{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T14:00:27Z","timestamp":1761919227484},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2009,6,5]],"date-time":"2009-06-05T00:00:00Z","timestamp":1244160000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Histochem Cell Biol"],"published-print":{"date-parts":[[2009,9]]},"DOI":"10.1007\/s00418-009-0610-4","type":"journal-article","created":{"date-parts":[[2009,6,6]],"date-time":"2009-06-06T00:19:04Z","timestamp":1244247544000},"page":"339-349","source":"Crossref","is-referenced-by-count":30,"title":["Characterisation and expression of SPLUNC2, the human orthologue of rodent parotid secretory protein"],"prefix":"10.1007","volume":"132","author":[{"given":"Lynne","family":"Bingle","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frances A.","family":"Barnes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hayley","family":"Lunn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maslinda","family":"Musa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steve","family":"Webster","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. W. Ian","family":"Douglas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon S.","family":"Cross","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alec S.","family":"High","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colin D.","family":"Bingle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2009,6,5]]},"reference":[{"key":"610_CR1","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1042\/bst0310777","volume":"31","author":"WD Ball","year":"2003","unstructured":"Ball WD, Mirels L, Hand AR (2003) Psp and Smgb: a model for developmental and functional regulation in the rat major salivary glands. Biochem Soc Trans 31:777\u2013780","journal-title":"Biochem Soc Trans"},{"key":"610_CR2","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1093\/hmg\/11.8.937","volume":"11","author":"CD Bingle","year":"2002","unstructured":"Bingle CD, Craven CJ (2002) PLUNC: a novel family of candidate host defence proteins expressed in the upper airways and nasopharynx. Hum Mol Genet 11:937\u2013943","journal-title":"Hum Mol Genet"},{"key":"610_CR3","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.it.2003.11.007","volume":"25","author":"CD Bingle","year":"2004","unstructured":"Bingle CD, Craven CJ (2004) Meet the relatives: a family of BPI and LBP-related proteins. Trends Immunol 25:53\u201355","journal-title":"Trends Immunol"},{"key":"610_CR4","doi-asserted-by":"crossref","first-page":"2144","DOI":"10.1016\/j.biocel.2004.05.002","volume":"36","author":"CD Bingle","year":"2004","unstructured":"Bingle CD, Gorr SU (2004) Host defence in oral and airway epithelia: chromosome 20 contributes a new protein family. Int J Biochem Cell Biol 36:2144\u20132152","journal-title":"Int J Biochem Cell Biol"},{"key":"610_CR5","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/j.it.2008.07.001","volume":"29","author":"CD Bingle","year":"2008","unstructured":"Bingle CD, Vayarkarnam A (2008) Novel innate immune functions of the whey acidic protein family. Trends Immunol 29:444\u2013453","journal-title":"Trends Immunol"},{"key":"610_CR6","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1110\/ps.03332704","volume":"13","author":"CD Bingle","year":"2004","unstructured":"Bingle CD, LeClair EE, Havard S, Bingle L, Gillingham P, Craven CJ (2004) Phylogenetic and evolutionary analysis of the PLUNC gene family. Protein Sci 13:422\u2013430","journal-title":"Protein Sci"},{"key":"610_CR7","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1002\/path.1726","volume":"205","author":"L Bingle","year":"2005","unstructured":"Bingle L, Cross SS, High AS, Wallace WA, Devine DA, Havard S, Campos MA, Bingle CD (2005) SPLUNC1 (PLUNC) is expressed in glandular tissues of the respiratory tract and in cancers with a glandular phenotype. J Path 205:491\u2013497","journal-title":"J Path"},{"key":"610_CR8","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1186\/1465-9921-7-61","volume":"7","author":"L Bingle","year":"2006","unstructured":"Bingle L, Cross SS, High AS, Wallace WA, Rassl D, Yuan G, Hellstrom I, Campos MA, Bingle CD (2006) WFDC2 (HE4): a potential role in the innate immunity of the oral cavity and respiratory tract and the development of adenocarcinomas of the lung. Respir Res 7:61","journal-title":"Respir Res"},{"key":"610_CR9","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1165\/rcmb.2003-0142OC","volume":"30","author":"MA Campos","year":"2004","unstructured":"Campos MA, Abreu AR, Nlend MC, Cobas MA, Conner GE, Whitney PL (2004) Purification and characterization of PLUNC from human tracheobronchial secretions. Am J Respir Cell Mol Biol 30:184\u2013192","journal-title":"Am J Respir Cell Mol Biol"},{"key":"610_CR10","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1093\/hmg\/ddg078","volume":"12","author":"RD Emes","year":"2003","unstructured":"Emes RD, Goodstadt L, Winter EE, Ponting CP (2003) Comparison