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Fluorescein (FA) and indocyanine (ICGA) angiography circulatory times were arterial time (FA<jats:sub>AT<\/jats:sub>), start (FA<jats:sub>startLF<\/jats:sub>) and end (FA<jats:sub>endLF<\/jats:sub>) of laminar flow, and arterial time (ICGA<jats:sub>AT<\/jats:sub>), respectively. OCT angiography VDs were superficial (VD<jats:sub>SCP<\/jats:sub>) and deep (VD<jats:sub>DCP<\/jats:sub>) RCPs and CC (VD<jats:sub>CC<\/jats:sub>) VDs. Correlation and regression analysis were performed after adjusting for confounding factors.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>177 eyes of 177 patients (mean age: 65.2\u2009\u00b1\u200915.9\u00a0years, n\u2009=\u200992 with and 85 without CVR) were included. VD<jats:sub>SCP<\/jats:sub> and VD<jats:sub>DCP<\/jats:sub> were significantly inversely correlated with FA<jats:sub>AT<\/jats:sub>, FA<jats:sub>startLF<\/jats:sub> and FA<jats:sub>endLF<\/jats:sub> likewise VD<jats:sub>CC<\/jats:sub> with ICGA<jats:sub>AT<\/jats:sub>. Correlations were stronger in patients without CVR than with CVR. CVR, FA<jats:sub>AT<\/jats:sub>, FA<jats:sub>startLF<\/jats:sub> and FA<jats:sub>endLF<\/jats:sub> were more strongly correlated with VD<jats:sub>DCP<\/jats:sub> than VD<jats:sub>SCP<\/jats:sub>. FA<jats:sub>AT<\/jats:sub>, FA<jats:sub>startLF<\/jats:sub> and FA<jats:sub>endLF<\/jats:sub> significantly impacted VD<jats:sub>SCP<\/jats:sub> and VD<jats:sub>DCP<\/jats:sub>, likewise ICGA<jats:sub>AT<\/jats:sub> impacted VD<jats:sub>DCP<\/jats:sub>. VD<jats:sub>DCP<\/jats:sub> was most strongly impacted by FA<jats:sub>AT<\/jats:sub> and FA<jats:sub>startLF<\/jats:sub>.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>Ocular and pre-ocular circulatory dynamics significantly impacted RCPs and CC VDs, especially deep RCP.<\/jats:p>\n                \n              <\/jats:sec>","DOI":"10.1007\/s00417-024-06544-4","type":"journal-article","created":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T10:02:01Z","timestamp":1722420121000},"page":"3867-3879","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of preocular and ocular circulatory dynamics on the vascular density of retinal capillary plexuses and choriocapillaris"],"prefix":"10.1007","volume":"262","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9569-687X","authenticated-orcid":false,"given":"Rodolphe","family":"Vall\u00e9e","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dilsah","family":"K\u00f6rpe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean-No\u00ebl","family":"Vall\u00e9e","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2441-545X","authenticated-orcid":false,"given":"Georgios N.","family":"Tsiropoulos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5145-5126","authenticated-orcid":false,"given":"Daniela","family":"Gallo Castro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irmela","family":"Mantel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Constantin J.","family":"Pournaras","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aude","family":"Ambresin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,7,31]]},"reference":[{"key":"6544_CR1","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/j.brainres.2017.07.025","volume":"1672","author":"MW Country","year":"2017","unstructured":"Country MW (2017) Retinal metabolism: A comparative look at energetics in the retina. 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