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A hundred and eight volunteers aged 20 to 79, including 68 MGD patients and 40 normal subjects, were recruited. Using OCT and keratograph to measure the LLMT from the posterior lash line to anterior edge or outer edge of the tear meniscus was separately performed two times by the same person.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The mean age of normal and MGD subjects was 50.5\u2009\u00b1\u200914.2\u00a0years and 55.8\u2009\u00b1\u200915.5\u00a0years, respectively. The LLMT with OCT and keratograph in MGD patients was significantly greater than that in normal subjects (1.06\u2009\u00b1\u20090.27 and 1.03\u2009\u00b1\u20090.25\u00a0mm vs. 0.90\u2009\u00b1\u20090.20 and 0.86\u2009\u00b1\u20090.16\u00a0mm, respectively). In both normal and MGD subjects, the tear meniscus height and LLMT with OCT were both greater than that with keratograph (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.05), and intraclass correlation coefficient (ICC) demonstrated a good agreement in the LLMT measurements between two devices (ICC\u2009=\u20090.83 and 0.79, respectively). Additionally, the LLMT in MGD patients was appeared to be positively correlated with meiboscore (<jats:italic>r<\/jats:italic><jats:sub>s<\/jats:sub>\u2009=\u20090.37, <jats:italic>P<\/jats:italic>\u2009=\u20090.002).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusions<\/jats:title>\n                <jats:p>The OCT and keratograph were two reliable tools in the LLMT measurements, which may have potential applications for diagnosis and evaluation of MGD. Furthermore, we found that the LLMT measured by OCT was greater than that measured by keratograph.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00417-023-05990-w","type":"journal-article","created":{"date-parts":[[2023,3,2]],"date-time":"2023-03-02T04:36:12Z","timestamp":1677731772000},"page":"2327-2334","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Application of optical coherence tomography and keratograph in the measurements of lower lid margin thickness"],"prefix":"10.1007","volume":"261","author":[{"given":"Da-Hu","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian-Cen","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao-Jun","family":"Hao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yin-Jian","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4395-2004","authenticated-orcid":false,"given":"Xin-Quan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,3,2]]},"reference":[{"key":"5990_CR1","doi-asserted-by":"publisher","first-page":"1917","DOI":"10.1167\/iovs.10-6997","volume":"52","author":"KK Nichols","year":"2011","unstructured":"Nichols KK (2011) The International Workshop on Meibomian Gland Dysfunction: Introduction. 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