{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T05:10:55Z","timestamp":1788585055799,"version":"build-2803163510"},"reference-count":6,"publisher":"Springer Science and Business Media LLC","issue":"8","license":[{"start":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T00:00:00Z","timestamp":1774569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T00:00:00Z","timestamp":1774569600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Graefes Arch Clin Exp Ophthalmol"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1007\/s00417-026-07218-z","type":"journal-article","created":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T06:40:33Z","timestamp":1774593633000},"page":"2421-2425","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Intravitreal plungerless injector device (IPLID) for anterior chamber paracentesis: a novel approach to aqueous humor sampling"],"prefix":"10.1007","volume":"264","author":[{"given":"Juan B.","family":"Yepez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felipe A.","family":"Murati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Igor","family":"Kozak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Fernando","family":"Arevalo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,27]]},"reference":[{"key":"7218_CR1","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1186\/s40942-019-0157-z","volume":"5","author":"S Saxena","year":"2019","unstructured":"Saxena S, Lai TY, Koizumi H, Farah ME, Ferrara D, Pelayes D, Sato T, Meyer CH, Murray T, International Pharmacokinetic Collaboration (2019) Anterior chamber paracentesis during intravitreal injections in observational trials: effectiveness and safety and effects. Int J Retina Vitreous 5:8. https:\/\/doi.org\/10.1186\/s40942-019-0157-zPMID: 30873293; PMCID: PMC6402161","journal-title":"Int J Retina Vitreous"},{"key":"7218_CR2","doi-asserted-by":"publisher","first-page":"821","DOI":"10.3928\/0090-4481-19881101-14","volume":"19","author":"DR May","year":"1988","unstructured":"May DR, Noll FG (1988) An improved approach to aqueous paracentesis. Ophthalmic Surg 19:821\u2013822. https:\/\/doi.org\/10.3928\/0090-4481-19881101-14. PMID: 3222046","journal-title":"Ophthalmic Surg"},{"key":"7218_CR3","doi-asserted-by":"publisher","first-page":"548","DOI":"10.1136\/bjophthalmol-2016-309650","volume":"101","author":"K Kitazawa","year":"2017","unstructured":"Kitazawa K, Sotozono C, Koizumi N, Nagata K, Inatomi T, Sasaki H, Kinoshita S (2017) Safety of anterior chamber paracentesis using a 30-gauge needle integrated with a specially designed disposable pipette. Br J Ophthalmol 101:548\u2013550. https:\/\/doi.org\/10.1136\/bjophthalmol-2016-309650. PMID: 28100481","journal-title":"Br J Ophthalmol"},{"key":"7218_CR4","doi-asserted-by":"publisher","DOI":"10.1089\/bio.2020.0039","author":"Y Qu","year":"2020","unstructured":"Qu Y, Chen Y, Zhao C (2020) Testing a novel disposable aqueous humor collector: an approach to improve safety, accuracy, and efficiency. Biopreserv Biobank 18:449\u2013453. https:\/\/doi.org\/10.1089\/bio.2020.0039. PMID: 32808816","journal-title":"Biopreserv Biobank"},{"key":"7218_CR5","doi-asserted-by":"publisher","first-page":"535","DOI":"10.2147\/OPTH.S494755","volume":"19","author":"JB Yepez","year":"2025","unstructured":"Yepez JB, Murati FA, Petitto M, Kozak I, Arevalo JF (2025) Intravitreal Plungerless Injector Device (IPLID): an innovative intravitreal injector device. Clin Ophthalmol 19:535\u2013541. https:\/\/doi.org\/10.2147\/OPTH.S494755PMID: 39967785; PMCID: PMC11834656","journal-title":"Clin Ophthalmol"},{"key":"7218_CR6","doi-asserted-by":"publisher","first-page":"548","DOI":"10.1136\/bjophthalmol-2016-309650","volume":"101","author":"K Kitazawa","year":"2017","unstructured":"Kitazawa K, Sotozono C, Koizumi N, Nagata K, Inatomi T, Sasaki H, Kinoshita S (2017) Safety of anterior chamber paracentesis using a 30-gauge needle integrated with a specially designed disposable pipette. Br J Ophthalmol 101:548\u2013550. https:\/\/doi.org\/10.1136\/bjophthalmol-2016-309650. PMID: 28100481","journal-title":"Br J Ophthalmol"}],"container-title":["Graefe's Archive for Clinical and Experimental Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00417-026-07218-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00417-026-07218-z","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00417-026-07218-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T14:22:16Z","timestamp":1787149336000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00417-026-07218-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,27]]},"references-count":6,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["7218"],"URL":"https:\/\/doi.org\/10.1007\/s00417-026-07218-z","relation":{},"ISSN":["0721-832X","1435-702X"],"issn-type":[{"value":"0721-832X","type":"print"},{"value":"1435-702X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,27]]},"assertion":[{"value":"14 November 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"18 March 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"21 March 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 March 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This study was approved by the Institutional Review Board (IRB) of the Eye Clinic, Maracaibo, Venezuela. According to local regulations, a specific institutional review board (IRB) approval number is not issued in this setting. Written informed consent was obtained from all patients prior to their participation. As this study was conducted at a single private ophthalmology clinic, the study adhered to ethical guidelines and the tenets of the Declaration of Helsinki.","order":1,"name":"Ethics","label":"Ethics approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Dr. Yepez has financial and proprietary interest in the device, the rest the authors do not have any financial or proprietary interest in the materials presented in this paper.Non-financial interests: none.","order":2,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"not applicable.","order":3,"name":"Ethics","label":"Clinical trial number","group":{"name":"EthicsHeading","label":"Declarations"}}]}}