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OCTA was done before patients\u2019 treatment with optical correction with or without patching and was repeated after successful amblyopia treatment. Outcomes included superficial, deep, and choriocapillaris vessel density (VD) and superficial and deep FAZ areas.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The study included 13 males (40.6%) and 19 females (59.4%), and the mean age was 9.52\u2009\u00b1\u20091.33\u00a0years. Fifty-three percent (53%) of patients needed only optical correction, and the remaining 47% needed additional patching therapy. After successful treatment, there was a significant improvement in amblyopic eyes in best-corrected visual acuity (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), with higher VD values in superficial capillary plexuses (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), deep capillary plexuses (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.001), and foveal choriocapillaris (<jats:italic>p<\/jats:italic>\u2009=\u20090.030). In the glasses with patching subgroup, the difference between pre-treatment and post-treatment parameters revealed a significant improvement in vessel density in superficial retinal plexuses (foveal and parafoveal; <jats:italic>p<\/jats:italic> values 0.023 and\u2009&lt;\u20090.001, respectively) and deep retinal plexuses (whole image, foveal, and parafoveal; <jats:italic>p<\/jats:italic> values 0.003,\u2009&lt;\u20090.001, and 0.002, respectively). While amblyopic eyes treated with glasses alone had a significantly greater difference in choriocapillaris foveal VD (<jats:italic>p<\/jats:italic> value\u2009=\u20090.022).<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>After effective amblyopia treatment, amblyopic eyes exhibited improved best-corrected visual acuity and better macular perfusion along the superficial, deep vascular density, and choriocapillaris foveal VD.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Clinical trial registration<\/jats:title>\n                <jats:p>CinicalTrials.gov Identifier: NCT05223153.\n<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s00417-023-06055-8","type":"journal-article","created":{"date-parts":[[2023,4,13]],"date-time":"2023-04-13T11:04:48Z","timestamp":1681383888000},"page":"2689-2699","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Assessment of macular microvascular changes in children following treatment of anisometropic myopic amblyopia using optical coherence tomography angiography"],"prefix":"10.1007","volume":"261","author":[{"given":"Heba Radi","family":"AttaAllah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2435-7701","authenticated-orcid":false,"given":"Sahar Torky Abdelrazik","family":"Abdelaziz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asmaa Anwar Mohamed","family":"Mohamed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed Farag Khalil","family":"Ibrahiem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,4,13]]},"reference":[{"issue":"1","key":"6055_CR1","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.ophtha.2017.10.008","volume":"125","author":"DK Wallace","year":"2018","unstructured":"Wallace DK, Repka MX, Lee KA et al (2018) Amblyopia preferred practice pattern. 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