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The scleral spur length was measured using swept-source optical coherence tomography. Receiver operating characteristic (ROC) curves were derived based on the measurements.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>The scleral spur length was significantly shorter in POAG eyes compared with healthy eyes (Method I, 164.91\u2009\u00b1\u200923.36 vs. 197.60\u2009\u00b1\u200925.32\u00a0\u03bcm; Method II, 145.15\u2009\u00b1\u200916.59 vs. 166.95\u2009\u00b1\u200919.31\u00a0\u03bcm; Method III, 162.33\u2009\u00b1\u200922.83 vs. 185.12\u2009\u00b1\u200923.58\u00a0\u03bcm, respectively; all <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001). The areas under ROC curves were 0.841 (Method I), 0.810 (Method II), and 0.753 (Method III) for the scleral spur length. Moreover, Schlemm\u2019s canal area was significantly associated with the scleral spur length (Method I) in both POAG (\u03b2\u2009=\u20090.027; <jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001) and healthy (\u03b2\u2009=\u20090.016; <jats:italic>p<\/jats:italic>\u2009=\u20090.009) groups.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>The scleral spur length had a good discriminating capability between POAG and healthy eyes, and it could be a novel biomarker for POAG evaluation clinically.<\/jats:p>\n<\/jats:sec>","DOI":"10.1007\/s00417-020-04637-4","type":"journal-article","created":{"date-parts":[[2020,3,7]],"date-time":"2020-03-07T07:02:51Z","timestamp":1583564571000},"page":"1253-1260","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Diagnostic power of scleral spur length in primary open-angle glaucoma"],"prefix":"10.1007","volume":"258","author":[{"given":"Mu","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaoxia","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoqin","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2020,3,7]]},"reference":[{"key":"4637_CR1","doi-asserted-by":"publisher","first-page":"2081","DOI":"10.1016\/j.ophtha.2014.05.013","volume":"121","author":"YC Tham","year":"2014","unstructured":"Tham YC, Li X, Wong TY, Quigley HA, Aung T, Cheng CY (2014) Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis. 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