{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T19:53:45Z","timestamp":1789588425804,"version":"build-2803163510"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2021,9,16]],"date-time":"2021-09-16T00:00:00Z","timestamp":1631750400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,9,16]],"date-time":"2021-09-16T00:00:00Z","timestamp":1631750400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"Johann Wolfgang Goethe-Universit\u00e4t, Frankfurt am Main"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Graefes Arch Clin Exp Ophthalmol"],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n                <jats:title>Purpose<\/jats:title>\n                <jats:p>To investigate short-term (3\u00a0months follow-up) changes in visual quality following Descemet membrane endothelial keratoplasty (DMEK) for Fuchs endothelial dystrophy (FED).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>In this prospective institutional case series, 51 patients that underwent DMEK for FED were included. Assessment included the Quality of Vision (QoV) questionnaire preoperatively, at 1\u00a0month, and 3\u00a0months after surgery. Secondary outcome measures were anterior segment parameters acquired by Scheimpflug imaging, corrected distance visual acuity (CDVA), and endothelial cell density (ECD).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Glare, hazy vision, blurred vision, and daily fluctuation in vision were the symptoms mostly reported preoperatively. All symptoms demonstrated a significant reduction of item scores for severity, frequency, and bothersome in the course after DMEK (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.01). Glare and fluctuation in vision remained to some extent during the follow-up period (median score\u2009=\u20091). Preoperatively, corneal densitometry correlated moderately to weakly with severity of hazy vision (<jats:italic>r<\/jats:italic><jats:sub>s<\/jats:sub>\u2009=\u20090.39; <jats:italic>P<\/jats:italic>\u2009=\u20090.03) and frequency (<jats:italic>r<\/jats:italic><jats:sub>s<\/jats:sub>\u2009=\u20090.26; <jats:italic>P<\/jats:italic>\u2009=\u20090.02) as well as severity (<jats:italic>r<\/jats:italic><jats:sub>s<\/jats:sub>\u2009=\u20090.27; <jats:italic>P<\/jats:italic>\u2009=\u20090.03) of blurry vision. CDVA and central corneal thickness (CCT) did not correlate with visual complains.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>Following DMEK for FED, patient-reported visual symptoms assessed by the QoV questionnaire represent a useful tool providing valuable information on the impact of DMEK on visual quality that cannot be directly estimated by morphological parameters and visual acuity only.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00417-021-05334-6","type":"journal-article","created":{"date-parts":[[2021,9,16]],"date-time":"2021-09-16T12:02:48Z","timestamp":1631793768000},"page":"521-528","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Impact of DMEK on visual quality in patients with Fuchs\u2019 endothelial dystrophy"],"prefix":"10.1007","volume":"260","author":[{"given":"Vanessa","family":"Ademmer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bishr","family":"Agha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehdi","family":"Shajari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6933-9585","authenticated-orcid":false,"given":"Thomas","family":"Kohnen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ingo","family":"Schmack","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,9,16]]},"reference":[{"issue":"2","key":"5334_CR1","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1016\/j.ophtha.2017.08.015","volume":"125","author":"SX Deng","year":"2018","unstructured":"Deng SX, Lee WB, Hammersmith KM et al (2018) Descemet membrane endothelial keratoplasty: safety and outcomes: a report by the American Academy of Ophthalmology. 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Consultant for Allergan, Bausch & Lomb, Domp\u00e9, Geuder, LensGen, Merck, Rayner, Santen, Staar, Thea, Tear Lab, Thieme, Uni-Med Verlag, Med Update, and Ziemer. Research for Hoya. MS: consultant for Oculus, Staar, and Zeiss. The other authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}