{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T04:54:24Z","timestamp":1774414464743,"version":"3.50.1"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"10","license":[{"start":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T00:00:00Z","timestamp":1684368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T00:00:00Z","timestamp":1684368000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Graefes Arch Clin Exp Ophthalmol"],"published-print":{"date-parts":[[2023,10]]},"DOI":"10.1007\/s00417-023-06113-1","type":"journal-article","created":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T11:03:03Z","timestamp":1684407783000},"page":"2953-2959","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Topical antibiotic prophylaxis before intravitreal injections: a pilot study"],"prefix":"10.1007","volume":"261","author":[{"given":"Edoardo","family":"Trovato Battagliola","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodolfo Javier","family":"Riveros Cabral","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregorio","family":"Manco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianluca","family":"Puggioni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudio","family":"Brancato","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pietro","family":"Mangiantini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Floriana","family":"Testa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariaelena","family":"Malvasi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giammarco","family":"Raponi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Turchetti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernanda","family":"Pacella","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5431-6399","authenticated-orcid":false,"given":"Elena","family":"Pacella","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2023,5,18]]},"reference":[{"issue":"6","key":"6113_CR1","first-page":"e413","volume":"163","author":"E Pacella","year":"2012","unstructured":"Pacella E, Pacella F, La Torre G, Impallara D, Malarska K, Brillante C, Turchetti P, De Giusti M (2012) Testing the effectiveness of intravitreal ranibizumab during 12 months of follow-up in venous occlusion treatment. Clin Ter 163(6):e413\u2013e422","journal-title":"Clin Ter"},{"issue":"1","key":"6113_CR2","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1097\/IAE.0b013e31829f74b0","volume":"34","author":"H Casparis","year":"2014","unstructured":"Casparis H, Wolfensberger TJ, Becker M, Eich G, Graf N, Ambresin A, Mantel I, Michels S (2014) Incidence of presumed endophthalmitis after intravitreal injection performed in the operating room: a retrospective multicenter study. (Retina Philadelphia, Pa) 34(1):12\u201317. https:\/\/doi.org\/10.1097\/IAE.0b013e31829f74b0","journal-title":"(Retina Philadelphia, Pa)"},{"issue":"12","key":"6113_CR3","doi-asserted-by":"publisher","first-page":"2341","DOI":"10.1097\/IAE.0000000000001488","volume":"37","author":"FJ Freiberg","year":"2017","unstructured":"Freiberg FJ, Brynskov T, Munk MR, S\u00f8rensen TL, Wolf S, Wirth MA, Becker M, Michels S (2017) Low endophthalmitis rates after intravitreal anti-vascular endothelial growth factor injections in an operation room: a retrospective multicenter study. Retina (Philadelphia, Pa) 37(12):2341\u20132346. https:\/\/doi.org\/10.1097\/IAE.0000000000001488","journal-title":"Retina (Philadelphia, Pa)"},{"issue":"1","key":"6113_CR4","doi-asserted-by":"publisher","first-page":"282","DOI":"10.1186\/s13256-016-1077-2","volume":"10","author":"F