{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T03:39:41Z","timestamp":1792726781468,"version":"4.5.0"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T00:00:00Z","timestamp":1792713600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T00:00:00Z","timestamp":1792713600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"name":"Research Project on Educational and Teaching Reform of Capital Medical University","award":["2025JYY196"],"award-info":[{"award-number":["2025JYY196"]}]},{"DOI":"10.13039\/501100004826","name":"Natural Science Foundation of Beijing Municipality","doi-asserted-by":"publisher","award":["Grant no. Z220012"],"award-info":[{"award-number":["Grant no. Z220012"]}],"id":[{"id":"10.13039\/501100004826","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82220108017, 82141128"],"award-info":[{"award-number":["82220108017, 82141128"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010270","name":"Capital Health Research and Development of Special Fund","doi-asserted-by":"publisher","award":["2024-1-2052"],"award-info":[{"award-number":["2024-1-2052"]}],"id":[{"id":"10.13039\/501100010270","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Science & Technology Project of Beijing Municipal Science & Technology Commission","award":["Z201100005520045"],"award-info":[{"award-number":["Z201100005520045"]}]},{"name":"Sanming Project of Medicine in Shenzhen","award":["No. SZSM202311018"],"award-info":[{"award-number":["No. SZSM202311018"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Graefes Arch Clin Exp Ophthalmol"],"DOI":"10.1007\/s00417-026-07570-0","type":"journal-article","created":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T03:16:03Z","timestamp":1792725363000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Integrated multimodal assessment of retinal oxygenation, hemodynamics, and neurovisual function in retinal vein occlusion"],"prefix":"10.1007","author":[{"given":"Haowen","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingyuan","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinyuan","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ximeng","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuehao","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zi","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haihan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiyi","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiong","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingpeng","family":"Miao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongpeng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinrong","family":"Duan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiying","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangyu","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiushi","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuanqing","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2386-0989","authenticated-orcid":false,"given":"Wenbin","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,23]]},"reference":[{"key":"7570_CR1","doi-asserted-by":"publisher","unstructured":"Lendzioszek M, Bryl A, Poppe E, Zorena K, Mrugacz M (2024) Retinal Vein Occlusion-Background Knowledge and Foreground Knowledge Prospects-A Review. J Clin Med 13(13). https:\/\/doi.org\/10.3390\/jcm13133950","DOI":"10.3390\/jcm13133950"},{"key":"7570_CR2","doi-asserted-by":"publisher","unstructured":"Munk MR, Ceklic L, Stillenmunkes R, Chaudhary V, Waheed N, Chhablani J, de Smet MD, Tillmann A (2024) Integrated Assessment of OCT, Multimodal