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All participants underwent a complete eye visit including Goldmann applanation tonometry (GAT), corneal biomechanical properties evaluation performed with Corvis ST (CST) and corneal morphological evaluation through Oculus Pentacam.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      In this study, GAT-measured IOP was significantly lower in DM1 patients (12.63\u2009\u00b1\u20092.12 mmHg) compared to controls (16.65\u2009\u00b1\u20092.24 mmHg) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). DM1 patients, compared to the healthy subjects, showed significant differences in many parameters related to the corneal deformation. In particular, DM1 patients displayed, among others, higher mean values of highest concavity deformation amplitude (1.19\u00a0mm vs. 1.04\u00a0mm) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0008), of deflection amplitude measured at applanation 2 (0.15\u00a0mm vs. 0.11\u00a0mm) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0008), deflection amplitude measured at highest concavity (0.98\u00a0mm vs. 0.87\u00a0mm) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0008) and maximum length of deflection amplitude (1.05\u00a0mm vs. 0.88\u00a0mm) (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0008).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The findings presented in this study suggest that the corneas of patients affected by DM1 are more susceptible to external stimuli than those of healthy subjects. Thus, GAT may underestimate IOP in DM1 patients due to altered corneal biomechanics.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s00417-026-07156-w","type":"journal-article","created":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T05:10:07Z","timestamp":1772169007000},"page":"1773-1779","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Intraocular pressure and corneal biomechanics in patients affected by myotonic dystrophy type 1"],"prefix":"10.1007","volume":"264","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1578-7155","authenticated-orcid":false,"given":"Michele","family":"Lanza","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa","family":"Boccia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianna","family":"Scutifero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luigi","family":"Serra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa","family":"Cangiano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esther","family":"Picillo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Italo","family":"Fattore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Nigro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesca","family":"Simonelli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,2,27]]},"reference":[{"issue":"6","key":"7156_CR1","doi-asserted-by":"publisher","first-page":"507","DOI":"10.1212\/CPJ.0000000000000531","volume":"8","author":"T Ashizawa","year":"2018","unstructured":"Ashizawa T, Gagnon C, Groh WJ et al (2018) Consensus-based care recommendations for adults with myotonic dystrophy type 1. 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