{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T20:15:14Z","timestamp":1791231314848,"version":"4.1.0"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2006,2,21]],"date-time":"2006-02-21T00:00:00Z","timestamp":1140480000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Histochem Cell Biol"],"published-print":{"date-parts":[[2006,6]]},"DOI":"10.1007\/s00418-006-0160-y","type":"journal-article","created":{"date-parts":[[2006,2,20]],"date-time":"2006-02-20T07:55:29Z","timestamp":1140422129000},"page":"615-624","source":"Crossref","is-referenced-by-count":68,"title":["Location of cell cycle regulators cyclin B1, cyclin A, PCNA, Ki67 and cell cycle inhibitors p21, p27 and p57 in human first trimester placenta and deciduas"],"prefix":"10.1007","volume":"125","author":[{"given":"Emin T\u00fcrkay","family":"Korgun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ciler","family":"Celik-Ozenci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuray","family":"Acar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sevil","family":"Cayli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gernot","family":"Desoye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramazan","family":"Demir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2006,2,21]]},"reference":[{"key":"160_CR1","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1242\/jcs.101.3.529","volume":"101","author":"E Bailly","year":"1992","unstructured":"Bailly E, Pines J, Hunter T, Bornens M (1992) Cytoplasmic accumulation of cyclin B1 in human cells: association with a detergent-resistant compartment and with the centrosome. J Cell Sci 101:529\u2013545","journal-title":"J Cell Sci"},{"key":"160_CR2","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1053\/plac.1999.0396","volume":"20","author":"A Bamberger","year":"1999","unstructured":"Bamberger A, Sudahl S, Bamberger CM, Schulte HM, Loning T (1999) Expression patterns of the cell-cycle inhibitor p27 and the cell-cycle promoter cyclin E in the human placenta throughout gestation: implications for the control of proliferation. Placenta 20:401\u2013406","journal-title":"Placenta"},{"key":"160_CR3","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1053\/plac.2000.0559","volume":"21","author":"A Blaschitz","year":"2000","unstructured":"Blaschitz A, Weiss U, Dohr G, Desoye G (2000) Antibody reaction patterns in first trimester placenta: implications for trophoblast isolation and purity screening. Placenta 21:733\u2013741","journal-title":"Placenta"},{"key":"160_CR4","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/0165-0378(88)90028-9","volume":"14","author":"JN Bulmer","year":"1988","unstructured":"Bulmer JN, Morrison L, Johnson PM (1988) Expression of the proliferation markers Ki67 and transferrin receptor by human trophoblast populations. J Reprod Immunol 14:291\u2013302","journal-title":"J Reprod Immunol"},{"key":"160_CR5","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1007\/s004410051236","volume":"295","author":"M Cervar","year":"1999","unstructured":"Cervar M, Blaschitz A, Dohr G, Desoye G (1999) Paracrine regulation of distinct trophoblast functions in vitro by placental macrophages. Cell Tissue Res 295:297\u2013305","journal-title":"Cell Tissue Res"},{"key":"160_CR6","doi-asserted-by":"crossref","first-page":"2165","DOI":"10.1038\/sj.onc.1203573","volume":"19","author":"BD Chang","year":"2000","unstructured":"Chang BD, Broude EV, Fang J, Kalinichenko TV, Abdryashitov R, Poole JC, Roninson IB (2000) p21Waf\/Cip1\/Sdi1-induced growth arrest is associated with depletion of mitosis-control proteins and leads to abnormal mitosis and endoreduplication in recovering cells. Oncogene 19:2165\u20132170","journal-title":"Oncogene"},{"key":"160_CR7","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/s00441-004-0880-z","volume":"317","author":"M Falco De","year":"2004","unstructured":"De Falco M, Fedele V, Cobellis L, Mastrogiacomo A, Giraldi D, Leone S, De Luca L, Laforgia V, De Luca A (2004) Pattern of expression of cyclin D1\/CDK4 complex in human placenta during gestation. Cell Tissue Res 317:187\u2013194","journal-title":"Cell Tissue Res"},{"key":"160_CR8","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0143-4004(97)90066-7","volume":"18","author":"JA DeLoia","year":"1997","unstructured":"DeLoia JA, Burlingame JM, Krasnow JA (1997) Differential expression of G1 cyclins during human placentogenesis. Placenta 18:9\u201316","journal-title":"Placenta"},{"key":"160_CR9","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1128\/MCB.18.1.546","volume":"18","author":"V Dulic","year":"1998","unstructured":"Dulic V, Stein GH, Far DF, Reed SI (1998) Nuclear accumulation of p21Cip1 at the onset of mitosis: a role at the G2\/M-phase transition. Mol Cell Biol 18:546\u2013557","journal-title":"Mol Cell