{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T05:46:38Z","timestamp":1791351998352,"version":"4.3.1"},"reference-count":47,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2003,5,1]],"date-time":"2003-05-01T00:00:00Z","timestamp":1051747200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Histochem Cell Biol"],"published-print":{"date-parts":[[2003,5]]},"DOI":"10.1007\/s00418-003-0524-5","type":"journal-article","created":{"date-parts":[[2019,12,12]],"date-time":"2019-12-12T03:17:13Z","timestamp":1576120633000},"page":"415-422","source":"Crossref","is-referenced-by-count":40,"title":["First case of feline spongiform encephalopathy in a captive cheetah born in France: PrPsc analysis in various tissues revealed unexpected targeting of kidney and adrenal gland"],"prefix":"10.1007","volume":"119","author":[{"given":"Stephane","family":"Lezmi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Bencsik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eoin","family":"Monks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"Petit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"Baron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2003,5,1]]},"reference":[{"key":"0524_CR1","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1136\/vr.141.11.270","volume":"141","author":"Baron","year":"1997","unstructured":"Baron T, Belli P, Madec JY, Moutou F, Vitaud C, Savey M (1997) Spongiform encephalopathy in an imported cheetah in France. Vet Rec 141:270\u2013271","journal-title":"Vet Rec"},{"key":"0524_CR2","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.1099\/0022-1317-77-8-1925","volume":"77","author":"Beekes","year":"1996","unstructured":"Beekes M, Baldauf E, Diringer H (1996) Sequential appearance and accumulation of pathognomonic markers in the central nervous system of hamsters orally infected with scrapie. J Gen Virol 77:1925\u20131934","journal-title":"J Gen Virol"},{"key":"0524_CR3","unstructured":"Bell JE (1996) Neuropathological diagnosis of human prion disease. PrP immunocytochemical techniques. In: Baker HRRM (ed) Prion disease. Humana, Tottowa, pp\u00a059\u201383"},{"key":"0524_CR4","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1111\/j.1365-2990.1997.tb01182.x","volume":"23","author":"Bell","year":"1997","unstructured":"Bell JE, Gentleman SM, Ironside JW, McCardle L, Lantos PL, Doey L, Lowe J, Fergusson J, Luthert P, McQuaid S, Allen IV (1997) Prion protein immunocytochemistry: UK five centre consensus report. Neuropathol Appl Neurobiol 23:26\u201335","journal-title":"Neuropathol Appl Neurobiol"},{"key":"0524_CR5","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1080\/135502801753170309","volume":"7","author":"A Bencsik","year":"2001","unstructured":"Bencsik A, Lezmi S, Baron T (2001) Autonomous nervous system innervation of lymphoid territories in spleen: A possible involvement of noradrenergic neurons for prion neuroinvasion in natural scrapie. J. Neurovirol. 7:447\u2013453.","journal-title":"J. Neurovirol."},{"key":"0524_CR6","unstructured":"Bj\u00f6rklund A, H\u00f6kfelt T (1985) Handbook of chemical neuroanatomy\u2014Classical transmitters in the CNS. Amsterdam, Elsevier."},{"key":"0524_CR7","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1126\/science.6815801","volume":"218","author":"Bolton","year":"1982","unstructured":"Bolton DC, McKinley MP, Prusiner SB (1982) Identification of a protein that purifies with the scrapie prion. Science 218:1309\u20131311","journal-title":"Science"},{"key":"0524_CR8","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1136\/vr.136.17.444","volume":"136","author":"Bratberg","year":"1995","unstructured":"Bratberg B, Ueland K, Wells G (1995) Feline spongiform encephalopathy in a cat in