Pacella","year":"2016","unstructured":"Pacella F, Agostinelli E, Carlesimo SC, Nebbioso M, Secondi R, Forastiere M, Pacella E (2016) Management of anterior chamber dislocation of a dexamethasone intravitreal implant: a case report. J Med Case Reports 10(1):282. https:\/\/doi.org\/10.1186\/s13256-016-1077-2","journal-title":"J Med Case Reports"},{"key":"6113_CR5","doi-asserted-by":"publisher","unstructured":"Pacella F, Pacella E, Trovato Battagliola E, Malvasi M, Scalinci SZ, Turchetti P, Salducci M, Lucchino L, & Arrico L (2021). Efficacy and safety of intravitreal fluocinolone acetonide microimplant (ILUVIEN\u00ae) in patients with chronic diabetic macular edema: 1\u2009year follow-up.\u00a0European journal of ophthalmology, 11206721211020203. Advance online publication. https:\/\/doi.org\/10.1177\/11206721211020203","DOI":"10.1177\/11206721211020203"},{"key":"6113_CR6","doi-asserted-by":"publisher","unstructured":"Morioka M, Takamura Y, Nagai K, Yoshida S, Mori J, Takeuchi M, Sawada T, Sone K, Fukuyama H, Kusuhara S, Yasukawa T, Murakami T, Tabuchi H, Nagasato D, Hirano T, Ueda T, Jujo T, Sasajima H, Mitamura Y, Ishikawa K, \u2026 Inatani M (2020). Incidence of endophthalmitis after intravitreal injection of an anti-VEGF agent with or without topical antibiotics.\u00a0Sci Rep,\u00a010(1), 22122. https:\/\/doi.org\/10.1038\/s41598-020-79377-w","DOI":"10.1038\/s41598-020-79377-w"},{"issue":"2","key":"6113_CR7","doi-asserted-by":"publisher","first-page":"600","DOI":"10.1177\/1120672120902028","volume":"31","author":"S Torres-Costa","year":"2021","unstructured":"Torres-Costa S, Ramos D, Brand\u00e3o E, Carneiro \u00c2, Rosas V, Rocha-Sousa A, Falc\u00e3o-Reis F, Falc\u00e3o M (2021) Incidence of endophthalmitis after intravitreal injection with and without topical antibiotic prophylaxis. Eur J Ophthalmol 31(2):600\u2013606. https:\/\/doi.org\/10.1177\/1120672120902028","journal-title":"Eur J Ophthalmol"},{"key":"6113_CR8","doi-asserted-by":"publisher","first-page":"3611","DOI":"10.2147\/OPTH.S265691","volume":"14","author":"E Pacella","year":"2020","unstructured":"Pacella E, Loffredo L, Malvasi M, TrovatoBattagliola E, Messineo D, Pacella F, Arrico L (2020) Effects of repeated intravitreal injections of dexamethasone implants on intraocular pressure: a 4-year study. Clinical ophthalmology (Auckland, NZ) 14:3611\u20133617. https:\/\/doi.org\/10.2147\/OPTH.S265691","journal-title":"Clinical ophthalmology (Auckland, NZ)"},{"issue":"5","key":"6113_CR9","doi-asserted-by":"publisher","first-page":"435","DOI":"10.1111\/aos.13417","volume":"96","author":"AP Hunyor","year":"2018","unstructured":"Hunyor AP, Merani R, Darbar A, Korobelnik JF, Lanzetta P, Okada AA (2018) Topical antibiotics and intravitreal injections. Acta Ophthalmol 96(5):435\u2013441. https:\/\/doi.org\/10.1111\/aos.13417","journal-title":"Acta Ophthalmol"},{"issue":"5","key":"6113_CR10","doi-asserted-by":"publisher","first-page":"396","DOI":"10.1007\/s10384-019-00684-5","volume":"63","author":"K Tanaka","year":"2019","unstructured":"Tanaka K, Shimada H, Mori R, Nakashizuka H, Hattori T, Okubo Y (2019) No increase in incidence of post-intravitreal injection endophthalmitis without topical antibiotics: a prospective study. Jpn J Ophthalmol 63(5):396\u2013401. https:\/\/doi.org\/10.1007\/s10384-019-00684-5","journal-title":"Jpn J Ophthalmol"},{"issue":"4","key":"6113_CR11","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1016\/j.jcjo.2020.01.015","volume":"55","author":"PP Storey","year":"2020","unstructured":"Storey PP, Patel