Imaging, and Cytokine Markers for Predicting Treatment Responses in Retinal Vein Occlusion Associated Macular Edema: A Comparative Review of Anti-VEGF and Steroid Therapies. Diagnostics (Basel) 1714. https:\/\/doi.org\/10.3390\/diagnostics14171983","DOI":"10.3390\/diagnostics14171983"},{"issue":"1","key":"7570_CR3","doi-asserted-by":"publisher","first-page":"010427","DOI":"10.7189\/jogh.09.010427","volume":"9","author":"P Song","year":"2019","unstructured":"Song P, Xu Y, Zha M, Zhang Y, Rudan I (2019) Global epidemiology of retinal vein occlusion: a systematic review and meta-analysis of prevalence, incidence, and risk factors. J Glob Health 9(1):010427. https:\/\/doi.org\/10.7189\/jogh.09.010427","journal-title":"J Glob Health"},{"key":"7570_CR4","doi-asserted-by":"publisher","unstructured":"Darabu\u015f DM, D\u0103r\u0103bu\u015f RG, Munteanu M (2025) The Diagnosis and Treatment of Branch Retinal Vein Occlusions: An Update. Biomedicines 13(1). https:\/\/doi.org\/10.3390\/biomedicines13010105","DOI":"10.3390\/biomedicines13010105"},{"issue":"2","key":"7570_CR5","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1097\/apo.0000000000000598","volume":"12","author":"F Romano","year":"2023","unstructured":"Romano F, Lamanna F, Gabrielle PH, Teo KYC, Battaglia Parodi M, Iacono P, Fraser-Bell S, Cornish EE, Nassisi M, Viola F, Agarwal A, Samanta A, Chhablani J, Staurenghi G, Invernizzi A (2023) Update on Retinal Vein Occlusion. Asia Pac J Ophthalmol (Phila) 12(2):196\u2013210. https:\/\/doi.org\/10.1097\/apo.0000000000000598","journal-title":"Asia Pac J Ophthalmol (Phila)"},{"issue":"Suppl 1","key":"7570_CR6","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1186\/s40942-019-0196-5","volume":"5","author":"NF Callaway","year":"2019","unstructured":"Callaway NF, Mruthyunjaya P (2019) Widefield imaging of retinal and choroidal tumors. Int J Retina Vitreous 5(Suppl 1):49. https:\/\/doi.org\/10.1186\/s40942-019-0196-5","journal-title":"Int J Retina Vitreous"},{"issue":"5","key":"7570_CR7","doi-asserted-by":"publisher","first-page":"679","DOI":"10.1016\/j.survophthal.2019.02.004","volume":"64","author":"IS Kornblau","year":"2019","unstructured":"Kornblau IS, El-Annan JF (2019) Adverse reactions to fluorescein angiography: A comprehensive review of the literature. Surv Ophthalmol 64(5):679\u2013693. https:\/\/doi.org\/10.1016\/j.survophthal.2019.02.004","journal-title":"Surv Ophthalmol"},{"key":"7570_CR8","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1186\/s40942-015-0005-8","volume":"1","author":"TE de Carlo","year":"2015","unstructured":"de Carlo TE, Romano A, Waheed NK, Duker JS (2015) A review of optical coherence tomography angiography (OCTA). Int J Retina Vitreous 1:5. https:\/\/doi.org\/10.1186\/s40942-015-0005-8","journal-title":"Int J Retina Vitreous"},{"key":"7570_CR9","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.preteyeres.2017.11.003","volume":"64","author":"RF Spaide","year":"2018","unstructured":"Spaide RF, Fujimoto JG, Waheed NK, Sadda SR, Staurenghi G (2018) Optical coherence tomography angiography. Prog Retin Eye Res 64:1\u201355. https:\/\/doi.org\/10.1016\/j.preteyeres.2017.11.003","journal-title":"Prog Retin Eye Res"},{"key":"7570_CR10","doi-asserted-by":"publisher","first-page":"5498125","DOI":"10.1155\/2017\/5498125","volume":"2017","author":"R Hua","year":"2017","unstructured":"Hua R, Wang H (2017) Dark Signals in the Choroidal Vasculature on Optical Coherence Tomography Angiography: An Artefact or Not? J Ophthalmol 2017:5498125. https:\/\/doi.org\/10.1155\/2017\/5498125","journal-title":"J