Biol"},{"key":"160_CR10","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1006\/excr.2000.4888","volume":"257","author":"E Endl","year":"2000","unstructured":"Endl E, Gerdes J (2000) The Ki-67 protein: fascinating forms and an unknown function. Exp Cell Res 257:231\u2013237","journal-title":"Exp Cell Res"},{"key":"160_CR11","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1128\/MCB.23.2.555-565.2003","volume":"23","author":"FB Engel","year":"2003","unstructured":"Engel FB, Hauck L, Boehm M, Nabel EG, Dietz R, von Harsdorf R (2003) p21(CIP1) controls proliferating cell nuclear antigen level in adult cardiomyocytes. Mol Cell Biol 23:555\u2013565","journal-title":"Mol Cell Biol"},{"key":"160_CR12","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1016\/S0002-9440(10)64648-2","volume":"157","author":"O Genbacev","year":"2000","unstructured":"Genbacev O, McMaster MT, Fisher SJ (2000) A repertoire of cell cycle regulators whose expression is coordinated with human cytotrophoblast differentiation. Am J Pathol 157:1337\u20131351","journal-title":"Am J Pathol"},{"key":"160_CR13","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/S0959-437X(96)90011-8","volume":"6","author":"JW Harper","year":"1996","unstructured":"Harper JW, Elledge SJ (1996) Cdk inhibitors in development and cancer. Curr Opin Genet Dev 6:56\u201364","journal-title":"Curr Opin Genet Dev"},{"key":"160_CR14","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1091\/mbc.11.3.1037","volume":"11","author":"N Hattori","year":"2000","unstructured":"Hattori N, Davies TC, Anson-Cartwright L, Cross JC (2000) Periodic expression of the cyclin-dependent kinase inhibitor p57 (Kip2) in trophoblast giant cells defines a G2-like gap phase of the endocycle. Mol Biol Cell 11:1037\u20131045","journal-title":"Mol Biol Cell"},{"key":"160_CR15","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1242\/dev.122.4.1051","volume":"122","author":"S Hayashi","year":"1996","unstructured":"Hayashi S (1996) A Cdc2 dependent checkpoint maintains diploidy in Drosophila. Development 122:1051\u20131058","journal-title":"Development"},{"key":"160_CR16","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/0092-8674(94)90543-6","volume":"79","author":"T Hunter","year":"1994","unstructured":"Hunter T, Pines J (1994) Cyclins and cancer. II Cyclin D and CDK inhibitors come of age. Cell 79:573\u2013582","journal-title":"Cell"},{"key":"160_CR17","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1097\/00004347-199807000-00007","volume":"17","author":"N Ichikawa","year":"1998","unstructured":"Ichikawa N, Zhai YL, Shiozawa T, Toki T, Noguchi H, Nikaido T, Fujii S (1998) Immunohistochemical analysis of cell cycle regulatory gene products in normal trophoblast and placental site trophoblastic tumor. Int J Gynecol Pathol 17:235\u2013240","journal-title":"Int J Gynecol Pathol"},{"key":"160_CR18","first-page":"21","volume":"10","author":"P Kaufmann","year":"1997","unstructured":"Kaufmann P, Castelluci M (1997) Extravillous trophoblast in the human placenta. Trophoblast Res 10:21\u201365","journal-title":"Trophoblast Res"},{"key":"160_CR19","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1101\/gad.9.6.639","volume":"9","author":"MH Lee","year":"1995","unstructured":"Lee MH, Reynisdottir I, Massague J (1995) Cloning of p57KIP2, a cyclin-dependent kinase inhibitor with unique domain structure and tissue distribution. Genes Dev 9:639\u2013649","journal-title":"Genes Dev"},{"key":"160_CR20","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1016\/0092-8674(91)90042-W","volume":"66","author":"DJ Lew","year":"1991","unstructured":"Lew DJ, Dulic V, Reed SI (1991) Isolation of three novel human cyclins by rescue of G1 cyclin (Cln) function in yeast. Cell 66:1197\u20131206","journal-title":"Cell"},{"key":"160_CR21","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1091\/mbc.9.4.795","volume":"9","author":"A MacAuley","year":"1998","unstructured":"MacAuley A, Cross JC, Werb Z (1998) Reprogramming the cell cycle for endoreduplication in rodent trophoblast cells. Mol Biol Cell 9:795\u2013807","journal-title":"Mol Biol Cell"},{"key":"160_CR22","doi-asserted-by":"crossref","first-page":"3051","DOI":"10.1242\/jcs.00653","volume":"116","author":"G Maga","year":"2003","unstructured":"Maga G, Hubscher U (2003) Proliferating cell nuclear antigen (PCNA): a dancer with many partners. J Cell Sci 116:3051\u20133060","journal-title":"J Cell Sci"},{"key":"160_CR23","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1002\/(SICI)1521-1878(199812)20:12<1020::AID-BIES8>3.0.CO;2-D","volume":"20","author":"K Nakayama","year":"1998","unstructured":"Nakayama K, Nakayama K (1998) Cip\/Kip cyclin-dependent kinase inhibitors: brakes of the cell cycle engine during development. Bioessays 