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Median mean defect:\u2009\u2212\u20095.8 (\u2212\u200911.9;\u2009\u2212\u20092.6) db. Principle of the IOPstim: an empty balloon with a diameter of 8\u00a0mm is positioned on the eye, laterally of the limbus. Under observation of the central retinal vein (CRV), the examiner inflates the balloon. As soon as the CRV starts pulsation, the inflation is stopped and the IOP is measured, equaling the RVP at this moment. In the CLD, the pulsation of the CRV is observed with a contact lens. The RVP is calculated from the attachment force applied when pulsation appears.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Course of examinations<\/jats:title>\n                <jats:p>Three single measurements of RVP in quick succession with both methods. The sequence of the two methods was randomized. The means of the three RVP measurements were compared.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>Pressures in mmHg. RVP: IOPstim: 19.4\u2009\u00b1\u20095.4 (mean\u2009\u00b1\u2009SD), CLD: 20.3\u2009\u00b1\u20095.9. Range of three single measurements: IOPstim: 2.9\u2009\u00b1\u20091.5, CLD: 2.2\u2009\u00b1\u20091.1. The differences were RVP<jats:sub>IOPstim<\/jats:sub>\u2009\u2212\u2009RVP<jats:sub>CLD<\/jats:sub>\u2009=\u2009\u2009\u2212\u20090.94\u2009\u00b1\u20091.15, and approximately normally distributed. Bland\u2013Altman analysis: only one data point was 0.5\u00a0mmHg higher than the upper line of agreement. The confidence interval of this line was 0.65\u00a0mmHg. Concordance correlation coefficient according to Lin (CCC): 0.96. Intraclass correlation coefficient: both methods, 0.94.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>In both methods, the range of the single measurements may be taken as a sign of good reliability, the CCC of 0.96 as a sign of a very good agreement. At the mean, the IOPstim RVP values were 1\u00a0mmHg lower than those obtained with the CLD. This difference may be due to the different directions of the prevailing force vectors induced by the instruments. The IOPstim seems applicable in glaucoma diagnostics.<\/jats:p>\n                \n              <\/jats:sec>","DOI":"10.1007\/s00417-023-06326-4","type":"journal-article","created":{"date-parts":[[2024,1,12]],"date-time":"2024-01-12T09:02:33Z","timestamp":1705050153000},"page":"1633-1639","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Measurement of the retinal venous pressure with a new instrument in patients with primary open angle glaucoma"],"prefix":"10.1007","volume":"262","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8689-2913","authenticated-orcid":false,"given":"Richard","family":"Stodtmeister","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aline","family":"Menzel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Klimova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Herber","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karin. 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Informed consent was obtained from all individual participants included in this study. The study was approved by the ethics committee of the Technical University of Dresden (EK 322062019).","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The corresponding author received a travel grant by Imedos GmbH and is consultant to this company. All other coauthors certify that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The funding company played no role in the design or conduct of this research.Open access has been possible by DEAL.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclaimer"}}]}}