Norway. Vet Rec 136:444","journal-title":"Vet Rec"},{"key":"0524_CR9","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1038\/383685a0","volume":"383","author":"Collinge","year":"1996","unstructured":"Collinge J, Sidle KCL, Meads J, Ironside J, Hill AF (1996) Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD. Nature 383:685\u2013690","journal-title":"Nature"},{"key":"0524_CR10","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1177\/002215540104901205","volume":"49","author":"Debeer","year":"2001","unstructured":"Debeer SOS, Baron TGM, Bencsik AA (2001) Immunohistochemistry of PrPsc within bovine spongiform encephalopathy brain samples with graded autolysis. J Histochem Cytochem 49:1519\u20131524","journal-title":"J Histochem Cytochem"},{"key":"0524_CR11","doi-asserted-by":"publisher","first-page":"431","DOI":"10.1007\/s007050050516","volume":"144","author":"Elsen","year":"1999","unstructured":"Elsen JM, Amigues Y, Schelcher F, Ducrocq V, Andr\u00e9oletti O, Eychenne F, Vu Tien Khang J, Poivey JP, Lantier F, Laplanche J-L (1999) Genetic susceptibility and transmission factors in scrapie: detailed analysis of an epidemic in a closed flock of Romanov. Arch Virol 144:431\u2013445","journal-title":"Arch Virol"},{"key":"0524_CR12","doi-asserted-by":"publisher","first-page":"36487","DOI":"10.1074\/jbc.C000579200","volume":"275","author":"Ettaiche","year":"2000","unstructured":"Ettaiche M, Pichot R, Vincent JP, Chabry J (2000) In vivo cytotoxicity of the prion protein fragment 106\u2013126. J Biol Chem 275:36487\u201336490","journal-title":"J Biol Chem"},{"key":"0524_CR13","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1136\/vr.134.17.449","volume":"134","author":"Fraser","year":"1994","unstructured":"Fraser H, Pearson GR, McConnell I, Bruce ME, Wyatt JM, Gruffydd-Jones TJ (1994) Transmission of feline spongiform encephalopathy to mice. Vet Rec 134:449\u2013449","journal-title":"Vet Rec"},{"key":"0524_CR14","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1210\/endo.141.3.7345","volume":"141","author":"Gayrard","year":"2000","unstructured":"Gayrard V, Picard-Hagen N, Grino M, Sauze N, Grandjean C, Galea J, Andreoletti O, Schelcher F, Toutain PL (2000) Major hypercorticism is an endocrine feature of ewes with naturally occurring scrapie. Endocrinology 141:988\u2013994","journal-title":"Endocrinology"},{"key":"0524_CR15","doi-asserted-by":"crossref","first-page":"2813","DOI":"10.1099\/0022-1317-81-11-2813","volume":"81","author":"Glatzel","year":"2000","unstructured":"Glatzel M, Aguzzi A (2000) PrPC expression in the peripheral nervous system is a determinant of prion neuroinvasion. J Gen Virol 81:2813\u20132821","journal-title":"J Gen Virol"},{"key":"0524_CR16","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1006\/nbdi.1996.0019","volume":"3","author":"Groschup","year":"1996","unstructured":"Groschup M, Weiland F, Straub O, Pfaff E (1996) Detection of scrapie agent in the peripheral nervous system of a diseased sheep. Neurobiol Dis 3:191\u2013195","journal-title":"Neurobiol Dis"},{"key":"0524_CR17","unstructured":"Guyton M, Hall J (2000) Textbook of medical physiology, 10th\u00a0edn. Saunders, Philadelphia"},{"key":"0524_CR18","doi-asserted-by":"publisher","first-page":"342","DOI":"10.1167\/iovs.01-1273","volume":"44","author":"Head","year":"2003","unstructured":"Head MW, Northcott V, Rennison K, Ritchie D, McCardle L, Bunn TJR, McLennan NF, Ironside JW, Tullo AB, Bonshek RE (2003) Prion protein accumulation in eyes of patients with sporadic and variant Creutzfeldt-Jakob disease. Invest Ophthalmol Vis Sci 44:342\u2013346","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"0524_CR19","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1038\/38925","volume":"389","author":"Hill","year":"1997","unstructured":"Hill