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SCLs were fitted on each eye of CL wearers, and the lower tear meniscus was imaged using OCT before CL insertion, immediately afterward, and reimaged 2, 5 and 10\u00a0h after insertion. Tear meniscus parameters, including tear meniscus height (TMH), depth (TMD), turbidity, and percentage area occupied by particles (PAOP) were measured in all groups.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Turbidity and PAOP measurements at baseline in SCLW were significantly higher than in other groups (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). There was no significant difference between TMH, TMD, turbidity, and PAOP parameters calculated at baseline visit and two hours after SCL insertion in all groups (<jats:italic>p<\/jats:italic>\u2009&gt;\u20090.05 for 2 comparisons). The symptomatic SCL users had a significant decrease in TMH and TMD in the fifth hour. The turbidity and PAOP measurements of SCLW and ASCW at the fifth and tenth hours were significantly higher than those of NCLW (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>TMD and height TMH decrease throughout the day in all participants; however, a significant decrease in these parameters was observed only in symptomatic SCL users at the fifth hour, at the earliest. As the duration of CL wear increases, turbidity and PAOP even in asymptomatic SCL wearers become significantly higher than those in healthy non-CL wearers.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Key Messages<\/jats:title>\n            <jats:p>\n              <jats:bold>What Is Known<\/jats:bold>\n            <\/jats:p>\n            <jats:p>\u2022 Contact lens wear is associated with an increased risk of dry eye.<\/jats:p>\n            <jats:p>\u2022 Tear volume decreases gradually during contact lens wear.<\/jats:p>\n            <jats:p>\n              <jats:bold>What Is New<\/jats:bold>\n            <\/jats:p>\n            <jats:p>\u2022 Tear meniscus turbidity and particle area occupied by particles (PAOP) were higher in symptomatic contact lens wearers and they increase gradually during contact lens wear.<\/jats:p>\n            <jats:p>\u2022 Tear meniscus turbidity and PAOP may be measures of how well the tear film and meniscus are functioning in contact lens wearers.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s00417-024-06606-7","type":"journal-article","created":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T05:03:14Z","timestamp":1723006994000},"page":"171-179","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The analysis of tear meniscus parameters during daily soft contact lens wear using optical coherence tomography"],"prefix":"10.1007","volume":"263","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4849-3698","authenticated-orcid":false,"given":"Levent","family":"Dogan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gurcan Dogukan","family":"Arslan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,8,7]]},"reference":[{"issue":"32","key":"6606_CR1","doi-asserted-by":"publisher","first-page":"841","DOI":"10.15585\/mmwr.mm6632a2","volume":"66","author":"JR Cope","year":"2016","unstructured":"Cope JR, Collier SA, Nethercut H et al (2016) (2017) Risk Behaviors for Contact Lens-Related Eye Infections Among Adults and Adolescents - United States. 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