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The NLR, PLR, LMR, and SII values were calculated on both the first day and at the end of the first month after birth. The association between development of ROP and other risk factors were analyzed using univariate analysis and multivariate logistic regression analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of patients, 92 infants were diagnosed with ROP. Laser treatment was administered to 36 infants. The postnatal first-day NLR and SII values were higher in infants with ROP than in infants without ROP (p\u2009&lt;\u20090.001 for both). Postnatal first-month NLR, LMR, and SII values were higher in infants with ROP (p\u2009&lt;\u20090.001, p\u2009=\u20090.007, and p\u2009&lt;\u20090.001, respectively). In multivariate analyses, postnatal first-day NLR and first-month LMR values were regarded as independent risk factors for the development of ROP (OR:8.867 and 1.286, p\u2009=\u20090.002 and p\u2009=\u20090.009, respectively). In multivariate analyses performed for laser treatment requirement, postnatal first-month PLR and SII values were determined as independent risk factors (OR:0.951 and 1.011, respectively, p\u2009=\u20090.004 for both).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Postnatal first-day NLR and first-month LMR values were determined as independent risk factors for the development of ROP. For the requirement of laser treatment, the postnatal first-month PLR and SII values were determined as independent risk factors.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00417-024-06493-y","type":"journal-article","created":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T05:02:23Z","timestamp":1713934943000},"page":"3125-3134","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Predictive role of systemic immune-inflammation index and neutrophil\/lymphocyte ratio values in infants with retinopathy of prematurity"],"prefix":"10.1007","volume":"262","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4771-4698","authenticated-orcid":false,"given":"O\u011fuzhan","family":"Oruz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2006-2906","authenticated-orcid":false,"given":"Mehmet Serdar","family":"Dervi\u015fo\u011fullar\u0131","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-1188-5936","authenticated-orcid":false,"given":"M\u00fczeyyen Ezgi","family":"\u00d6ktem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9019-423X","authenticated-orcid":false,"given":"Caner","family":"\u0130nceka\u015f","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,4,24]]},"reference":[{"issue":"6","key":"6493_CR1","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1053\/j.semperi.2019.05.001","volume":"43","author":"BA Darlow","year":"2019","unstructured":"Darlow BA, Gilbert C (2019) Retinopathy of prematurity - A world update. 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