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Patients with intra- or postoperative complications as well as pre-existing risk factors for ME were excluded. Macular spectral-domain optical coherence tomography (SD-OCT) and best spectacle-corrected visual acuity (BSCVA) measurements were performed before, 1\u00a0week, 1\u00a0month, and 6\u00a0months after surgery. Retinal thickness (RT) was analyzed in the central foveal 1\u00a0mm (CSF), parafoveal 3\u00a0mm and 6\u00a0mm subfield.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Eight eyes (7.5%) developed DMEK-ME 1\u00a0month after surgery. Six DMEK-ME eyes (75%) were rebubbled, compared with 31.3% (31 of 99; <jats:italic>P<\/jats:italic>\u00a0=\u20090.02) of the non DMEK-ME eyes. DMEK-ME eyes had a significantly thicker CSF 1\u00a0month after surgery (432.0\u2009\u00b1\u200997.6\u00a0\u03bcm) compared with non-DMEK-ME eyes (283.7\u2009\u00b1\u200922.2\u00a0\u03bcm; <jats:italic>P<\/jats:italic>\u00a0=\u20090.01). The other subfields and time points showed no significant RT changes. DMEK-ME significantly impaired BSCVA (0.38\u2009\u00b1\u20090.92 logMAR) only 1\u00a0month after surgery in comparison to the non DMEK-ME eyes (0.23\u2009\u00b1\u20090.87 logMAR, <jats:italic>P<\/jats:italic>\u00a0=\u20090.015).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Excluding systemic and surgery-related risk factors, rebubbling increases the risk of DMEK-ME. Performing a CSF scan 1\u00a0month after surgery, particularly in rebubbled eyes, efficiently detects DMEK-ME and allows the prompt initiation of treatment, e.g., topical corticosteroid and non-steroidal (NSAID) eye drops.\n<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00417-021-05203-2","type":"journal-article","created":{"date-parts":[[2021,5,11]],"date-time":"2021-05-11T17:03:47Z","timestamp":1620752627000},"page":"2731-2741","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Effects of uncomplicated Descemet membrane endothelial keratoplasty on the central retinal thickness"],"prefix":"10.1007","volume":"259","author":[{"given":"Tibor","family":"Lohmann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabine","family":"Baumgarten","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niklas","family":"Plange","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Walter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0573-2599","authenticated-orcid":false,"given":"Matthias","family":"Fuest","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,5,11]]},"reference":[{"issue":"2","key":"5203_CR1","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1016\/j.ophtha.2017.08.015","volume":"125","author":"SX Deng","year":"2018","unstructured":"Deng SX, Lee WB, Hammersmith KM, Kuo AN, Li JY, Shen JF, Weikert MP, Shtein RM (2018) Descemet membrane endothelial Keratoplasty: safety and outcomes: a report by the American Academy of ophthalmology. 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