Ophthalmol"},{"issue":"8","key":"7570_CR11","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1117\/1.Jbo.24.8.080901","volume":"24","author":"W Heeman","year":"2019","unstructured":"Heeman W, Steenbergen W, van Dam G, Boerma EC (2019) Clinical applications of laser speckle contrast imaging: a review. J Biomed Opt 24(8):1\u201311. https:\/\/doi.org\/10.1117\/1.Jbo.24.8.080901","journal-title":"J Biomed Opt"},{"issue":"5","key":"7570_CR12","doi-asserted-by":"publisher","first-page":"466","DOI":"10.1111\/j.1755-3768.2011.02109.x","volume":"90","author":"SH Hardarson","year":"2012","unstructured":"Hardarson SH, Stef\u00e1nsson E (2012) Oxygen saturation in branch retinal vein occlusion. Acta Ophthalmol 90(5):466\u2013470. https:\/\/doi.org\/10.1111\/j.1755-3768.2011.02109.x","journal-title":"Acta Ophthalmol"},{"issue":"6","key":"7570_CR13","doi-asserted-by":"publisher","first-page":"871","DOI":"10.1016\/j.ajo.2010.06.020","volume":"150","author":"SH Hardarson","year":"2010","unstructured":"Hardarson SH, Stef\u00e1nsson E (2010) Oxygen saturation in central retinal vein occlusion. Am J Ophthalmol 150(6):871\u2013875. https:\/\/doi.org\/10.1016\/j.ajo.2010.06.020","journal-title":"Am J Ophthalmol"},{"issue":"8","key":"7570_CR14","doi-asserted-by":"publisher","first-page":"3247","DOI":"10.1167\/iovs.19-27227","volume":"60","author":"P Karamian","year":"2019","unstructured":"Karamian P, Burford J, Farzad S, Blair NP, Shahidi M (2019) Alterations in Retinal Oxygen Delivery, Metabolism, and Extraction Fraction During Bilateral Common Carotid Artery Occlusion in Rats. Invest Ophthalmol Vis Sci 60(8):3247\u20133253. https:\/\/doi.org\/10.1167\/iovs.19-27227","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"1","key":"7570_CR15","doi-asserted-by":"publisher","first-page":"e0244702","DOI":"10.1371\/journal.pone.0244702","volume":"16","author":"EO Contreras","year":"2021","unstructured":"Contreras EO, Dearing CG, Ashinhurst CA, Fish BA, Hossain SN, Rey AM, Silva PD, Thompson S (2021) Pupillary reflex and behavioral masking responses to light as functional measures of retinal degeneration in mice. PLoS ONE 16(1):e0244702. https:\/\/doi.org\/10.1371\/journal.pone.0244702","journal-title":"PLoS ONE"},{"issue":"3","key":"7570_CR16","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1007\/s00417-016-3496-6","volume":"255","author":"P Richter","year":"2017","unstructured":"Richter P, Wilhelm H, Peters T, Luedtke H, Kurtenbach A, Jaegle H, Wilhelm B (2017) The diagnostic accuracy of chromatic pupillary light responses in diseases of the outer and inner retina. Graefes Arch Clin Exp Ophthalmol 255(3):519\u2013527. https:\/\/doi.org\/10.1007\/s00417-016-3496-6","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"7570_CR17","doi-asserted-by":"publisher","first-page":"909","DOI":"10.1038\/s41433-022-02007-4","volume":"36","author":"The Royal College of Ophthalmologists","year":"2022","unstructured":"The Royal College of Ophthalmologists (2022) Retinal vein occlusion (RVO) guideline: executive summary. Eye 36:909\u2013912. https:\/\/doi.org\/10.1038\/s41433-022-02007-4","journal-title":"Eye"},{"issue":"10","key":"7570_CR18","doi-asserted-by":"publisher","first-page":"5400","DOI":"10.1364\/BOE.465991","volume":"13","author":"X Feng","year":"2022","unstructured":"Feng X, Jin Z, Zhou Z, Gao M, Jiang C, Hu Y, Lu Y, Li J, Ren Q, Zhou C (2022) Retinal oxygen kinetics imaging and analysis (ROKIA) based on the integration and fusion of structural-functional imaging. Biomedical Opt Express 