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Complete blood count (CBC) parameters and serum levels of total cholesterol, low-density lipoprotein (LDL), high-density lipoprotein (HDL), and triglycerides (TG) were obtained from electronic medical records. The neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and monocyte-to-HDL ratio (MHR) were calculated for each participant. Group differences were analyzed statistically.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The monocyte-to-HDL ratio was significantly higher in the conjunctivochalasis group (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.023), while hemoglobin levels were significantly lower (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.001). No additional significant differences were observed in other hematological or lipid parameters.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study is the first to demonstrate an elevated monocyte-to-HDL ratio in patients with conjunctivochalasis. The concurrent reduction in hemoglobin levels provides further support for a potential systemic association. These findings suggest that conjunctivochalasis may involve not only localized ocular changes but also systemic inflammatory processes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00417-025-07101-3","type":"journal-article","created":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T10:22:20Z","timestamp":1767954140000},"page":"1053-1058","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The role of systemic inflammation in patients with conjunctivochalasis"],"prefix":"10.1007","volume":"264","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6521-3934","authenticated-orcid":false,"given":"Mine","family":"Koru Toprak","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6353-4558","authenticated-orcid":false,"given":"Aydin","family":"Toprak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,1,9]]},"reference":[{"key":"7101_CR1","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1016\/j.ajo.2008.07.022","volume":"147","author":"T Mimura","year":"2009","unstructured":"Mimura T, Yamagami S, Usui T, Funatsu H, Mimura Y, Noma H et al (2009) Changes of conjunctivochalasis with age in a hospital-based study. 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