D, Garg S (2020) Endophthalmitis following intravitreal injection of anti-vascular endothelial growth factor agents Canadian journal of ophthalmology. Journal canadien d\u2019ophtalmologie 55(4):286\u2013292. https:\/\/doi.org\/10.1016\/j.jcjo.2020.01.015","journal-title":"Journal canadien d'ophtalmologie"},{"issue":"12","key":"6113_CR12","doi-asserted-by":"publisher","first-page":"1633","DOI":"10.1007\/s00417-006-0360-0","volume":"244","author":"T Puustj\u00e4rvi","year":"2006","unstructured":"Puustj\u00e4rvi T, Ter\u00e4svirta M, Nurmenniemi P, Lokkila J, Uusitalo H (2006) Penetration of topically applied levofloxacin 0.5% and ofloxacin 0.3% into the vitreous of the non-inflamed human eye. Graefes Arch Clin Exp Ophthalmol= Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 244(12):1633\u20131637","journal-title":"Graefes Arch Clin Exp Ophthalmol= Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie"},{"issue":"3","key":"6113_CR13","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1016\/s0886-3350(02)01538-9","volume":"29","author":"IS Yalvac","year":"2003","unstructured":"Yalvac IS, Basci NE, Bozkurt A, Duman S (2003) Penetration of topically applied ciprofloxacin and ofloxacin into the aqueous humor and vitreous. J Cataract Refract Surg 29(3):487\u2013491. https:\/\/doi.org\/10.1016\/s0886-3350(02)01538-9","journal-title":"J Cataract Refract Surg"},{"issue":"3","key":"6113_CR14","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1177\/112067210701700316","volume":"17","author":"H Sakamoto","year":"2007","unstructured":"Sakamoto H, Sakamoto M, Hata Y, Kubota T, Ishibashi T (2007) Aqueous and vitreous penetration of levofloxacin after topical and\/or oral administration. Eur J Ophthalmol 17(3):372\u2013376. https:\/\/doi.org\/10.1177\/112067210701700316","journal-title":"Eur J Ophthalmol"},{"issue":"6","key":"6113_CR15","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1097\/00006982-199806000-00005","volume":"18","author":"O Cekic","year":"1998","unstructured":"Cekic O, Batman C, Yasar U, Basci NE, Bozkurt A, Kayaalp SO (1998) Penetration of ofloxacin in human aqueous and vitreous humors following oral and topical administration. Retina (Philadelphia, Pa) 18(6):521\u2013525. https:\/\/doi.org\/10.1097\/00006982-199806000-00005","journal-title":"Retina (Philadelphia, Pa)"},{"issue":"2","key":"6113_CR16","doi-asserted-by":"publisher","first-page":"e121","DOI":"10.7417\/CT.2013.1543","volume":"164","author":"E Pacella","year":"2013","unstructured":"Pacella E, La Torre G, Impallara D, Malarska K, Turchetti P, Brillante C, Smaldone G, De Paolis G, Muscella R, Pacella F (2013) Efficacy and safety of the intravitreal treatment of diabetic macular edema with pegaptanib: a 12-month follow-up. Clin Ter 164(2):e121\u2013e126. https:\/\/doi.org\/10.7417\/CT.2013.1543","journal-title":"Clin Ter"},{"issue":"4","key":"6113_CR17","doi-asserted-by":"publisher","first-page":"265","DOI":"10.3341\/kjo.2019.0144","volume":"34","author":"H Kaldirim","year":"2020","unstructured":"Kaldirim H, Yazgan S, Kirgiz A, Ozdemir B, Yilmaz A (2020) Effect of topical antibiotic prophylaxis on conjunctival flora and antibiotic resistance following intravitreal injections in patients with type 2 diabetes. Korean J Pphthalmol\u202f: KJO 34(4):265\u2013273. https:\/\/doi.org\/10.3341\/kjo.2019.0144","journal-title":"Korean J Pphthalmol : KJO"},{"issue":"2","key":"6113_CR18","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1007\/s00417-015-3035-x","volume":"254","author":"P Storey","year":"2016","unstructured":"Storey