of the genomes of human and mouse lays the foundation of genome zoology. Hum Mol Genet 12:701\u2013709","journal-title":"Hum Mol Genet"},{"key":"610_CR11","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1042\/bst0310815","volume":"31","author":"C Geetha","year":"2003","unstructured":"Geetha C, Venkatesh SG, Dunn BH, Gorr SU (2003) Expression and anti-bacterial activity of human parotid secretory protein (PSP). Biochem Soc Trans 31:815\u2013818","journal-title":"Biochem Soc Trans"},{"key":"610_CR12","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1177\/154405910508400208","volume":"84","author":"C Geetha","year":"2005","unstructured":"Geetha C, Venkatesh SG, Bingle L, Bingle CD, Gorr SU (2005) Design and validation of anti-inflammatory peptides from human parotid secretory protein. J Dent Res 84:149\u2013153","journal-title":"J Dent Res"},{"key":"610_CR13","doi-asserted-by":"crossref","first-page":"2118","DOI":"10.1016\/j.peptides.2008.09.019","volume":"29","author":"SU Gorr","year":"2008","unstructured":"Gorr SU, Sotsky JB, Shelar AP, Demuth DR (2008) Design of bacteria-agglutinating peptides derived from parotid secretory protein, a member of the bactericidal\/permeability increasing-like protein family. Peptides 29:2118\u20132127","journal-title":"Peptides"},{"key":"610_CR14","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1021\/pr060065m","volume":"5","author":"T Guo","year":"2006","unstructured":"Guo T, Rudnick PA, Wang W, Lee CS, Devoe DL, Balgley BM (2006) Characterization of the human salivary proteome by capillary isoelectric focusing\/nanoreversed-phase liquid chromatography coupled with ESI-tandem MS. J Proteome Res 5:1469\u20131478","journal-title":"J Proteome Res"},{"key":"610_CR15","doi-asserted-by":"crossref","first-page":"1944","DOI":"10.1016\/j.molimm.2007.10.032","volume":"45","author":"B Haigh","year":"2008","unstructured":"Haigh B, Hood K, Broadhurst M, Medele S, Callaghan M, Smolenski G, Dines M, Wheeler T (2008) The bovine salivary proteins BSP30a and BSP30b are independently expressed BPI-like proteins with anti-Pseudomonas activity. Mol Immunol 45:1944\u20131951","journal-title":"Mol Immunol"},{"key":"610_CR16","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1177\/154405910708600802","volume":"86","author":"EJ Helmerhorst","year":"2007","unstructured":"Helmerhorst EJ, Oppenheim FG (2007) Saliva: a dynamic proteome. J Dent Res 86:680\u2013693","journal-title":"J Dent Res"},{"key":"610_CR17","doi-asserted-by":"crossref","first-page":"R1306","DOI":"10.1152\/ajpregu.00007.2004","volume":"288","author":"W Khovidhunkit","year":"2005","unstructured":"Khovidhunkit W, Hachem JP, Medzihradszky KF, Duchateau PN, Shigenaga JK, Moser AH, Movsesyan I, Naya-Vigne J, Kane JP, Feingold KR, Grunfeld C (2005) Parotid secretory protein is an HDL-associated protein with anticandidal activity. Am J Physiol Regul Integr Comp Physiol 288:R1306\u2013R1315","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"610_CR18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1093\/nar\/13.1.1","volume":"13","author":"HO Madsen","year":"1985","unstructured":"Madsen HO, Hjorth JP (1985) Molecular cloning of mouse PSP mRNA. Nucleic Acids Res 13:1\u201313","journal-title":"Nucleic Acids Res"},{"key":"610_CR19","doi-asserted-by":"crossref","first-page":"2679","DOI":"10.1016\/S0021-9258(18)45934-0","volume":"267","author":"L Mirels","year":"1992","unstructured":"Mirels L, Ball WD (1992) Neonatal rat submandibular gland protein SMG-A and parotid secretory protein are alternatively regulated members of a salivary protein multigene family. J Biol Chem 267:2679\u20132687","journal-title":"J Biol Chem"},{"key":"610_CR20","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1042\/bj3300437","volume":"330","author":"L Mirels","year":"1998","unstructured":"Mirels L, Miranda AJ, Ball WD (1998) Characterization of the rat salivary-gland B1-immunoreactive proteins. Biochem J 330:437\u2013444","journal-title":"Biochem J"},{"key":"610_CR21","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1111\/j.1574-695X.2006.00161.x","volume":"48","author":"C Plummer","year":"2006","unstructured":"Plummer C, Douglas CWI (2006) Relationship between the ability of oral streptococci to interact with platelet glycoprotein Ib\u03b1 and with the salivary low-molecular weight mucin, MG2. FEMS Immunol Med Microbiol 48:390\u2013399","journal-title":"FEMS Immunol Med Microbiol"},{"key":"610_CR22","doi-asserted-by":"crossref","first-page":"1493","DOI":"10.1021\/pr050492k","volume":"5","author":"P Ramachandran","year":"2006","unstructured":"Ramachandran P, Boontheung P, Xie Y, Sondej M, Wong DT, Loo JA (2006) Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry. J Proteome Res 5:1493\u20131503","journal-title":"J Proteome Res"},{"key":"610_CR23","first-page":"G863","volume":"272","author":"CP Robinson","year":"1997","unstructured":"Robinson CP, Bounous DI, Alford CE, Nguyen KT, Nanni JM, Peck AB, Ammon B, Humphreys-Beher