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All eyes underwent a complete ophthalmic examination (axial length, macular imaging with swept-source OCT, and MAIA microperimetry). Macular thicknesses, ganglion cell complex (GCC) thicknesses, and central retinal sensitivity were compared between groups, and the relationships between the OCT and microperimetry parameters were evaluated.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Macular thickness was similar in both groups (242.17\u2009\u00b1\u200935.0 in the DM2 group vs 260.64\u2009\u00b1\u200973.9 in the control group). There was a diminution in the parafoveal area thickness in the DM2 group in the GCC complex. Retinal sensitivity was reduced in all sectors in the DM2 group. The central global value was 24.01\u2009\u00b1\u20095.7 in the DM2 group and 27.31\u2009\u00b1\u20092.7 in the control group (p\u2009&lt;\u20090.001). Macular integrity was 80.89\u2009\u00b1\u200926.4 vs 64.70\u2009\u00b1\u200928.3 (p\u2009&lt;\u20090.001) and total mean threshold was 23.90\u2009\u00b1\u20094.9 vs 26.48\u2009\u00b1\u20092.6 (p\u2009&lt;\u20090.001) in the DM2 and control group, respectively. Moderate correlations were detected between the central sector of MAIA microperimetry and retina total central thickness (\u2212\u20090.347; p\u2009=\u20090.0035). Age, visual acuity, and hemoglobin A1c levels also correlated with retinal sensitivity.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Macular GCC thickness and central retinal sensitivity were reduced in patients with moderate DR without DME, suggesting the presence of macular neurodegeneration.\n<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00417-021-05277-y","type":"journal-article","created":{"date-parts":[[2021,7,15]],"date-time":"2021-07-15T04:03:16Z","timestamp":1626321796000},"page":"3625-3635","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Structural and functional findings in patients with moderate diabetic retinopathy"],"prefix":"10.1007","volume":"259","author":[{"given":"A.","family":"Boned-Murillo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. 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