P, Dollin M, Rayess N, Pitcher J, Reddy S, Vander J, Hsu J, Garg S, & Post-Injection Endophthalmitis Study Team (2016) The effect of prophylactic topical antibiotics on bacterial resistance patterns in endophthalmitis following intravitreal injection. Graefe\u2019s Arch Clin Exp Ophthalmol Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 254(2):235\u2013242. https:\/\/doi.org\/10.1007\/s00417-015-3035-x","journal-title":"Graefe's Arch Clin Exp Ophthalmol Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie"},{"issue":"4","key":"6113_CR19","doi-asserted-by":"publisher","first-page":"e266","DOI":"10.7417\/T.2017.2018","volume":"168","author":"F Pacella","year":"2017","unstructured":"Pacella F, Collini S, Angelucci F, Agostinelli E, Guzzo AS, Cerza C, Pacella E (2017) Infections in hospital departments What is hospital responsibility? La Clinica terapeutica 168(4):e266\u2013e270. https:\/\/doi.org\/10.7417\/T.2017.2018","journal-title":"La Clinica terapeutica"},{"issue":"Suppl 1","key":"6113_CR20","doi-asserted-by":"publisher","first-page":"S17","DOI":"10.1093\/cid\/ciaa1581","volume":"72","author":"RE Nelson","year":"2021","unstructured":"Nelson RE, Hatfield KM, Wolford H, Samore MH, Scott RD, Reddy SC, Olubajo B, Paul P, Jernigan JA, Baggs J (2021) National estimates of healthcare costs associated with multidrug-resistant bacterial infections among hospitalized patients in the United States. Clin Infect Dis\u202f: Off Publ Infect Dis Soc Am 72(Suppl 1):S17\u2013S26. https:\/\/doi.org\/10.1093\/cid\/ciaa1581","journal-title":"Clin Infect Dis : Off Publ Infect Dis Soc Am"},{"issue":"24","key":"6113_CR21","doi-asserted-by":"publisher","first-page":"9012","DOI":"10.26355\/eurrev_201812_16672","volume":"22","author":"S De Sio","year":"2018","unstructured":"De Sio S, Letizia C, Petramala L, Saracino V, Cedrone F, Sanguigni P, Buomprisco G, Perri R, TrovatoBattagliola E, Mannocci A, La Torre G (2018) Work-related stress and cortisol levels: is there an association? Results of an observational study. Eur Rev Med Pharmacol Sci 22(24):9012\u20139017. https:\/\/doi.org\/10.26355\/eurrev_201812_16672","journal-title":"Eur Rev Med Pharmacol Sci"},{"issue":"9","key":"6113_CR22","doi-asserted-by":"publisher","first-page":"e00682","DOI":"10.1128\/AAC.00682-20","volume":"64","author":"D Lepelletier","year":"2020","unstructured":"Lepelletier D, Maillard JY, Pozzetto B, Simon A (2020) Povidone iodine: properties, mechanisms of action, and role in infection control and Staphylococcus aureus Decolonization. Antimicrob Agents Chemother 64(9):e00682-e720. https:\/\/doi.org\/10.1128\/AAC.00682-20","journal-title":"Antimicrob Agents Chemother"},{"key":"6113_CR23","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.atherosclerosissup.2019.08.031","volume":"40","author":"C Stefanutti","year":"2019","unstructured":"Stefanutti C, Mesce D, Pacella F, Di Giacomo S, Turchetti P, Forastiere M, TrovatoBattagliola E, La Torre G, Smaldone G, Pacella E (2019) Optical coherence tomography of retinal and choroidal layers in patients with familial hypercholesterolaemia treated with lipoprotein apheresis. Atheroscler Suppl 40:49\u201354. https:\/\/doi.org\/10.1016\/j.atherosclerosissup.2019.08.031","journal-title":"Atheroscler Suppl"},{"key":"6113_CR24","doi-asserted-by":"publisher","unstructured":"Avery RL, Bakri SJ, Blumenkranz MS, Brucker AJ, Cunningham ET Jr, D\u02bcAmico DJ, Dugel PU, Flynn HW Jr, Freund KB, Haller JA, Jumper JM, Liebmann JM, McCannel CA, Mieler WF, Ta CN, & Williams GA (2014). Intravitreal injection technique and monitoring: updated guidelines of an expert panel.