MG (1997) PSP expression in murine lacrimal glands and function as a bacteria-binding protein in exocrine secretions. Am J Physiol 272:G863\u2013G871","journal-title":"Am J Physiol"},{"key":"610_CR24","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/0022-2836(86)90277-9","volume":"192","author":"P Shaw","year":"1986","unstructured":"Shaw P, Schibler U (1986) Structure and expression of the parotid secretory protein gene of mouse. J Mol Biol 192:567\u2013576","journal-title":"J Mol Biol"},{"key":"610_CR25","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1111\/j.1600-0765.2005.00781.x","volume":"40","author":"H Shiba","year":"2005","unstructured":"Shiba H, Venkatesh SG, Gorr SU, Barbieri G, Kurihara H, Kinane DF (2005) Parotid secretory protein is expressed and inducible in human gingival keratinocytes. J Periodontal Res 40:153\u2013157","journal-title":"J Periodontal Res"},{"key":"610_CR26","doi-asserted-by":"crossref","first-page":"2152","DOI":"10.1021\/pr060580k","volume":"6","author":"WL Siqueira","year":"2007","unstructured":"Siqueira WL, Zhang W, Helmerhorst EJ, Gygi SP, Oppenheim FG (2007) Identification of protein components in vivo human acquired enamel pellicle using LC-ESI-MS\/MS. J Proteome Res 6:2152\u20132160","journal-title":"J Proteome Res"},{"key":"610_CR27","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1177\/154405910808700508","volume":"87","author":"WL Siqueira","year":"2008","unstructured":"Siqueira WL, Salih E, Wan DL, Helmerhorst EJ, Oppenheim FG (2008) Proteome of human minor salivary gland secretion. J Dent Res 87:445\u2013450","journal-title":"J Dent Res"},{"key":"610_CR28","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1111\/j.1601-0825.2007.01429.x","volume":"14","author":"PA Vargas","year":"2008","unstructured":"Vargas PA, Speight PM, Bingle CD, Barrett AW, Bingle L (2008) Expression of PLUNC family members in benign and malignant salivary gland tumours. Oral Dis 14:613\u2013619","journal-title":"Oral Dis"},{"key":"610_CR29","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1002\/pmic.200300638","volume":"4","author":"R Vitorino","year":"2004","unstructured":"Vitorino R, Lobo MJ, Ferrer-Correira AJ, Dubin JR, Tomer KB, Domingues PM, Amado FM (2004) Identification of human whole saliva protein components using proteomics. Proteomics 4:1109\u20131115","journal-title":"Proteomics"},{"key":"610_CR30","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1002\/pmic.200500125","volume":"6","author":"A Walz","year":"2006","unstructured":"Walz A, Stuhler K, Wattenberg A, Hawranke E, Meyer HE, Schmalz G, Bluggel M, Ruhl S (2006) Proteome analysis of glandular parotid and submandibular\u2013sublingual saliva in comparison to whole human saliva by two-dimensional gel electrophoresis. Proteomics 6:1631\u20131639","journal-title":"Proteomics"},{"key":"610_CR31","doi-asserted-by":"crossref","first-page":"13698","DOI":"10.1074\/jbc.274.19.13698","volume":"274","author":"WM Weston","year":"1999","unstructured":"Weston WM, LeClair EE, Trzyna W, McHugh KM, Nugent P, Lafferty CM, Ma L, Tuan RS, Greene RM (1999) Differential display identification of plunc, a novel gene expressed in embryonic palate, nasal epithelium, and adult lung. J Biol Chem 274:13698\u201313703","journal-title":"J Biol Chem"},{"key":"610_CR32","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/S0167-4781(02)00508-0","volume":"1579","author":"TT Wheeler","year":"2002","unstructured":"Wheeler TT, Haigh BJ, McCracken JY, Wilkins RJ, Morris CA, Grigor MR (2002) The BSP30 salivary proteins from cattle, LUNX\/PLUNC and von Ebner\u2019s minor salivary gland protein are members of the PSP\/LBP superfamily of proteins. Biochim Biophys Acta 1579:92\u2013100","journal-title":"Biochim Biophys Acta"},{"key":"610_CR33","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1186\/1471-2164-8-75","volume":"8","author":"TT Wheeler","year":"2007","unstructured":"Wheeler TT, Hood KA, Maqbool N, McEwan JC, Bingle CD, Zhao S (2007) Expansion of the bactericidal\/permeability increasing-like (BPI-like) protein locus in cattle. BMC Genomics 8:75","journal-title":"BMC Genomics"}],"container-title":["Histochemistry and Cell Biology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00418-009-0610-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s00418-009-0610-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s00418-009-0610-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,7]],"date-time":"2021-10-07T01:16:38Z","timestamp":1633569398000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s00418-009-0610-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,6,5]]},"references-count":33,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2009,9]]}},"alternative-id":["610"],"URL":"https:\/\/doi.org\/10.1007\/s00418-009-0610-4","relation":{},"ISSN":["0948-6143","1432-119X"],"issn-type":[{"value":"0948-6143","type":"print"},{"value":"1432-119X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,6,5]]}}}