A, Desbruslais M, Joiner S, Sidle KCL, Gowland I, Collinge J (1997) The same prion strain causes vCJD and BSE. Nature 389:448\u2013450","journal-title":"Nature"},{"key":"0524_CR20","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/S0140-6736(98)12075-5","volume":"353","author":"Hill","year":"1999","unstructured":"Hill AF, Butterworth RJ, Joiner S, Jackson G, Rossor MN, Thomas DJ, Frosh A (1999) Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples. Lancet 353:183\u2013189","journal-title":"Lancet"},{"key":"0524_CR21","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1007\/BF01718157","volume":"141","author":"Hunter","year":"1996","unstructured":"Hunter N, Foster JD, Goldmann W, Stear MJ, Hope J, Bostock C (1996) Natural scrapie in a closed flock of Cheviot sheep occurs only in specific PrP genotypes. Arch Virol 141:809\u2013824","journal-title":"Arch Virol"},{"key":"0524_CR46","doi-asserted-by":"crossref","first-page":"2897","DOI":"10.1099\/0022-1317-83-11-2897","volume":"83","author":"Hunter","year":"2002","unstructured":"Hunter N, Foster J, Chong A, McCutcheon S, Parnham D, Eaton S, MacKenzie C, Houston F (2002) Transmission of prion diseases by blood transfusion. J Gen Virol 83:2897\u20132905","journal-title":"J Gen Virol"},{"key":"0524_CR22","doi-asserted-by":"crossref","unstructured":"Jeffrey M, McGovern G, Martin S, Goodsir CM, Brown KL (2000) Cellular and sub-cellular localisation of PrP in the lymphoreticular system of mice and sheep. Arch Virol 23\u201338","DOI":"10.1007\/978-3-7091-6308-5_3"},{"key":"0524_CR23","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1053\/jcpa.2001.0476","volume":"125","author":"Jeffrey","year":"2001","unstructured":"Jeffrey M, Martin S, Thomson JR, Dingwall WS, BegaraMcGorum I, Gonzalez L (2001) Onset and distribution of tissue PrP accumulation in scrapie-affected Suffolk sheep as demonstrated by sequential necropsies and tonsillar biopsies. J Comp Pathol 125:48\u201357","journal-title":"J Comp Pathol"},{"key":"0524_CR24","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1097\/00041327-200020020-00011","volume":"20","author":"Katz","year":"2000","unstructured":"Katz BJ, Warner JE, Digre KB, Creel DJ (2000) Selective loss of the electroretinogram B-wave in a patient with Creutzfeldt-Jakob disease. J Neuroophthalmol 20:116\u2013118","journal-title":"J Neuroophthalmol"},{"key":"0524_CR27","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1128\/JCM.34.5.1228-1231.1996","volume":"34","author":"Keulen","year":"1996","unstructured":"Keulen LJM van, Schreuder BEC, Meloen RH, Mooij-Harkes G, Vromans MEW, Langeveld JPM (1996) Immunohistochemical detection of prion in lymphoid tissues of sheep with natural scrapie. J Clin Microbiol 34:1228\u20131231","journal-title":"J Clin Microbiol"},{"key":"0524_CR28","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1053\/jcpa.1998.0300","volume":"121","author":"Keulen","year":"1999","unstructured":"Keulen LJM van, Schreuder BEC, Vromans MEW, Langeveld JPM, Smits MA (1999) Scrapie-associated prion protein in the gastro-intestinal tract of sheep with natural scrapie. J Comp Pathol 121:55\u201363","journal-title":"J Comp Pathol"},{"key":"0524_CR29","unstructured":"Keulen LJM van, Schreuder BEC, Vromans MEW, Langeveld JPM, Smits MA (2000) Pathogenesis of natural scrapie in sheep. Arch Virol 57\u201371"},{"key":"0524_CR25","doi-asserted-by":"crossref","first-page":"21","DOI":"10.3181\/00379727-189-42774","volume":"189","author":"Kim","year":"1988","unstructured":"Kim Y, Carp R, Callahan S, Wisniewski H (1988) Adrenal involvement in scrapie-induced obesity. Proc Soc Exp Biol Med 189:21\u201327","journal-title":"Proc Soc