\u00a0Retina (Philadelphia, Pa.),\u00a034 Suppl 12, S1\u2013S18.\u00a0https:\/\/doi.org\/10.1097\/IAE.0000000000000399","DOI":"10.1097\/IAE.0000000000000399"},{"issue":"10","key":"6113_CR25","doi-asserted-by":"publisher","first-page":"2032","DOI":"10.1097\/IAE.0b013e31820f4b4f","volume":"31","author":"SS Bhatt","year":"2011","unstructured":"Bhatt SS, Stepien KE, Joshi K (2011) Prophylactic antibiotic use after intravitreal injection: effect on endophthalmitis rate. Retina (Philadelphia, Pa) 31(10):2032\u20132036. https:\/\/doi.org\/10.1097\/IAE.0b013e31820f4b4f","journal-title":"Retina (Philadelphia, Pa)"},{"issue":"9","key":"6113_CR26","doi-asserted-by":"publisher","first-page":"1000","DOI":"10.1080\/02713683.2019.1610179","volume":"44","author":"S Abdolrahimzadeh","year":"2019","unstructured":"Abdolrahimzadeh S, Gharbiya M, Formisano M, Bertini F, Cerini A, Pacella E (2019) Anti-vascular endothelial growth factor intravitreal therapy and macular ganglion cell layer thickness in patients with neovascular age-related macular degeneration. Curr Eye Res 44(9):1000\u20131005. https:\/\/doi.org\/10.1080\/02713683.2019.1610179","journal-title":"Curr Eye Res"},{"issue":"5","key":"6113_CR27","doi-asserted-by":"publisher","first-page":"1283","DOI":"10.12669\/pjms.345.14817","volume":"34","author":"A Asghar","year":"2018","unstructured":"Asghar A, Ellhai I, Obaid N, Sughra U (2018) Role of topical antibiotics in prophylaxis against endophthalmitis following intravitreal antibiotics. Pakistan J Med Sci 34(5):1283\u20131287. https:\/\/doi.org\/10.12669\/pjms.345.14817","journal-title":"Pakistan J Med Sci"},{"issue":"8","key":"6113_CR28","doi-asserted-by":"publisher","first-page":"1609","DOI":"10.1016\/j.ophtha.2012.02.014","volume":"119","author":"CS Cheung","year":"2012","unstructured":"Cheung CS, Wong AW, Lui A, Kertes PJ, Devenyi RG, Lam WC (2012) Incidence of endophthalmitis and use of antibiotic prophylaxis after intravitreal injections. Ophthalmology 119(8):1609\u20131614. https:\/\/doi.org\/10.1016\/j.ophtha.2012.02.014","journal-title":"Ophthalmology"},{"issue":"4","key":"6113_CR29","doi-asserted-by":"publisher","first-page":"408","DOI":"10.1016\/j.survophthal.2019.12.005","volume":"65","author":"SN Patel","year":"2020","unstructured":"Patel SN, Gangaputra S, Sternberg P Jr, Kim SJ (2020) Prophylaxis measures for postinjection endophthalmitis. Surv Ophthalmol 65(4):408\u2013420. https:\/\/doi.org\/10.1016\/j.survophthal.2019.12.005","journal-title":"Surv Ophthalmol"},{"key":"6113_CR30","doi-asserted-by":"publisher","unstructured":"Storey PP, Tauqeer Z, Yonekawa Y, Todorich B, Wolfe JD, Shah SP, Shah AR, Koto T, Abbey AM, Morizane Y, Sharma P, Wood EH, Morizane-Hosokawa M, Pendri P, Pancholy M, Harkey S, Jeng-Miller KW, Obeid A, Borkar DS, Chen E, \u2026 Post-Injection Endophthalmitis (PIE) Study Group (2019). The impact of prefilled syringes on endophthalmitis following intravitreal injection of ranibizumab.