal, anterior lamellar keratoplasty. Br J Ophthalmol 83:327\u2013333","journal-title":"Br J Ophthalmol"},{"key":"3592_CR20","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/j.survophthal.2015.02.004","volume":"60","author":"JS Parker","year":"2015","unstructured":"Parker JS, van Dijk K, Melles GR (2015) Treatment options for advanced keratoconus: a review. Surv Ophthalmol 60:459\u2013480","journal-title":"Surv Ophthalmol"},{"key":"3592_CR21","first-page":"1","volume":"11","author":"G Pron","year":"2011","unstructured":"Pron G, Ieraci L, Kaulback K (2011) Collagen cross-linking using riboflavin and ultraviolet-a for corneal thinning disorders: an evidence-based analysis. Ont Health Technol Assess Ser 11:1\u201389","journal-title":"Ont Health Technol Assess Ser"},{"key":"3592_CR22","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.ophtha.2010.11.002","volume":"118","author":"WJ Reinhart","year":"2011","unstructured":"Reinhart WJ, Musch DC, Jacobs DS, Lee WB, Kaufman SC, Shtein RM (2011) Deep anterior lamellar keratoplasty as an alternative to penetrating keratoplasty a report by the american academy of ophthalmology. Ophthalmology 118:209\u2013218","journal-title":"Ophthalmology"},{"key":"3592_CR23","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1097\/ICO.0b013e31823f8c85","volume":"31","author":"S Riss","year":"2012","unstructured":"Riss S, Heindl LM, Bachmann BO, Kruse FE, Cursiefen C (2012) Pentacam-based big bubble deep anterior lamellar keratoplasty in patients with keratoconus. Cornea 31:627\u2013632","journal-title":"Cornea"},{"key":"3592_CR24","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1097\/ICO.0b013e31824a226f","volume":"32","author":"S Riss","year":"2013","unstructured":"Riss S, Heindl LM, Bachmann BO, Kruse FE, Cursiefen C (2013) Microbubble incision as a new rescue technique for big-bubble deep anterior lamellar keratoplasty with failed bubble formation. Cornea 32:125\u2013129","journal-title":"Cornea"},{"key":"3592_CR25","doi-asserted-by":"crossref","first-page":"9048","DOI":"10.1167\/iovs.11-7818","volume":"52","author":"S Schumacher","year":"2011","unstructured":"Schumacher S, Oeftiger L, Mrochen M (2011) Equivalence of biomechanical changes induced by rapid and standard corneal cross-linking, using riboflavin and ultraviolet radiation. Invest Ophthalmol Vis Sci 52:9048\u20139052","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"3592_CR26","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1076\/soph.16.3.126.4197","volume":"16","author":"T Senoo","year":"2001","unstructured":"Senoo T (2001) Combined surgery with deep lamellar keratoplasty. Semin Ophthalmol 16:126\u2013136","journal-title":"Semin Ophthalmol"},{"key":"3592_CR27","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1097\/00055735-200008000-00002","volume":"11","author":"J Shimazaki","year":"2000","unstructured":"Shimazaki J (2000) The evolution of lamellar keratoplasty. Curr Opin Ophthalmol 11:217\u2013223","journal-title":"Curr Opin Ophthalmol"},{"key":"3592_CR28","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1080\/02713680490513182","volume":"29","author":"E Spoerl","year":"2004","unstructured":"Spoerl E, Wollensak G, Seiler T (2004) Increased resistance of crosslinked cornea against enzymatic digestion. Curr Eye Res 29:35\u201340","journal-title":"Curr Eye Res"},{"key":"3592_CR29","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1136\/bjo.81.3.184","volume":"81","author":"J Sugita","year":"1997","unstructured":"Sugita J, Kondo J (1997) Deep lamellar keratoplasty with complete removal of pathological stroma for vision improvement. Br J Ophthalmol 81:184\u2013188","journal-title":"Br J Ophthalmol"},{"key":"3592_CR30","doi-asserted-by":"crossref","first-page":"642","DOI":"10.3928\/15428877-20100929-09","volume":"41","author":"M Unal","year":"2010","unstructured":"Unal M, Bilgin B, Yucel I, Akar Y, Apaydin C (2010) Conversion to deep anterior lamellar keratoplasty (DALK): learning curve with big-bubble technique. Ophthalmic Surg Lasers Imaging 41:642\u2013650","journal-title":"Ophthalmic Surg Lasers Imaging"},{"key":"3592_CR31","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/S0002-9394(02)02220-1","volume":"135","author":"G Wollensak","year":"2003","unstructured":"Wollensak G, Spoerl E, Seiler T (2003) Riboflavin\/ultraviolet-a-induced collagen crosslinking for the treatment of keratoconus. Am J Ophthalmol 135:620\u2013627","journal-title":"Am J Ophthalmol"},{"key":"3592_CR32","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.1097\/ICO.0b013e3182a738ba","volume":"32","author":"SN Yeung","year":"2013","unstructured":"Yeung SN, Lichtinger A, Ku JY, Kim P, Low SA, Rootman DS (2013) Intracorneal ring segment explantation after intracorneal ring segment implantation combined with same-day corneal collagen crosslinking in keratoconus. Cornea 32:1617\u20131620","journal-title":"Cornea"}],"container-title":["Graefe's Archive for Clinical and Experimental Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00417-017-3592-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00417-017-3592-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00417-017-3592-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,25]],"date-time":"2017-06-25T05:20:22Z","timestamp":1498368022000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00417-017-3592-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1,30]]},"references-count":32,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,4]]}},"alternative-id":["3592"],"URL":"https:\/\/doi.org\/10.1007\/s00417-017-3592-2","relation":{},"ISSN":["0721-832X","1435-702X"],"issn-type":[{"value":"0721-832X","type":"print"},{"value":"1435-702X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1,30]]}}}