13(10):5400\u20135417. https:\/\/doi.org\/10.1364\/BOE.465991","journal-title":"Biomedical Opt Express"},{"issue":"2","key":"7570_CR19","doi-asserted-by":"publisher","first-page":"e202100285","DOI":"10.1002\/jbio.202100285","volume":"15","author":"X Feng","year":"2022","unstructured":"Feng X, Yu Y, Zou D, Jin Z, Zhou C, Liu G, Fujimoto JG, Li C, Lu Y, Ren Q (2022) Functional imaging of human retina using integrated multispectral and laser speckle contrast imaging. J Biophotonics 15(2):e202100285. https:\/\/doi.org\/10.1002\/jbio.202100285","journal-title":"J Biophotonics"},{"issue":"12","key":"7570_CR20","doi-asserted-by":"publisher","first-page":"1737","DOI":"10.1136\/bjo-2023-323283","volume":"108","author":"Z Jin","year":"2024","unstructured":"Jin Z, Chen X, Jiang C, Feng X, Zou D, Lu Y, Li J, Ren Q, Zhou C (2024) Predicting the cognitive impairment with multimodal ophthalmic imaging and artificial neural network for community screening. Br J Ophthalmol 108(12):1737\u20131742. https:\/\/doi.org\/10.1136\/bjo-2023-323283","journal-title":"Br J Ophthalmol"},{"issue":"3","key":"7570_CR21","doi-asserted-by":"publisher","first-page":"219","DOI":"10.1016\/j.bandc.2008.08.013","volume":"68","author":"R Lencer","year":"2008","unstructured":"Lencer R, Trillenberg P (2008) Neurophysiology and neuroanatomy of smooth pursuit in humans. Brain Cogn 68(3):219\u2013228. https:\/\/doi.org\/10.1016\/j.bandc.2008.08.013","journal-title":"Brain Cogn"},{"issue":"11","key":"7570_CR22","doi-asserted-by":"publisher","first-page":"3587","DOI":"10.1007\/s00417-022-05722-6","volume":"260","author":"H Al Zoubi","year":"2022","unstructured":"Al Zoubi H, Riemer T, Simon R, Vilser W, Hasan S, Meller D, Augsten R, Hammer M (2022) Optic disc blood perfusion and oxygenation in glaucoma. Graefes Arch Clin Exp Ophthalmol 260(11):3587\u20133595. https:\/\/doi.org\/10.1007\/s00417-022-05722-6","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"1","key":"7570_CR23","doi-asserted-by":"publisher","first-page":"79","DOI":"10.3233\/jad-150457","volume":"49","author":"AB Einarsdottir","year":"2016","unstructured":"Einarsdottir AB, Hardarson SH, Kristjansdottir JV, Bragason DT, Snaedal J, Stef\u00e1nsson E (2016) Retinal oximetry imaging in Alzheimer\u2019s disease. J Alzheimers Dis 49(1):79\u201383. https:\/\/doi.org\/10.3233\/jad-150457","journal-title":"J Alzheimers Dis"},{"issue":"6","key":"7570_CR24","doi-asserted-by":"publisher","first-page":"624","DOI":"10.1111\/aos.15066","volume":"100","author":"AV Belamkar","year":"2022","unstructured":"Belamkar AV, Jabbehdari S, Harris A, Hajrasouliha AR (2022) Clinical implications of retinal oximetry in retinal vein occlusion: a review. Acta Ophthalmol 100(6):624\u2013631. https:\/\/doi.org\/10.1111\/aos.15066","journal-title":"Acta Ophthalmol"},{"issue":"10","key":"7570_CR25","doi-asserted-by":"publisher","first-page":"1653","DOI":"10.1007\/s00417-014-2849-2","volume":"253","author":"TS Eliasdottir","year":"2015","unstructured":"Eliasdottir TS, Bragason D, Hardarson SH, Kristjansdottir G, Stef\u00e1nsson E (2015) Venous oxygen saturation is reduced and variable in central retinal vein occlusion. Graefe\u2019s Archive For Clinical and Experimental Ophthalmology\u2009=\u2009Albrecht Von Graefes Archiv Fur Klinische. Und Experimentelle Ophthalmologie 253(10):1653\u20131661. https:\/\/doi.org\/10.1007\/s00417-014-2849-2","journal-title":"Und Experimentelle Ophthalmologie"},{"issue":"9","key":"7570_CR26","doi-asserted-by":"publisher","first-page":"1208","DOI":"10.1136\/bjophthalmol-2013-304580","volume":"98","author":"S Traustason","year":"2014","unstructured":"Traustason