20:1020\u20131029","journal-title":"Bioessays"},{"key":"160_CR24","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1128\/MCB.18.1.629","volume":"18","author":"AB Niculescu","year":"1998","unstructured":"Niculescu AB, Chen X, Smeets M, Hengst L, Prives C, Reed SI (1998) Effects of p21(Cip1\/Waf1) at both the G1\/S and the G2\/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication. Mol Cell Biol 18:629\u2013664","journal-title":"Mol Cell Biol"},{"key":"160_CR25","doi-asserted-by":"crossref","first-page":"4877","DOI":"10.1128\/MCB.17.8.4877","volume":"17","author":"VV Ogryzko","year":"1997","unstructured":"Ogryzko VV, Wong P, Howard BH (1997) WAF1 retards S-phase progression primarily by inhibition of cyclin-dependent kinases. Mol Cell Biol 17:4877\u20134882","journal-title":"Mol Cell Biol"},{"key":"160_CR26","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1038\/modpathol.3880432","volume":"14","author":"M Olvera","year":"2001","unstructured":"Olvera M, Harris S, Amezcua CA, McCourty A, Rezk S, Koo C, Felix JC, Brynes RK (2001) Immunohistochemical expression of cell cycle proteins E2F-1, Cdk-2, cyclin E, p27 (kip1), and Ki-67 in normal placenta and gestational trophoblastic disease. Mod Pathol 14:1036\u20131042","journal-title":"Mod Pathol"},{"key":"160_CR27","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1126\/science.7863329","volume":"267","author":"SB Parker","year":"1995","unstructured":"Parker SB, Eichele G, Zhang P, Rawls A, Sands AT, Bradley A, Olson EN, Harper JW, Elledge SJ (1995) p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells. Science 267:1024\u20131027","journal-title":"Science"},{"key":"160_CR28","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1101\/gad.9.10.1149","volume":"9","author":"CJ Sherr","year":"1995","unstructured":"Sherr CJ, Roberts JM (1995) Inhibitors of mammalian G1 cyclin-dependent kinases. Genes Dev 9:1149\u20131163","journal-title":"Genes Dev"},{"key":"160_CR29","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1101\/gad.13.12.1501","volume":"13","author":"CJ Sherr","year":"1999","unstructured":"Sherr CJ, Roberts JM (1999) CDK inhibitors: positive and negative regulators of G1 phase progression. Genes Dev 13:1501\u20131512","journal-title":"Genes Dev"},{"key":"160_CR30","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1007\/BF01235751","volume":"22","author":"T Takahashi","year":"1993","unstructured":"Takahashi T, Caviness VS (1993) PCNA-binding to DNA at the G1\/S transition in proliferating cells of the developing cerebral wall. J Neurocytol 22:1096\u20131102","journal-title":"J Neurocytol"},{"key":"160_CR31","first-page":"1","volume":"1288","author":"Y Xiong","year":"1996","unstructured":"Xiong Y (1996) Why are there so many CDK inhibitors? Biochim Biophys Acta 1288:1\u20135","journal-title":"Biochim Biophys Acta"},{"key":"160_CR32","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1101\/gad.11.8.973","volume":"11","author":"Y Yan","year":"1997","unstructured":"Yan Y, Frise\u00b4n J, Lee MH, Massague\u00b4 J, Barbacid M (1997) Ablation of the CDK inhibitor p57Kip2 results in increased apoptosis and delayed differentiation during mouse development. Genes Dev 11:973\u2013983","journal-title":"Genes Dev"},{"key":"160_CR33","first-page":"1058","volume":"44","author":"TG Zybina","year":"2002","unstructured":"Zybina TG, Kaufmann P, Frank HG, Freed J, Kadyrov M, Biesterfeld S (2002) Genome multiplication of extravillous trophoblast cells in human placenta in the course of differentiation and invasion into endometrium and myometrium. I. Dynamics of polyplodization. Tsitologia 44:1058\u20131067","journal-title":"Tsitologia"},{"key":"160_CR34","first-page":"640","volume":"46","author":"TG Zybina","year":"2004","unstructured":"Zybina TG, Frank HG, Biesterfeld S, Kaufmann P (2004) Genome multiplication of extravillous trophoblast cells in human placenta in the course of differentiation and invasion into endometrium and myometrium. II. Mechanisms of polyplodization. Tsitologia 46:640\u2013648","journal-title":"Tsitologia"}],"container-title":["Histochemistry and Cell Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00418-006-0160-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00418-006-0160-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00418-006-0160-y","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,24]],"date-time":"2021-07-24T03:48:39Z","timestamp":1627098519000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00418-006-0160-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,2,21]]},"references-count":34,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2006,6]]}},"alternative-id":["160"],"URL":"https:\/\/doi.org\/10.1007\/s00418-006-0160-y","relation":{},"ISSN":["0948-6143","1432-119X"],"issn-type":[{"value":"0948-6143","type":"print"},{"value":"1432-119X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,2,21]]}}}