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Xu, X. Wang, and Y. Zhang report no conflicts of interest. S. R. Sadda receives research funding from Allergan, Carl Zeiss Meditec, Genentech, Optos and Topcon. S. R. Sadda is a consultant for Allergan, Centervue, Genentech, Heidelberg, Iconic, Novartis, Optos, Oxurion.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"This study followed the tenets of the Declaration of Helsinki and was approved by the Institutional Review Boards at the University of Alabama at Birmingham (UAB IRB-141024002 & UAB IRB-100928002) and the University of California \u2013 Los Angeles (UCLA IRB-19-000011).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval"}},{"value":"Written informed consent for participating in the study was obtained from participants after the nature and possible consequences of the study were explained.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Written informed consent for publication was obtained from all participants.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}]}}