{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T22:58:04Z","timestamp":1785452284776,"version":"3.56.0"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T00:00:00Z","timestamp":1785369600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T00:00:00Z","timestamp":1785369600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Graefes Arch Clin Exp Ophthalmol"],"DOI":"10.1007\/s00417-026-07432-9","type":"journal-article","created":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T05:32:14Z","timestamp":1785389534000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Choroidal vascularity and thickness modulation with topical nepafenac after phacoemulsification: a comparative study in diabetic and non-diabetic eyes"],"prefix":"10.1007","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3178-2880","authenticated-orcid":false,"given":"Mustafa","family":"Duran","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1507-8148","authenticated-orcid":false,"given":"Caner","family":"\u00d6zt\u00fcrk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7968-4876","authenticated-orcid":false,"given":"Selim","family":"Cevher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0347-0828","authenticated-orcid":false,"given":"Sabriye","family":"Bolat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,30]]},"reference":[{"issue":"1","key":"7432_CR1","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1097\/ICU.0000000000001092","volume":"36","author":"H Hashemi","year":"2025","unstructured":"Hashemi H, Fayaz F, Hashemi A, Khabazkhoob M (2025) Global prevalence of cataract surgery. Curr Opin Ophthalmol 36(1):10\u201317. https:\/\/doi.org\/10.1097\/ICU.0000000000001092","journal-title":"Curr Opin Ophthalmol"},{"issue":"1","key":"7432_CR2","doi-asserted-by":"publisher","first-page":"27569","DOI":"10.1038\/s41598-025-13174-1","volume":"15","author":"S-H Lee","year":"2025","unstructured":"Lee S-H, Chiu Y-C, Tsai P-C, Wang J-H, Chiu C-J (2025) Femtosecond laser-assisted cataract surgery versus conventional phacoemulsification cataract surgery: a meta-analysis of randomized controlled trials. Sci Rep 15(1):27569. https:\/\/doi.org\/10.1038\/s41598-025-13174-1","journal-title":"Sci Rep"},{"key":"7432_CR3","doi-asserted-by":"publisher","unstructured":"Chen K-Y, Chan H-C, Chan C-M (2025) How does diabetes shape the landscape of cataract development and surgical success? a systematic review and meta-analysis. Endocrine 1\u201316. https:\/\/doi.org\/10.1007\/s12020-025-04374-w","DOI":"10.1007\/s12020-025-04374-w"},{"issue":"1","key":"7432_CR4","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1007\/s00417-006-0377-4","volume":"245","author":"RF Degenring","year":"2007","unstructured":"Degenring RF, Vey S, Kamppeter B, Budde WM, Jonas JB, Sauder G (2007) Effect of uncomplicated phacoemulsification on the central retina in diabetic and non-diabetic subjects. Graefes Arch Clin Exp Ophthalmol 245(1):18\u201323. https:\/\/doi.org\/10.1007\/s00417-006-0377-4","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"3","key":"7432_CR5","doi-asserted-by":"publisher","first-page":"362","DOI":"10.4103\/2008-322X.143378","volume":"9","author":"ES Shin","year":"2014","unstructured":"Shin ES, Sorenson CM, Sheibani N (2014) Diabetes and retinal vascular dysfunction. J Ophthalmic Vis Res 9(3):362\u2013373. https:\/\/doi.org\/10.4103\/2008-322X.143378","journal-title":"J Ophthalmic Vis Res"},{"key":"7432_CR6","doi-asserted-by":"publisher","first-page":"37","DOI":"10.2147\/jir.s5706","volume":"2","author":"H Cho","year":"2009","unstructured":"Cho H, Madu A (2009) Etiology and treatment of the inflammatory causes of cystoid macular edema. J Inflamm Res 2:37\u201343. https:\/\/doi.org\/10.2147\/jir.s5706","journal-title":"J Inflamm Res"},{"issue":"5","key":"7432_CR7","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1080\/08820538.2023.2170716","volume":"38","author":"E \u00d6zyol","year":"2023","unstructured":"\u00d6zyol E, \u00d6zyol P, G\u00fcnel-Karadeniz P (2023) editors. The use of prostaglandin analogues and cystoid macular edema after uneventful cataract surgery: a systematic review and meta-analysis. Semin Ophthalmol 38 5 490\u2013497 https:\/\/doi.org\/10.1080\/08820538.2023.2170716","journal-title":"Semin Ophthalmol"},{"key":"7432_CR8","doi-asserted-by":"publisher","first-page":"147","DOI":"10.2147\/opth.s4684","volume":"3","author":"SM Hariprasad","year":"2009","unstructured":"Hariprasad SM, Akduman L, Clever JA, Ober M, Recchia FM, Mieler WF (2009) Treatment of cystoid macular edema with the new-generation NSAID nepafenac 0.1%. Clin Ophthalmol 3:147\u2013154. https:\/\/doi.org\/10.2147\/opth.s4684","journal-title":"Clin Ophthalmol"},{"issue":"3","key":"7432_CR9","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1016\/j.ajo.2009.04.008","volume":"148","author":"K Sayanagi","year":"2009","unstructured":"Sayanagi K, Sharma S, Kaiser PK (2009) Comparison of retinal thickness measurements between three-dimensional and radial scans on spectral-domain optical coherence tomography. Am J Ophthalmol 148(3):431\u2013438. https:\/\/doi.org\/10.1016\/j.ajo.2009.04.008","journal-title":"Am J Ophthalmol"},{"issue":"1","key":"7432_CR10","doi-asserted-by":"publisher","first-page":"21090","DOI":"10.1038\/srep21090","volume":"6","author":"R Agrawal","year":"2016","unstructured":"Agrawal R, Gupta P, Tan K-A, Cheung CMG, Wong T-Y, Cheng C-Y (2016) Choroidal vascularity index as a measure of vascular status of the choroid: measurements in healthy eyes from a population-based study. Sci Rep 6(1):21090. https:\/\/doi.org\/10.1038\/srep21090","journal-title":"Sci Rep"},{"issue":"02","key":"7432_CR11","doi-asserted-by":"publisher","first-page":"113","DOI":"10.5935\/0004-2749.20160033","volume":"79","author":"JMBB Garcia","year":"2016","unstructured":"Garcia JMBB, Isaac DLC (2016) \u00c1vila MPd. Dexamethasone 0.7\u00a0mg implants in the management of pseudophakic cystoid macular edema. Arq Bras Oftalmol 79(02):113\u2013115. https:\/\/doi.org\/10.5935\/0004-2749.20160033","journal-title":"Arq Bras Oftalmol"},{"issue":"11","key":"7432_CR12","doi-asserted-by":"publisher","first-page":"742","DOI":"10.3928\/1081597X-20131021-03","volume":"29","author":"T Schultz","year":"2013","unstructured":"Schultz T, Joachim SC, Kuehn M, Dick HB (2013) Changes in prostaglandin levels in patients undergoing femtosecond laser-assisted cataract surgery. J Refract Surg 29(11):742\u2013747. https:\/\/doi.org\/10.3928\/1081597X-20131021-03","journal-title":"J Refract Surg"},{"issue":"1","key":"7432_CR13","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1186\/s12886-017-0405-7","volume":"17","author":"S McCafferty","year":"2017","unstructured":"McCafferty S, Harris A, Kew C, Kassm T, Lane L, Levine J, Raven M (2017) Pseudophakic cystoid macular edema prevention and risk factors; prospective study with adjunctive once daily topical nepafenac 0.3% versus placebo. BMC Ophthalmol 17(1):16. https:\/\/doi.org\/10.1186\/s12886-017-0405-7","journal-title":"BMC Ophthalmol"},{"issue":"1","key":"7432_CR14","doi-asserted-by":"publisher","first-page":"249","DOI":"10.1167\/iovs.10-6001","volume":"52","author":"H Xu","year":"2011","unstructured":"Xu H, Chen M, Forrester JV, Lois N (2011) Cataract surgery induces retinal pro-inflammatory gene expression and protein secretion. Invest Ophthalmol Vis Sci 52(1):249\u2013255. https:\/\/doi.org\/10.1167\/iovs.10-6001","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"7432_CR15","doi-asserted-by":"publisher","first-page":"188","DOI":"10.5935\/0004-2749.20180040","volume":"81","author":"M Xie","year":"2018","unstructured":"Xie M, Huang L, Xu G (2018) Prostaglandin antagonist relieves blood-retinal barrier breakdown induced by anterior