Exp Biol Med"},{"key":"0524_CR26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1750-3639.2002.tb00417.x","volume":"12","author":"Kovacs","year":"2002","unstructured":"Kovacs GG, Head MW, Hegyi I, Bunn TJ, Flicker H, Hainfellner JA, McCardle L, Laszlo L, Jarius C, Ironside JW, Budka H (2002) Immunohistochemistry for the prion protein: comparison of different monoclonal antibodies in human prion disease subtypes. Brain Pathol 12:1\u201311","journal-title":"Brain Pathol"},{"key":"0524_CR30","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0165-2427(01)00323-3","volume":"82","author":"Lezmi","year":"2001","unstructured":"Lezmi S, Bencsik A, Baron T (2001) CNA42 monoclonal antibody identifies FDC as PrPsc accumulating cells in the spleen of scrapie affected sheep. Vet Immunol Immunopathol 82:1\u20138","journal-title":"Vet Immunol Immunopathol"},{"key":"0524_CR31","doi-asserted-by":"publisher","first-page":"9320","DOI":"10.1128\/JVI.75.19.9320-9327.2001","volume":"75","author":"McBride","year":"2001","unstructured":"McBride PA, SchulzSchaeffer WJ, Donaldson M, Bruce M, Diringer H, Kretzschmar HA, Beekes M (2001) Early spread of scrapie from the gastrointestinal tract to the central nervous system involves autonomic fibers of the splanchnic and vagus nerves. J Virol 75:9320\u20139327","journal-title":"J Virol"},{"key":"0524_CR32","doi-asserted-by":"publisher","first-page":"966","DOI":"10.1128\/CDLI.9.5.966-971.2002","volume":"9","author":"O'Rourke","year":"2002","unstructured":"O'Rourke KI, Duncan JV, Logan JR, Anderson AK, Norden DK, Williams ES, Combs BA, Stobart RH, Moss GE, Sutton DL (2002) Active surveillance for scrapie by third eyelid biopsy and genetic susceptibility testing of flocks of sheep in Wyoming. Clin Diagn Lab Immunol 9:966\u2013971","journal-title":"Clin Diagn Lab Immunol"},{"key":"0524_CR33","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1111\/j.1751-0813.1992.tb07506.x","volume":"69","author":"Peet","year":"1992","unstructured":"Peet R, Curran J (1992) Spongiform encephalopathy in an imported cheetah (Acinonyx jubatus). Aust Vet J 69:171","journal-title":"Aust Vet J"},{"key":"0524_CR34","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1126\/science.6801762","volume":"216","author":"Prusiner","year":"1982","unstructured":"Prusiner SB (1982) Novel proteinaceous infectious particles cause scrapie. Science 216:136\u2013144","journal-title":"Science"},{"key":"0524_CR35","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1126\/science.278.5336.245","volume":"278","author":"Prusiner","year":"1997","unstructured":"Prusiner SB (1997a) Prion diseases and the BSE crisis. Science 278:245\u2013251","journal-title":"Science"},{"key":"0524_CR36","first-page":"S21","volume":"3","author":"Prusiner","year":"1997","unstructured":"Prusiner SB (1997b) Transmissible encephalopathies (prion diseases). Structural biology and genetics of prions. J Neurovirol 3:S21","journal-title":"J Neurovirol"},{"key":"0524_CR37","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1136\/vr.148.14.437","volume":"148","author":"Ryder","year":"2001","unstructured":"Ryder SJ, Wells GAH, Bradshaw JM, Pearson GR (2001) Inconsistent detection of PrP in extraneural tissues of cats with feline spongiform encephalopathy. Vet Rec 148:437\u2013441","journal-title":"Vet Rec"},{"key":"0524_CR38","doi-asserted-by":"crossref","first-page":"2422","DOI":"10.1210\/endo.140.5.6896","volume":"140","author":"Schelcher","year":"1999","unstructured":"Schelcher F, Picard-Hagen N, Laroute V, Gayrard V, Popot MA, Andreoletti O, Toutain PL (1999) Corticoid concentrations are increased in the plasma and urine of ewes with naturally occurring scrapie. Endocrinology 