S, la Cour M, Larsen M (2014) Retinal vascular oximetry during ranibizumab treatment of central retinal vein occlusion. Br J Ophthalmol 98(9):1208\u20131211. https:\/\/doi.org\/10.1136\/bjophthalmol-2013-304580","journal-title":"Br J Ophthalmol"},{"issue":"9","key":"7570_CR27","doi-asserted-by":"publisher","first-page":"1481","DOI":"10.1177\/0271678x17722095","volume":"38","author":"W Lin","year":"2018","unstructured":"Lin W, Powers WJ (2018) Oxygen metabolism in acute ischemic stroke. J Cereb Blood Flow Metab 38(9):1481\u20131499. https:\/\/doi.org\/10.1177\/0271678x17722095","journal-title":"J Cereb Blood Flow Metab"},{"key":"7570_CR28","unstructured":"RN P (2011) Regulation of Tissue Oxygenation. Morgan & Claypool Life Sciences Chap. 8"},{"issue":"7","key":"7570_CR29","doi-asserted-by":"publisher","first-page":"e1141","DOI":"10.1111\/aos.14744","volume":"99","author":"SK Jeppesen","year":"2021","unstructured":"Jeppesen SK, S\u00edn M, Hardarson SH, Bek T (2021) Retinal oximetry does not predict 12-month visual outcome after anti-VEGF treatment for central retinal vein occlusion: a multicentre study. Acta Ophthalmol 99(7):e1141\u2013e1145. https:\/\/doi.org\/10.1111\/aos.14744","journal-title":"Acta Ophthalmol"},{"issue":"8","key":"7570_CR30","doi-asserted-by":"publisher","first-page":"3488","DOI":"10.1167\/iovs.18-23872","volume":"59","author":"N Kiyota","year":"2018","unstructured":"Kiyota N, Shiga Y, Ichinohasama K, Yasuda M, Aizawa N, Omodaka K, Honda N, Kunikata H, Nakazawa T (2018) The Impact of Intraocular Pressure Elevation on Optic Nerve Head and Choroidal Blood Flow. Investig Ophthalmol Vis Sci 59(8):3488\u20133496. https:\/\/doi.org\/10.1167\/iovs.18-23872","journal-title":"Investig Ophthalmol Vis Sci"},{"issue":"7","key":"7570_CR31","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1089\/jop.2013.0130","volume":"30","author":"F Semeraro","year":"2014","unstructured":"Semeraro F, Russo A, Rizzoni D, Danzi P, Morescalchi F, Costagliola C (2014) Diameters and wall-to-lumen ratio of retinal arterioles in patients with retinal vein occlusion before and after treatment with dexamethasone intravitreal implants. J Ocul Pharmacol Ther 30(7):573\u2013579. https:\/\/doi.org\/10.1089\/jop.2013.0130","journal-title":"J Ocul Pharmacol Ther"},{"issue":"7","key":"7570_CR32","first-page":"1450","volume":"38","author":"G Donati","year":"1997","unstructured":"Donati G, Pournaras CJ, Pizzolato GP, Tsacopoulos M (1997) Decreased nitric oxide production accounts for secondary arteriolar constriction after retinal branch vein occlusion. Invest Ophthalmol Vis Sci 38(7):1450\u20131457","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"7570_CR33","doi-asserted-by":"publisher","first-page":"8407206","DOI":"10.1155\/2019\/8407206","volume":"2019","author":"Y Yang","year":"2019","unstructured":"Yang Y, Xu C, Chen Y, Liang JJ, Xu Y, Chen SL, Huang S, Yang Q, Cen LP, Pang CP, Sun XH, Ng TK (2019) Green Tea Extract Ameliorates Ischemia-Induced Retinal Ganglion Cell Degeneration in Rats. Oxid Med Cell Longev 2019:8407206. https:\/\/doi.org\/10.1155\/2019\/8407206","journal-title":"Oxid Med Cell Longev"},{"issue":"3","key":"7570_CR34","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1097\/IAE.0b013e3182a2e746","volume":"34","author":"C-S Kim","year":"2014","unstructured":"Kim C-S, Shin K-S, Lee H-J, Jo Y-J, Kim J-Y (2014) Sectoral retinal nerve fiber layer thinning in branch retinal vein occlusion. Retina (Philadelphia Pa) 34(3):525\u2013530. https:\/\/doi.org\/10.1097\/IAE.0b013e3182a2e746","journal-title":"Retina (Philadelphia Pa)"},{"issue":"11","key":"7570_CR35","doi-asserted-by":"publisher","first-page":"1506","DOI":"10.1136\/bjophthalmol-2015-308106","volume":"100","author":"RA Alshareef","year":"2016","unstructured":"Alshareef RA, Barteselli G, You Q, Goud A, Jabeen A, Rao HL, Jabeen A, Chhablani J (2016) In vivo evaluation of retinal ganglion cells degeneration in eyes with branch retinal vein occlusion. Br J Ophthalmol 100(11):1506\u20131510. https:\/\/doi.org\/10.1136\/bjophthalmol-2015-308106","journal-title":"Br J Ophthalmol"},{"issue":"2","key":"7570_CR36","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1111\/aos.14544","volume":"99","author":"JB Ducloyer","year":"2021","unstructured":"Ducloyer JB, Bensaber S, Khanna RK, Cochard C, Lebreton O, Le Meur G, Lebranchu P, Arsene S, Weber M (2021) Predictive values of initial semi-quantitative assessment of relative afferent pupillary defect for neovascularization in central retinal vein occlusion. Acta Ophthalmol 99(2):215\u2013220. https:\/\/doi.org\/10.1111\/aos.14544","journal-title":"Acta Ophthalmol"},{"issue":"Pt 5","key":"7570_CR37","doi-asserted-by":"publisher","first-page":"624","DOI":"10.1038\/eye.1995.151","volume":"9","author":"A Ramsay","year":"1995","unstructured":"Ramsay A, Williamson TH, Parks S, Keating D (1995) Crossed polarising filters to measure relative afferent pupillary defects: reproducibility, correlation with neutral density filters and use in central retinal vein occlusion. Eye 9(Pt 5):624\u2013628","journal-title":"Eye"},{"issue":"10","key":"7570_CR38","doi-asserted-by":"publisher","first-page":"1823","DOI":"10.1097\/iae.0000000000001158","volume":"36","author":"RF Spaide","year":"2016","unstructured":"Spaide RF (2016) RETINAL VASCULAR CYSTOID MACULAR EDEMA: Review and New Theory. Retina 36(10):1823\u20131842. https:\/\/doi.org\/10.1097\/iae.0000000000001158","journal-title":"Retina"},{"key":"7570_CR39","doi-asserted-by":"publisher","first-page":"108296","DOI":"10.1016\/j.visres.2023.108296","volume":"211","author":"P Verghese","year":"2023","unstructured":"Verghese P, Nystr\u00f6m M, Foulsham T, McGraw PV (2023) Eye movements in visual impairment. Vis Res 211:108296. https:\/\/doi.org\/10.1016\/j.visres.2023.108296","journal-title":"Vis Res"},{"issue":"3","key":"7570_CR40","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1007\/s10384-018-0586-5","volume":"62","author":"H Iijima","year":"2018","unstructured":"Iijima H (2018) Mechanisms of vision loss in eyes with macular edema associated with retinal vein occlusion. Jpn J Ophthalmol 62(3):265\u2013273. https:\/\/doi.org\/10.1007\/s10384-018-0586-5","journal-title":"Jpn J Ophthalmol"},{"key":"7570_CR41","doi-asserted-by":"crossref","unstructured":"Lisberger SG, Morris EJ, Tychsen L (1987) Visual motion processing and sensory-motor integration for smooth pursuit eye movements. Annu Rev Neurosci 10","DOI":"10.1146\/annurev.ne.10.030187.000525"},{"issue":"4","key":"7570_CR42","doi-asserted-by":"publisher","first-page":"953","DOI":"10.1152\/jn.1986.56.4.953","volume":"56","author":"L Tychsen","year":"1986","unstructured":"Tychsen L, Lisberger SG (1986) Visual motion processing for the initiation of smooth-pursuit eye movements in humans. J Neurophysiol 56(4):953\u2013968","journal-title":"J Neurophysiol"},{"key":"7570_CR43","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1016\/j.ajo.2023.07.028","volume":"256","author":"A Au","year":"2023","unstructured":"Au A, Ip M, Blodi BA, Scott IU, Oden NL, Van Veldhuisen PC, Sarraf D (2023) OCT grading system of macular infarction predicts vision