segment intraocular surgery in a rat model. Arq Bras Oftalmol 81:188\u2013194. https:\/\/doi.org\/10.5935\/0004-2749.20180040","journal-title":"Arq Bras Oftalmol"},{"key":"7432_CR16","doi-asserted-by":"publisher","first-page":"1608376","DOI":"10.3389\/fphar.2025.1608376","volume":"26","author":"AK Stark","year":"2025","unstructured":"Stark AK, Penn JS (2025) Prostaglandin E2 stimulates opposing effects on inner and outer blood-retina barrier function. Front Pharmacol 26:16:1608376. https:\/\/doi.org\/10.3389\/fphar.2025.1608376","journal-title":"Front Pharmacol"},{"issue":"1","key":"7432_CR17","doi-asserted-by":"publisher","first-page":"329","DOI":"10.1186\/s12974-024-03319-w","volume":"21","author":"AK Stark","year":"2024","unstructured":"Stark AK, Penn JS (2024) Prostanoid signaling in retinal cells elicits inflammatory responses relevant to early-stage diabetic retinopathy. J Neuroinflammation 21(1):329. https:\/\/doi.org\/10.1186\/s12974-024-03319-w","journal-title":"J Neuroinflammation"},{"issue":"2","key":"7432_CR18","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1185\/030079906x89775","volume":"22","author":"R Lindstrom","year":"2006","unstructured":"Lindstrom R, Kim T (2006) Ocular permeation and inhibition of retinal inflammation: an examination of data and expert opinion on the clinical utility of nepafenac. Curr Med Res Opin 22(2):397\u2013404. https:\/\/doi.org\/10.1185\/030079906x89775","journal-title":"Curr Med Res Opin"},{"key":"7432_CR19","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.exer.2015.10.009","volume":"145","author":"JE Chastain","year":"2016","unstructured":"Chastain JE, Sanders ME, Curtis MA, Chemuturi NV, Gadd ME, Kapin MA, Markwardt KL, Dahlin DC (2016) Distribution of topical ocular nepafenac and its active metabolite amfenac to the posterior segment of the eye. Exp Eye Res 145:58\u201367. https:\/\/doi.org\/10.1016\/j.exer.2015.10.009","journal-title":"Exp Eye Res"},{"issue":"1","key":"7432_CR20","doi-asserted-by":"publisher","first-page":"2501325","DOI":"10.1155\/2018\/2501325","volume":"2018","author":"S Zeng","year":"2018","unstructured":"Zeng S, Liang C, He Y, Chen Y, Zhao Q, Dai S, Cheng F, Zhang J, Jiang X (2018) Changes of subfoveal choroidal thickness after cataract surgery: a meta-analysis. J Ophthalmol 2018(1):2501325. https:\/\/doi.org\/10.1155\/2018\/2501325","journal-title":"J Ophthalmol"},{"issue":"1","key":"7432_CR21","doi-asserted-by":"publisher","first-page":"102","DOI":"10.1186\/s12886-020-01371-7","volume":"20","author":"Y Ikegami","year":"2020","unstructured":"Ikegami Y, Takahashi M, Amino K (2020) Evaluation of choroidal thickness, macular thickness, and aqueous flare after cataract surgery in patients with and without diabetes: a prospective randomized study. BMC Ophthalmol 20(1):102. https:\/\/doi.org\/10.1186\/s12886-020-01371-7","journal-title":"BMC Ophthalmol"},{"issue":"2","key":"7432_CR22","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1097\/IAE.0000000000000298","volume":"35","author":"PN Brito","year":"2015","unstructured":"Brito PN, Rosas VM, Coentr\u00e3o LM, Carneiro \u00c2V, Rocha-Sousa A, Brand\u00e3o E, Falc\u00e3o-Reis F, Falc\u00e3o MA (2015) Evaluation of visual acuity, macular status, and subfoveal choroidal thickness changes after cataract surgery in eyes with diabetic retinopathy. Retina 35(2):294\u2013302. https:\/\/doi.org\/10.1097\/IAE.0000000000000298","journal-title":"Retina"},{"issue":"1","key":"7432_CR23","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.joco.2018.07.004","volume":"31","author":"H Torabi","year":"2019","unstructured":"Torabi H, Sadraei M, Jadidi K, Alishiri A-A (2019) Choroidal thickness changes following cataract surgery in patients with type 2 diabetes mellitus. J Curr Ophthalmol 31(1):49\u201354. https:\/\/doi.org\/10.1016\/j.joco.2018.07.004","journal-title":"J Curr