\u00a0Am J Ophthalmol,\u00a0199, 200\u2013208. https:\/\/doi.org\/10.1016\/j.ajo.2018.11.023","DOI":"10.1016\/j.ajo.2018.11.023"},{"issue":"12","key":"6113_CR31","doi-asserted-by":"publisher","first-page":"2588","DOI":"10.1016\/j.ophtha.2016.08.022","volume":"123","author":"R Merani","year":"2016","unstructured":"Merani R, McPherson ZE, Luckie AP, Gilhotra JS, Runciman J, Durkin S, Muecke J, Donaldson M, Aralar A, Rao A, Davies PE (2016) Aqueous chlorhexidine for intravitreal injection antisepsis: a case series and review of the literature. Ophthalmology 123(12):2588\u20132594. https:\/\/doi.org\/10.1016\/j.ophtha.2016.08.022","journal-title":"Ophthalmology"},{"issue":"8","key":"6113_CR32","doi-asserted-by":"publisher","first-page":"e808","DOI":"10.1111\/aos.12981","volume":"94","author":"CL Oakley","year":"2016","unstructured":"Oakley CL, Vote BJ (2016) Aqueous chlorhexidine (0.1%) is an effective alternative to povidone-iodine for intravitreal injection prophylaxis. Acta ophthalmologica 94(8):e808\u2013e809. https:\/\/doi.org\/10.1111\/aos.12981","journal-title":"Acta ophthalmologica"},{"issue":"8","key":"6113_CR33","doi-asserted-by":"publisher","first-page":"1885","DOI":"10.1007\/s00417-013-2274-y","volume":"251","author":"H Shimada","year":"2013","unstructured":"Shimada H, Hattori T, Mori R, Nakashizuka H, Fujita K, Yuzawa M (2013) Minimizing the endophthalmitis rate following intravitreal injections using 0.25% povidone-iodine irrigation and surgical mask. Graefes Arch Clin Exp Ophthalmol Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 251(8):1885\u20131890. https:\/\/doi.org\/10.1007\/s00417-013-2274-y","journal-title":"Graefes Arch Clin Exp Ophthalmol Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie"},{"issue":"1","key":"6113_CR34","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1128\/CMR.12.1.147","volume":"12","author":"G McDonnell","year":"1999","unstructured":"McDonnell G, Russell AD (1999) Antiseptics and disinfectants: activity, action, and resistance. Clin Microbiol Rev 12(1):147\u2013179. https:\/\/doi.org\/10.1128\/CMR.12.1.147","journal-title":"Clin Microbiol Rev"}],"container-title":["Graefe's Archive for Clinical and Experimental Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00417-023-06113-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00417-023-06113-1\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00417-023-06113-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,30]],"date-time":"2023-09-30T06:05:14Z","timestamp":1696053914000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00417-023-06113-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5,18]]},"references-count":34,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["6113"],"URL":"https:\/\/doi.org\/10.1007\/s00417-023-06113-1","relation":{},"ISSN":["0721-832X","1435-702X"],"issn-type":[{"value":"0721-832X","type":"print"},{"value":"1435-702X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,5,18]]},"assertion":[{"value":"3 October 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 April 2023","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 May 2023","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 May 2023","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 June 2023","order":5,"name":"change_date","label":"Change Date","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Update","order":6,"name":"change_type","label":"Change Type","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The given name and family name of the first author has been incorrectly identified in the XML version. This has been updated and corrected: \"Edoardo\" as given name and \"Trovato Battagliola\" as family name.","order":7,"name":"change_details","label":"Change Details","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Ethics Committee of Sapienza University of Rome (Nov. 8th, 2021\/No. 345235).","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"Informed consent was obtained from all individual participants included in the study.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}