in participants with central retinal or hemiretinal vein occlusion: a secondary analysis of SCORE2. Am J Ophthalmol 256:55\u201362. https:\/\/doi.org\/10.1016\/j.ajo.2023.07.028","journal-title":"Am J Ophthalmol"},{"key":"7570_CR44","doi-asserted-by":"publisher","first-page":"104762","DOI":"10.1016\/j.mvr.2024.104762","volume":"157","author":"S Yin","year":"2025","unstructured":"Yin S, Wang J, Zhu J et al (2025) A multimodal imaging approach to investigate retinal oxygen and vascular dynamics, and neural dysfunction in bietti crystalline dystrophy. Microvasc Res 157:104762. https:\/\/doi.org\/10.1016\/j.mvr.2024.104762","journal-title":"Microvasc Res"},{"issue":"8","key":"7570_CR45","doi-asserted-by":"publisher","first-page":"e70854","DOI":"10.1002\/cam4.70854","volume":"14","author":"H Zhang","year":"2025","unstructured":"Zhang H, Zhu J, Liu Y et al (2025) Retinal Oxygen Kinetics and Hemodynamics in Choroidal Melanoma After Iodine-125 Plaque Radiotherapy Using a Novel Structural-Functional Imaging Analysis System. Cancer Med 14(8):e70854. https:\/\/doi.org\/10.1002\/cam4.70854","journal-title":"Cancer Med"},{"key":"7570_CR46","doi-asserted-by":"publisher","first-page":"4945","DOI":"10.1038\/s41598-019-41296-w","volume":"9","author":"AV Rukmini","year":"2019","unstructured":"Rukmini AV, Chew MC, Finkelstein MT et al (2019) Effects of low and moderate refractive errors on chromatic pupillometry. Sci Rep 9:4945. https:\/\/doi.org\/10.1038\/s41598-019-41296-w","journal-title":"Sci Rep"},{"issue":"6","key":"7570_CR47","doi-asserted-by":"publisher","first-page":"e896","DOI":"10.1111\/aos.14070","volume":"97","author":"R Osaka","year":"2019","unstructured":"Osaka R, Nakano Y, Takasago Y, Fujita T, Yamashita A, Shiragami C, Muraoka Y, Tsujikawa A (2019) Retinal oximetry in branch retinal vein occlusion. Acta Ophthalmol 97(6):e896\u2013e901. https:\/\/doi.org\/10.1111\/aos.14070","journal-title":"Acta Ophthalmol"}],"container-title":["Graefe's Archive for Clinical and Experimental Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00417-026-07570-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00417-026-07570-0","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s00417-026-07570-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T03:16:07Z","timestamp":1792725367000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s00417-026-07570-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,23]]},"references-count":47,"alternative-id":["7570"],"URL":"https:\/\/doi.org\/10.1007\/s00417-026-07570-0","relation":{},"ISSN":["0721-832X","1435-702X"],"issn-type":[{"value":"0721-832X","type":"print"},{"value":"1435-702X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,23]]},"assertion":[{"value":"5 May 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"8 September 2026","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 October 2026","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 October 2026","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"All participants signed the informed consent form. The Medical Ethics Committee of the Beijing Tongren Hospital peer-reviewed and approved the related documents and all study protocols for the collection and use of participant data. The committee\u2019s reference number is TRECKY2018-056. The research followed the tenets of the Declaration of Helsinki. All information is kept confidential, and the patients\u2019 basic information will not be made available to other non-researchers or organizations.","order":1,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}]}}