Ophthalmol"},{"issue":"4","key":"7432_CR24","doi-asserted-by":"publisher","first-page":"369","DOI":"10.1177\/1479164119841536","volume":"16","author":"VC-H Yip","year":"2019","unstructured":"Yip VC-H, Laude A, Tan KA, Ding J, Wong E, Agrawal R (2019) A longitudinal study of choroidal changes following cataract surgery in patients with diabetes. Diab Vasc Dis Res 16(4):369\u2013377. https:\/\/doi.org\/10.1177\/1479164119841536","journal-title":"Diab Vasc Dis Res"},{"issue":"5","key":"7432_CR25","doi-asserted-by":"publisher","first-page":"2319","DOI":"10.1177\/1120672120976041","volume":"31","author":"S Cevher","year":"2021","unstructured":"Cevher S, Aydo\u011fdu G (2021) How does nepafenac affect the choroidal thickness after uneventful cataract surgery? Eur J Ophthalmol 31(5):2319\u20132328. https:\/\/doi.org\/10.1177\/1120672120976041","journal-title":"Eur J Ophthalmol"},{"issue":"7","key":"7432_CR26","doi-asserted-by":"publisher","first-page":"e612","DOI":"10.1111\/aos.13044","volume":"94","author":"KA Tan","year":"2016","unstructured":"Tan KA, Laude A, Yip V, Loo E, Wong EP, Agrawal R (2016) Choroidal vascularity index\u2013a novel optical coherence tomography parameter for disease monitoring in diabetes mellitus? Acta Ophthalmol 94(7):e612\u2013e6. https:\/\/doi.org\/10.1111\/aos.13044","journal-title":"Acta Ophthalmol"},{"issue":"1","key":"7432_CR27","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1186\/s12886-018-0749-7","volume":"18","author":"H Chen","year":"2018","unstructured":"Chen H, Wu Z, Chen Y, He M, Wang J (2018) Short-term changes of choroidal vascular structures after phacoemulsification surgery. BMC Ophthalmol 18(1):81. https:\/\/doi.org\/10.1186\/s12886-018-0749-7","journal-title":"BMC Ophthalmol"},{"issue":"1","key":"7432_CR28","doi-asserted-by":"publisher","first-page":"5839837","DOI":"10.1155\/2020\/5839837","volume":"2020","author":"H Yao","year":"2020","unstructured":"Yao H, Gao S, Liu X, Zhou Y, Cheng Y, Shen X (2020) Choroidal structural changes assessed with swept-source optical coherence tomography after cataract surgery in eyes with diabetic retinopathy. J Ophthalmol 2020(1):5839837. https:\/\/doi.org\/10.1155\/2020\/5839837","journal-title":"J Ophthalmol"},{"issue":"14","key":"7432_CR29","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1167\/tvst.10.14.33","volume":"1","author":"W Kongwattananon","year":"2021","unstructured":"Kongwattananon W, Kumar A, Oyeniran E, Sen HN, Kodati S (2021) Changes in choroidal vascularity index (CVI) in intermediate uveitis. Transl Vis Sci Technol 1(14):33. https:\/\/doi.org\/10.1167\/tvst.10.14.33","journal-title":"Transl Vis Sci Technol"}],"container-title":["Graefe's Archive for Clinical and Experimental Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00417-026-07432-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00417-026-07432-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00417-026-07432-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T22:04:46Z","timestamp":1785449086000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s00417-026-07432-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,30]]},"references-count":29,"alternative-id":["7432"],"URL":"https:\/\/doi.org\/10.1007\/s00417-026-07432-9","relation":{},"ISSN":["0721-832X","1435-702X"],"issn-type":[{"value":"0721-832X","type":"print"},{"value":"1435-702X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,30]]},"assertion":[{"value":"15 June 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 June 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 July 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 July 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","label":"Competing interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no conflict of interests.","order":2,"name":"Ethics","label":"Disclosure","group":{"name":"EthicsHeading","label":"Declarations"}}]}}