140:2422\u20132425","journal-title":"Endocrinology"},{"key":"0524_CR39","doi-asserted-by":"publisher","first-page":"31479","DOI":"10.1074\/jbc.C100278200","volume":"276","author":"Shaked","year":"2001","unstructured":"Shaked GM, Shaked Y, KarivInbal Z, Halimi M, Avraham I, Gabizon R (2001) A protease-resistant prion protein isoform is present in urine of animals and humans affected with prion diseases. J Biol Cell 276:31479\u201331482","journal-title":"J Biol Cell"},{"key":"0524_CR40","doi-asserted-by":"crossref","first-page":"2327","DOI":"10.1099\/0022-1317-82-10-2327","volume":"82","author":"Sigurdson","year":"2001","unstructured":"Sigurdson CJ, Spraker TR, Miller MW, Oesch B, Hoover EA (2001) PrPCWD in the myenteric plexus, vagosympathetic trunk and endocrine glands of deer with chronic wasting disease. J Gen Virol 82:2327\u20132334","journal-title":"J Gen Virol"},{"key":"0524_CR41","doi-asserted-by":"crossref","first-page":"2389","DOI":"10.1099\/0022-1317-78-9-2389","volume":"78","author":"Somerville","year":"1997","unstructured":"Somerville RA, Birkett CR, Farquhar CF, Hunter N, Goldmann W, Dornan J, Grover D, Hennion RM, Percy C, Foster J, Jeffrey M (1997) Immunodetection of PrPsc in spleens of some scrapie-infected sheep but not BSE-infected cows. J Gen Virol 78:2389\u20132396","journal-title":"J Gen Virol"},{"key":"0524_CR42","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1016\/S0140-6736(01)05403-4","volume":"358","author":"Wadsworth","year":"2001","unstructured":"Wadsworth JDF, Joiner S, Hill AF, Campbell TA, Desbruslais M, Luthert PJ, Collinge J (2001) Tissue distribution of protease resistant prion protein in variant Creutzfeldt-Jakob disease using a highly sensitive immunoblotting assay. Lancet 358:171\u2013180","journal-title":"Lancet"},{"key":"0524_CR43","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1136\/vr.121.18.419","volume":"121","author":"Wells","year":"1987","unstructured":"Wells GAH, Scott AC, Johnson CT, Gunning RF, Hancock RD, Jeffrey M, Dawson M, Bradley R (1987) A novel progressive spongiform encephalopathy in cattle. Vet Rec 121:419\u2013420","journal-title":"Vet Rec"},{"key":"0524_CR44","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1136\/vr.131.19.431","volume":"131","author":"Willoughby","year":"1992","unstructured":"Willoughby D, Kelly D, Lyon D, Wells G (1992) Spongiform encephalopathy in a captive puma. Vet Rec 131:431\u2013434","journal-title":"Vet Rec"},{"key":"0524_CR47","unstructured":"Wolfgang K (1995) Atlas d'histologie, 2nd edn. M\u00e9decine-Sciences Flammarion, Paris"},{"key":"0524_CR45","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1136\/vr.129.11.233","volume":"129","author":"Wyatt","year":"1991","unstructured":"Wyatt JM, Pearson GR, Smerdon TN, Gruffydd-Jones TJ, Wells GAH, Wilesmith JW (1991) Naturally occurring scrapie-like encephalopathy in five domestic cats. Vet Rec 129:233\u2013236","journal-title":"Vet Rec"}],"container-title":["Histochemistry and Cell Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00418-003-0524-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00418-003-0524-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00418-003-0524-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,2,11]],"date-time":"2021-02-11T19:29:52Z","timestamp":1613071792000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00418-003-0524-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,5]]},"references-count":47,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2003,5]]}},"alternative-id":["0524"],"URL":"https:\/\/doi.org\/10.1007\/s00418-003-0524-5","relation":{},"ISSN":["0948-6143","1432-119X"],"issn-type":[{"value":"0948-6143","type":"print"},{"value":"1432-119X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,5]]}}}